儿童药物库 | TargetMol

Pediatric Drug Library

产品编号： L9210

儿童药物是指适合儿童特殊体质及需求设计的一类药物，儿童作为特殊群体，在发育和生理上与成人有明显的不同。由于儿童药物的总体需求小于成人药物且研发成本更高，加上临床试验招募和伦理问题，使儿童药物开发过程更加复杂；目前儿童用药远不能满足治疗需求，也存在很多不合理的使用，如药物滥用和超说明书使用等情况，这些都可能对儿童身心带来未知的安全性风险。

保障儿童健康成长对于全人类具有非常重要的意义，开发儿童药物任重道远。TargetMol 收集了972 种儿童药物，所有药物已经被批准用于儿童疾病治疗或处于儿童疾病治疗临床试验中，是儿童药物功能重定位的有用工具。

陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。

产品规格

技术资料

陶术生物化合物库目录(2.8MB)

库化合物信息

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产品描述

972种儿童药物的独特集合，可用于高通量筛选和高内涵筛选；
所有药物已批准上市或处于临床试验中，生物活性和安全性得到验证；
可用于药物功能重定位，以发现新的儿童适应症。
详细的说明书，化合物结构、靶点信息、活性描述等；
NMR和HPLC检测技术保证产品高纯度；
所有化合物现货供应。

化合物库定制

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化合物库组成

Autophagy (191)

Apoptosis (142)

Antibiotic (118)

Antibacterial (111)

Endogenous Metabolite (77)

HIV Protease (53)

DNA/RNA Synthesis (50)

5-HT Receptor (45)

Parasite (44)

Adrenergic Receptor (43)

Histamine Receptor (33)

Dopamine Receptor (29)

COX (29)

Glucocorticoid Receptor (28)

Ferroptosis (25)

SARS-CoV (24)

AChR (24)

Mitophagy (23)

Antifungal (22)

Potassium Channel (22)

Sodium Channel (22)

Reverse Transcriptase (21)

Nucleoside Antimetabolite/Analog (20)

VEGFR (20)

P450 (20)

Topoisomerase (19)

Calcium Channel (18)

c-Kit (18)

Estrogen/progestogen Receptor (17)

Dehydrogenase (16)

RAAS (16)

PDE (16)

PDGFR (16)

HCV Protease (15)

Microtubule Associated (15)

HDAC (14)

JAK (12)

ribosome (12)

FLT (12)

Proteasome (11)

Progesterone Receptor (11)

PPAR (11)

Serotonin Transporter (11)

Antifection (11)

HSV (11)

EGFR (11)

Influenza Virus (11)

GABA Receptor (11)

DNA Alkylator/Crosslinker (10)

Tyrosine Kinases (10)

Reactive Oxygen Species (10)

Androgen Receptor (10)

HBV (9)

Raf (9)

Prostaglandin Receptor (9)

FGFR (9)

Thyroid hormone receptor(THR) (8)

Proton pump (8)

Src (8)

Virus Protease (8)

iGluR (8)

Bcr-Abl (8)

Norepinephrine (8)

ALK (8)

NF-κB (8)

Phospholipase (8)

Transferase (7)

DHFR (7)

PI3K (7)

Antifolate (7)

Gamma-secretase (7)

ROS (7)

DPP-4 (7)

mTOR (7)

Retinoid Receptor (7)

MEK (7)

Thrombin (7)

CFTR (7)

c-Met/HGFR (6)

Adenosine Receptor (6)

Phosphatase (6)

PKC (6)

NMDAR (6)

DNA Alkylation (6)

Akt (6)

AChE (6)

P-gp (6)

TLR (6)

Nrf2 (6)

STAT (6)

c-RET (6)

CAT (5)

MRP (5)

Estrogen Receptor/ERR (5)

Cysteine Protease (5)

MAO (5)

Opioid Receptor (5)

BCL (5)

IL Receptor (5)

Endothelin Receptor (5)

MMP (5)

Trk receptor (5)

