抗肥胖化合物库

Anti-Obesity Compound Library

产品编号： L7100

近年来肥胖已成为全球普遍的公共健康问题，肥胖是一种由多种因素（遗传、饮食习惯、生活方式和环境）相互作用引起的复杂的疾病，通常伴随着胰岛素抵抗、氧化应激和炎症标志物表达增加，导致体内脂肪含量增加。肥胖容易引起糖尿病，高血压，动脉硬化等多种代谢紊乱性疾病。肥胖管理的基本策略（如饮食控制、体育运动、手术治疗）分别具有不同程度的局限性和副作用。因此，许多研究人员试图从食物或药物中寻找出抗肥胖的生物活性成分，特别是抑制脂肪等高能量物质吸收过程的化合物、促进脂肪分解的化合物、增加机体代谢能量消耗的化合物，这些化合物包括：脂肪酶抑制剂、a-葡萄糖苷酶抑制剂、麦芽糖酶抑制剂等。

随着经济发展，肥胖问题已成为全球面临的严峻问题，所以科学家对肥胖的关注和研究更是有增无减。通过对文献和公开资料的整理，我们精心筛选了2450 个抗肥胖化合物组成抗肥胖化合物库，适合于抗肥胖的相关研究。

陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。

产品规格

技术资料

陶术生物化合物库目录(2.8MB)

库化合物信息

Excel

SDF

产品描述

2450个抗肥胖化合物的独特集合，可用于高通量筛选和高内涵筛选；
提供产品的来源、化学信息和生物学信息，为筛选提供理论方向和研究基础；
结构多样，药效显著，可渗透细胞；
NMR和HPLC技术保证产品高纯度。

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化合物库组成

Autophagy (197)

Apoptosis (191)

PI3K (180)

5-HT Receptor (113)

mTOR (104)

Adrenergic Receptor (103)

PPAR (100)

GSK-3 (81)

Histamine Receptor (80)

Dopamine Receptor (75)

Reactive Oxygen Species (73)

Raf (71)

Akt (69)

ERK (55)

p38 MAPK (52)

CDK (52)

AMPK (51)

Lipoxygenase (50)

Ras (45)

Wnt/beta-catenin (44)

VEGFR (44)

MAPK (41)

MEK (41)

DNA-PK (38)

JAK (35)

Phospholipase (35)

PKA (32)

COX (32)

TGF-beta/Smad (32)

AChR (32)

Antibacterial (29)

S6 Kinase (29)

Src (28)

FAAH (28)

ATM/ATR (28)

Kras (28)

PDGFR (27)

JNK (24)

ALK (24)

GPR (23)

Ferroptosis (22)

ROS (22)

Fatty Acid Synthase (22)

FLT (22)

Lipase (21)

Potassium Channel (21)

Prostaglandin Receptor (20)

c-Kit (20)

PDK (19)

PKC (18)

NF-κB (18)

Serotonin Transporter (17)

Norepinephrine (17)

Dehydrogenase (16)

Parasite (16)

Calcium Channel (16)

Aurora Kinase (16)

Casein Kinase (16)

Endogenous Metabolite (16)

PI4K (16)

FGFR (16)

Cannabinoid Receptor (16)

P450 (15)

Antibiotic (15)

Tyrosine Kinases (14)

Rho (14)

Hedgehog/Smoothened (14)

Mitophagy (13)

Nrf2 (13)

ROCK (12)

PDE (12)

SGLT (12)

c-RET (12)

Antifungal (11)

CETP (11)

Glucagon Receptor (11)

Opioid Receptor (11)

transporter (11)

Acetyl-CoA Carboxylase (11)

TNF (11)

Transferase (10)

Antioxidant (10)

TRP/TRPV Channel (10)

Bcr-Abl (10)

Stearoyl-CoA Desaturase (SCD) (10)

Adenosine Receptor (9)

Chk (9)

MLK (9)

HIV Protease (8)

c-Met/HGFR (8)

PARP (8)

SIK (8)

IGF-1R (8)

EGFR (8)

Trk receptor (8)

Influenza Virus (8)

Melanocortin Receptor (8)

Sodium Channel (8)

ROS Kinase (8)

Virus Protease (7)

Smo (7)

IL Receptor (7)

OX Receptor (7)

CaMK (7)

DNA/RNA Synthesis (7)

