抗癌天然产物库

Anti-Tumor Natural Product Library

产品编号： L6700

癌症是严重危害人类健康的疾病, 从天然产物中寻找预防和治疗恶性肿瘤的活性成分始终是国内外肿瘤药物开发的热门领域，众多药物化学家们一直在致力于天然抗瘤药物的开发。随着对肿瘤发生、恶变的分子机制研究不断深入，人们以肿瘤发生发展过程中相关酶、受体为作用靶点, 筛选出一系列新的有潜在抗癌活性的天然先导化合物。据权威机构统计，从1981年至今，99种小分子抗癌药物中的79种是以天然产物为基础研制成功的，例如紫杉烷类、喜树碱类和长春碱类等热门抗肿瘤药物。天然产物是一个巨大的药物开发宝库，天然产物的研究与开发历来是人类寻找新药以及向疾病作斗争的重要手段。借助天然产物的结构先导、修饰和改造也促进了合成药物的迅速发展。

TargetMol 精心筛选1812 种来源于植物、动物或微生物的具有已知或潜在抗肿瘤活性天然产物，性价比高，能够为您提供肿瘤药物开发、天然先导化合物筛选等研究的有力工具。

陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。

产品规格

技术资料

陶术生物化合物库目录(2.8MB)

库化合物信息

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产品描述

1812种已知活性天然产物的独特集合，是肿瘤药物开发、抗癌先导化合物筛选等领域的有力工具，可用于HTS和HCS。
全部产品活性已知：提供产品的生物学信息和药物学信息，为筛选提供理论方向和研究基础；
来源清晰：精选来自动物、植物、微生物的已知活性天然产物；更具体到植物种属，并标注准确英文名与拉丁名，方便您的后期研究确证。
信息全面：从化合物结构到溶解度，从信号通路、作用靶点到生物活性信息均有详细描述。
性价比高：剔除了价格昂贵但成药性差的天然产物，让您用更少的成本得到更多高品质的天然产物。

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化合物库组成

Apoptosis (374)

Endogenous Metabolite (290)

Autophagy (209)

NF-κB (172)

Antibacterial (168)

COX (96)

Reactive Oxygen Species (93)

Antioxidant (70)

Antibiotic (68)

P450 (63)

TNF (63)

Parasite (59)

Antifungal (54)

DNA/RNA Synthesis (52)

Influenza Virus (51)

ERK (44)

Akt (43)

HIV Protease (41)

p38 MAPK (41)

PPAR (41)

Caspase (40)

IL Receptor (40)

STAT (40)

GABA Receptor (36)

AMPK (35)

AChR (33)

Calcium Channel (32)

NO Synthase (32)

PI3K (28)

MMP (28)

BCL (27)

Ferroptosis (26)

JNK (26)

Estrogen Receptor/ERR (25)

Estrogen/progestogen Receptor (24)

Dehydrogenase (24)

Topoisomerase (24)

AChE (24)

Nrf2 (24)

TRP/TRPV Channel (23)

PKC (23)

Lipoxygenase (23)

5-HT Receptor (23)

Microtubule Associated (23)

Mitophagy (22)

ROS (22)

NOS (21)

Virus Protease (21)

P-gp (21)

ATPase (19)

Adrenergic Receptor (19)

Potassium Channel (19)

Anti-infection (19)

Tyrosinase (19)

ADC Cytotoxin (18)

HSV (18)

Wnt/beta-catenin (16)

PARP (16)

HDAC (16)

Antifection (15)

EGFR (15)

Antiviral (15)

Prostaglandin Receptor (15)

Sodium Channel (15)

HBV (14)

PDE (14)

JAK (14)

Interleukin (13)

TLR (13)

Beta Amyloid (13)

Immunology/Inflammation related (12)

Dopamine Receptor (11)

Nucleoside Antimetabolite/Analog (11)

mTOR (11)

TGF-beta/Smad (11)

SARS-CoV (11)

HIF/HIF Prolyl-Hydroxylase (11)

CDK (10)

Glucosidase (10)

Sirtuin (10)

