毒性化合物库

Toxic Compound Library

产品编号： L5500

Targetmol 毒性化合物库包含 262 个人工合成或天然存在的有机小分子，这些物质是能够改变细胞、代谢和膜功能的化合物，例如：DNA 合成干扰剂、酶抑制剂、受体阻断剂、膜活性化合物等细胞毒性化合物。这些化合物有些是没有继续研发的，有些是由于毒性或者其他原因停止了研究。也有些作为杀虫剂和除草剂使用。从 DNA 合成损害到细胞增殖毒性，从免疫抑制到内分泌干扰，Targetmol 毒性化合物库为您提供来源广泛、针对性强、研究明确的毒物小分子化合物，这些化合物的多样性可以增加科学家实验的视野，同时也可能揭示新的未知活性，是综合化筛选、针对性研究的有力工具。

陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。

产品规格

技术资料

陶术生物化合物库目录(2.8MB)

库化合物信息

Excel

SDF

产品描述

262个细胞毒性化合物的特有集合，可用于高通量、高内涵筛选。
包括药物：222个；作用机制和毒理研究已有一定基础。
包括天然产物：89个；活性明确，多为中药有效成分，是极具吸引力的毒理研究小分子。
涉及的靶点超过150个；?涵盖免疫、神经、呼吸、内分泌、心血管等各系统相关疾病。
结构多样，药效显著，可渗透细胞。
NMR、HPLC/LCMS等多种检测技术保证产品结构正确，纯度高，减少假阳性。

化合物库定制

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化合物库组成

DNA/RNA Synthesis (67)

Apoptosis (58)

Autophagy (55)

Antibacterial (46)

Antibiotic (44)

Endogenous Metabolite (28)

Parasite (21)

Nucleoside Antimetabolite/Analog (19)

COX (12)

Dehydrogenase (11)

Antifungal (11)

Topoisomerase (11)

Potassium Channel (11)

DNA Alkylator/Crosslinker (10)

Histamine Receptor (10)

Mitophagy (10)

HSV (9)

Reactive Oxygen Species (8)

HIV Protease (7)

SARS-CoV (7)

AChR (7)

Ferroptosis (6)

Adrenergic Receptor (6)

ribosome (6)

Microtubule Associated (6)

Dopamine Receptor (5)

PPAR (5)

PDE (5)

Influenza Virus (5)

5-HT Receptor (5)

HCV Protease (4)

Antifolate (4)

Calcium Channel (4)

Antifection (4)

BCL (4)

DNA Alkylation (4)

DNA (4)

STAT (4)

Sodium Channel (4)

ATPase (3)

Antioxidant (3)

Virus Protease (3)

HBV (3)

PKC (3)

MAO (3)

NMDAR (3)

mTOR (3)

EGFR (3)

HDAC (3)

NF-κB (3)

Phospholipase (3)

P450 (3)

Thyroid hormone receptor(THR) (2)

Chloride channel (2)

CAT (2)

Transferase (2)

DHFR (2)

Adenosine Receptor (2)

Phosphatase (2)

PKA (2)

Wnt/beta-catenin (2)

Glucocorticoid Receptor (2)

iGluR (2)

Drug Metabolite (2)

Mitochondrial Metabolism (2)

ROS (2)

Opioid Receptor (2)

Lipoxygenase (2)

Norepinephrine (2)

Akt (2)

AChE (2)

HSP (2)

TLR (2)

Casein Kinase (2)

Aromatase (2)

AMPK (2)

TNF (2)

DNA Methyltransferase (2)

Tyrosinase (2)

Monoamine Oxidase (2)

Proteasome (1)

Proton pump (1)

Carbonic Anhydrase (1)

ROR (1)

Amino Acids and Derivatives (1)

p38 MAPK (1)

PI3K (1)

c-Met/HGFR (1)

Cell wall (1)

NADPH (1)

Glutathione Peroxidase (1)

Factor Xa (1)

Tyrosine Kinases (1)

Rho (1)

Serotonin Transporter (1)

VEGFR (1)

TRP/TRPV Channel (1)

ERK (1)

Adiponectin receptor (1)

UGT (1)

MTH1 (1)

Gamma-secretase (1)

CDK (1)

DNA gyrase (1)

PAK (1)

Hedgehog/Smoothened (1)

CXCR (1)

Endothelin Receptor (1)

MMP (1)

PAD (1)

GluR (1)

IGF-1R (1)

DUB (1)

TGF-beta/Smad (1)

P-gp (1)

Prostaglandin Receptor (1)

Trk receptor (1)

Sirtuin (1)

Nrf2 (1)

RSV (1)

IκB/IKK (1)

Reverse Transcriptase (1)

Retinoid Receptor (1)

KLF (1)

CRISPR/Cas9 (1)

GPR (1)

GABA Receptor (1)

HIF (1)

Adenosine deaminase (1)

MEK (1)

FGFR (1)

Complement System (1)

Syk (1)

HMG-CoA Reductase (1)

Ras (1)

Sigma receptor (1)

HIF/HIF Prolyl-Hydroxylase (1)

AhR (1)

CFTR (1)

p53 (1)

NO Synthase (1)

HER (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

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