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肿瘤坏死因子家族

肿瘤坏死因子 (Tumor Necrosis Factor family, TNFs) 超家族是 II 型跨膜蛋白的蛋白质超家族,含有 TNF 同源结构域并形成三聚体。TNFs的成员可以通过细胞外蛋白水解裂解从细胞膜中释放出来,并作为细胞因子发挥作用。这些蛋白质主要由免疫细胞表达,它们调节多种细胞功能,包括免疫反应和炎症,以及增殖、分化、凋亡和胚胎发生。TNFs包含 19 个成员,与 TNF 受体超家族的 29 个成员结合。肿瘤坏死因子受体超家族(Tumor necrosis factor receptor superfamily, TNFRSF)是细胞因子受体的蛋白质超家族,其特征在于能够通过富含细胞外半胱氨酸的结构域结合TNF。TNFs的 PROSITE 模式位于蛋白质中央部分的 β 折叠中,该折叠在所有成员中都是保守的。

目录号 产品名/同用名 种属 表达系统
TMPY-02233 TRAIL/TNFSF10 Protein, Human, Recombinant Human E. coli
TMPJ-00064 OX40L/TNFSF4 Protein, Human, Recombinant (His) Human HEK293 Cells
TMPJ-00075 CD27 Ligand/CD70 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
TMPJ-00124 TNF alpha Protein, Human, Recombinant (aa 77-233, His) Human E. coli
TMPJ-00125 TNF alpha Protein, Human, Recombinant (aa 57-233, His) Human E. coli
TMPJ-00138 4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His & Flag) Human HEK293 Cells
TMPJ-00150 CD40 Ligand Protein, Human, Recombinant (Mammalian) Human HEK293 Cells
TMPJ-00151 CD40 Ligand Protein, Human, Recombinant Human E. coli
TMPJ-00152 CD40 Ligand Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
TMPJ-00153 CD40 Ligand Protein, Human, Recombinant (His & Flag) Human HEK293 Cells
TMPJ-00177 BAFF/TNFSF13B Protein, Human, Recombinant (Avi & hFc), Biotinylated Human HEK293 Cells
TMPJ-00178 BAFF/TNFSF13B Protein, Human, Recombinant (His) Human HEK293 Cells
TMPJ-00432 GITR Ligand/TNFSF18 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
TMPJ-00456 APRIL/TNFSF13 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
TMPJ-00623 BAFF/TNFSF13B Protein, Rhesus macaque, Recombinant (hFc) Rhesus HEK293 Cells
TMPJ-00920 CD40 Ligand Protein, Mouse, Recombinant (aa 112-260, His) Mouse HEK293 Cells
TMPJ-01441 OX40L/TNFSF4 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
TMPK-00053 GITR Ligand/TNFSF18 Protein, Human, Recombinant (His & Flag) Human HEK293 Cells
TMPK-00054 GITR Ligand/TNFSF18 Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated Human HEK293 Cells
TMPK-00078 CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His), FITC-Labeled Human HEK293 Cells
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