MNK (7)

STAT (7)

S1P Receptor (7)

LPL Receptor (6)

P2Y Receptor (6)

Glucocorticoid Receptor (6)

Mitochondrial Metabolism (6)

Acyltransferase (6)

MELK (6)

c-Fms (6)

FAK (6)

Histone Methyltransferase (5)

LTR (5)

DYRK (5)

Serine Protease (5)

Serine/threonin kinase (5)

Leukotriene Receptor (5)

Caspase (5)

Annexin A (5)

CXCR (5)

Endothelin Receptor (5)

Epigenetic Reader Domain (5)

Interleukin (5)

ASK (5)

SGK (5)

Sigma receptor (5)

Microtubule Associated (5)

Protease-activated Receptor (5)

Proton pump (4)

Estrogen/progestogen Receptor (4)

TOPK (4)

Phosphatase (4)

iGluR (4)

Drug Metabolite (4)

cAMP (4)

AChE (4)

Porcupine (4)

IκB/IKK (4)

HDAC (4)

Neurokinin receptor (4)

Syk (4)

NPC1L1 (3)

HCV Protease (3)

NADPH (3)

RAAS (3)

PERK (3)

GTPase (3)

Melatonin Receptor (3)

ABC (3)

Pim (3)

Myosin (3)

GRK (3)

MAGL (3)

Neuropeptide Y Receptor (3)

HSV (3)

PTEN (3)

MMP (3)

Xanthine Oxidase (3)

Epoxide Hydrolase (3)

P-gp (3)

SARS-CoV (3)

KLF (3)

cholecystokinin (3)

Tyrosinase (3)

HER (3)

Monoamine Oxidase (3)

NO Synthase (3)

Thyroid hormone receptor(THR) (2)

Melanin-concentrating Hormone Receptor (MCHR) (2)

Proteasome (2)

Chloride channel (2)

NOS (2)

Carbonic Anhydrase (2)

ADC Cytotoxin (2)

YAP (2)

BACE (2)

RAR/RXR (2)

Tie-2 (2)

Glutathione Peroxidase (2)

GNRH Receptor (2)

MRP (2)

Cysteine Protease (2)

PYK2 (2)

Aryl Hydrocarbon Receptor (2)

CSF-1R (2)

RIP kinase (2)

MT Receptor (2)

Guanylate cyclase (2)

DNA Alkylation (2)

ACK (2)

GluR (2)

DNA (2)

Lipid (2)

Antiviral (2)

HSP (2)

TLR (2)

LRRK2 (2)

Free radical scavengers (2)

Ephrin Receptor (2)

CRISPR/Cas9 (2)

PLK (2)

Apelin receptor (1)

Mdm2 (1)

ATPase (1)

PROTACs (1)

Monocarboxylate transporter (1)

Integrin (1)

MyD88 (1)

Na+/Ca2+ Exchanger (1)

c-Myc (1)

CaSR (1)

Estrogen Receptor/ERR (1)

Glucokinase (1)

Glutaminase (1)

MAO (1)

FLAP (1)

E1/E2/E3 Enzyme (1)

Adiponectin receptor (1)

UGT (1)

PAFR (1)

LDL (1)

Gamma-secretase (1)

NMDAR (1)

BTK (1)

Monoamine Transporter (1)

BCL (1)

HCN Channel (1)

PAK (1)

PGC-1α (1)

Bradykinin Receptor (1)

Somatostatin (1)

Androgen Receptor (1)

ATP Citrate Lyase (1)

OXPHOS (1)

PGE Synthase (1)

Beta-Secretase (1)

STING (1)

GPCR19 (1)

Sirtuin (1)

Decarboxylase (1)

Pyroptosis (1)

RSV (1)

Hippo pathway (1)

GST (1)

Beta Amyloid (1)

GPX (1)

LPA Receptor (1)

Hydroxylase (1)

RXFP receptor (1)

HIF (1)

Discoidin Domain Receptor (DDR) (1)

DAPK (1)

Gap Junction Protein (1)

NADPH-oxidase (1)

BMI-1 (1)

IRAK (1)

Thrombin (1)

lysosomal autophagy (1)

HIF/HIF Prolyl-Hydroxylase (1)

p53 (1)

Imidazoline Receptor (1)

PD-1/PD-L1 (1)

Kinesin (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

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