TNF (5)

HER (5)

Carbonic Anhydrase (4)

Histone Methyltransferase (4)

LPL Receptor (4)

Factor Xa (4)

PARP (4)

ERK (4)

CDK (4)

Hedgehog/Smoothened (4)

GPR (4)

AMPK (4)

Complement System (4)

DNA Methyltransferase (4)

HMG-CoA Reductase (4)

TAM Receptor (4)

ROS Kinase (4)

NO Synthase (4)

Monoamine Oxidase (4)

S1P Receptor (4)

ATPase (3)

P2Y Receptor (3)

Reductase (3)

Glutathione Peroxidase (3)

GSK-3 (3)

Melatonin Receptor (3)

ABC (3)

TRP/TRPV Channel (3)

ROCK (3)

MT Receptor (3)

Mitochondrial Metabolism (3)

BTK (3)

Molecular Glues (3)

Isocitrate Dehydrogenase (IDH) (3)

Fatty Acid Synthase (3)

GluR (3)

Epigenetic Reader Domain (3)

CaMK (3)

RSV (3)

Neprilysin (3)

Beta Amyloid (3)

Ligand for E3 Ligase (3)

Aromatase (3)

Neurokinin receptor (3)

DNA-PK (2)

CRM1 (2)

Ligands for Target Protein for PROTAC (2)

NADPH (2)

CETP (2)

CaSR (2)

Rho (2)

IRE1 (2)

E1/E2/E3 Enzyme (2)

UGT (2)

Guanylate cyclase (2)

Integrase (2)

Smo (2)

PAK (2)

CCR (2)

Vasopressin Receptor (2)

CXCR (2)

Chk (2)

Xanthine Oxidase (2)

Lipoxygenase (2)

DNA (2)

Indoleamine 2,3-Dioxygenase (IDO) (2)

Interleukin (2)

TGF-beta/Smad (2)

SGLT (2)

Wee1 (2)

Antiviral (2)

HSP (2)

Decarboxylase (2)

GST (2)

ATM/ATR (2)

Hydroxylase (2)

PLK (2)

HIF (2)

Adenosine deaminase (2)

CGRP Receptor (2)

Ras (2)

Sigma receptor (2)

HIF/HIF Prolyl-Hydroxylase (2)

Mdm2 (1)

Chloride channel (1)

NOS (1)

NPC1L1 (1)

Hydrogenase (1)

ROR (1)

Integrin (1)

NEDD8 (1)

Amino Acids and Derivatives (1)

p38 MAPK (1)

YAP (1)

Antioxidant (1)

IFNAR (1)

RAR/RXR (1)

Histone Demethylase (1)

JNK (1)

VDA (1)

GNRH Receptor (1)

Serine Protease (1)

Serine/threonin kinase (1)

FXR (1)

Leukotriene Receptor (1)

Caspase (1)

Aryl Hydrocarbon Receptor (1)

IDO (1)

Annexin A (1)

PAFR (1)

LDL (1)

Drug Metabolite (1)

DNA gyrase (1)

GlyT (1)

Glucosidase (1)

Monoamine Transporter (1)

FAAH (1)

Somatostatin (1)

OX Receptor (1)

ACK (1)

KSP (1)

Aurora Kinase (1)

Thrombopoietin Receptor (1)

IGF-1R (1)

DUB (1)

Telomerase (1)

Beta-Secretase (1)

PGE Synthase (1)

MAPK (1)

Ephrin Receptor (1)

Histone Acetyltransferase (1)

GluCls (1)

Pyroptosis (1)

IκB/IKK (1)

c-Fms (1)

CRISPR/Cas9 (1)

PDK (1)

Oxytocin Receptor (1)

Cannabinoid Receptor (1)

Gap Junction Protein (1)

Platelet aggregation (1)

Anti-infection (1)

NADPH-oxidase (1)

BMI-1 (1)

AhR (1)

NOD-like Receptor (NLR) (1)

PKM (1)

Kinesin (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

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