Adenosine Receptor (9)

PKA (9)

VEGFR (9)

MAO (9)

Mitochondrial Metabolism (9)

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transporter (9)

HCV Protease (8)

NMDAR (8)

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MEK (8)

Cannabinoid Receptor (8)

NOD (8)

Reductase (7)

iGluR (7)

LDL (7)

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p53 (7)

BACE (6)

Histamine Receptor (6)

Phosphatase (6)

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FAK (5)

Proteasome (4)

Transferase (4)

Src (4)

Integrin (4)

Amino Acids and Derivatives (4)

NADPH (4)

GSK-3 (4)

MRP (4)

Serine/threonin kinase (4)

cell cycle arrest (4)

IAP (4)

Fatty Acid Synthase (4)

CCR (4)

Xanthine Oxidase (4)

GluR (4)

CaMK (4)

PGE Synthase (4)

Free radical scavengers (4)

Histone Acetyltransferase (4)

PDK (4)

FGFR (4)

Platelet aggregation (4)

HMG-CoA Reductase (4)

NOD-like Receptor (NLR) (4)

HER (4)

Chloride channel (3)

Proton pump (3)

c-Met/HGFR (3)

DNA Alkylator/Crosslinker (3)

RAAS (3)

Glutathione Peroxidase (3)

ABC (3)

Serine Protease (3)

Cysteine Protease (3)

Liver X Receptor (3)

Aryl Hydrocarbon Receptor (3)

P2X Receptor (3)

Hedgehog/Smoothened (3)

CXCR (3)

cAMP (3)

Indoleamine 2,3-Dioxygenase (IDO) (3)

Telomerase (3)

Lipid (3)

Trk receptor (3)

GST (3)

Retinoid Receptor (3)

ribosome (3)

Syk (3)

DNA Methyltransferase (3)

Ras (3)

S6 Kinase (3)

Imidazoline Receptor (3)

DHFR (2)

ROR (2)

Arginase (2)

Progesterone Receptor (2)

Pim (2)

Leukotriene Receptor (2)

Glucokinase (2)

Vitamin (2)

RANKL/RANK (2)

Amylase (2)

E1/E2/E3 Enzyme (2)

Adiponectin receptor (2)

Bcr-Abl (2)

PAFR (2)

Monoamine Transporter (2)

Smo (2)

PDGFR (2)

PAK (2)

DNA (2)

SGLT (2)

Beta-Secretase (2)

Acyltransferase (2)

OAT (2)

Aminopeptidase (2)

GPCR19 (2)

Pyroptosis (2)

Casein Kinase (2)

RSV (2)

ATM/ATR (2)

IRAK (2)

S1P Receptor (2)

Thyroid hormone receptor(THR) (1)

Mdm2 (1)

Adenylyl cyclase (1)

CAT (1)

Transaminase (1)

stilbene oxidase (1)

Hydrogenase (1)

Histone Methyltransferase (1)

Dynamin (1)

MyD88 (1)

LPL Receptor (1)

P2Y Receptor (1)

LTR (1)

DYRK (1)

RAR/RXR (1)

Lipase (1)

PERK (1)

gp120/CD4 (1)

Factor Xa (1)

Melatonin Receptor (1)

OCT (1)

c-Myc (1)

Serotonin Transporter (1)

Glutaminase (1)

IDO (1)

IRE1 (1)

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Fas/FasL (1)

Raf (1)

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Phosphorylase (1)

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Bombesin Receptor (1)

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Bradykinin Receptor (1)

Somatostatin (1)

Chk (1)

PAD (1)

Aurora Kinase (1)

Norepinephrine (1)

ATP Citrate Lyase (1)

BCRP (1)

Glutathione reductase (1)

Survivin (1)

Decarboxylase (1)

hCE (1)

PAI-1 (1)

ALK (1)

CRISPR/Cas9 (1)

PLK (1)

FLT (1)

NADPH-oxidase (1)

cholecystokinin (1)

Thrombin (1)

ROS Kinase (1)

CFTR (1)

PD-1/PD-L1 (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

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