疼痛相关化合物库

Pain-Related Compound Library

产品编号： L2690

疼痛是一种与实际或潜在的组织损伤相关的不愉快的感觉和情绪情感体验，或与此相似的经历；作为六大生命体征之一，疼痛与呼吸、脉搏、血压、体温等同样重要，反映了身体的健康状态。疼痛按持续时间分为急性疼痛、慢性疼痛；按照病因分为伤害性疼痛和神经病理性疼痛；按感受系统分类表层疼痛、深层疼痛；还可根据来源分为内脏痛和体表痛。

疼痛的产生机制是一个复杂的过程，涉及多个层面，包括生理、心理和神经生物学方面，疼痛主要的机制包括：痛觉感受器的激活，痛觉感受器是分布在皮肤、内脏、骨骼肌和关节等部位的专门感知有害刺激的感觉神经末梢。致痛物质的释放：当组织损伤时，会释放多种致痛物质，如组胺、缓激肽、5-羟色胺、乙酰胆碱、前列腺素等，这些物质能激活痛觉感受器。此外还包括神经信号传导、中枢调控、心理因素等等

TargetMol收集了2780种疼痛相关活性化合物及靶向疼痛相关靶点的化合物，可用于疼痛相关研究。

陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。

产品规格

技术资料

陶术生物化合物库目录(2.8MB)

库化合物信息

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产品描述

2780种疼痛相关化合物的独特集合，可用于高通量筛选和高内涵筛选；
结构多样，具有良好的细胞渗透性；
详细的说明书，化合物结构、靶点信息、活性描述等；
NMR、HPLC/LCMS等多种检测技术保证产品结构正确，纯度高，减少假阳性。

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化合物库组成

5-HT Receptor (409)

COX (280)

Calcium Channel (229)

Potassium Channel (217)

Histamine Receptor (191)

Sodium Channel (176)

Autophagy (171)

GABA Receptor (167)

Apoptosis (154)

AChR (147)

TRP/TRPV Channel (136)

Dopamine Receptor (117)

p38 MAPK (110)

ERK (107)

Prostaglandin Receptor (106)

Opioid Receptor (101)

NMDAR (95)

Endogenous Metabolite (88)

Raf (82)

Adrenergic Receptor (78)

NF-κB (78)

Antibacterial (59)

JNK (58)

MAPK (58)

Ras (52)

Kras (50)

MEK (48)

iGluR (45)

Parasite (39)

Akt (34)

TNF (34)

S6 Kinase (32)

P450 (31)

CDK (30)

Neurokinin receptor (28)

Reactive Oxygen Species (27)

Norepinephrine (27)

Serotonin Transporter (26)

Lipoxygenase (26)

Endothelin Receptor (25)

NO Synthase (25)

PPAR (24)

VEGFR (21)

Src (20)

Bradykinin Receptor (20)

Caspase (19)

Antibiotic (19)

IL Receptor (18)

GluR (17)

HER (17)

NOS (16)

Ferroptosis (16)

GPR (16)

Rho (15)

PKC (15)

EGFR (15)

Antifungal (14)

PKA (14)

Antioxidant (13)

GSK-3 (13)

Influenza Virus (13)

Cannabinoid Receptor (13)

Sigma receptor (13)

ATPase (12)

P2X Receptor (12)

BCL (12)

Aurora Kinase (12)

mTOR (12)

DNA/RNA Synthesis (12)

HIV Protease (11)

PI3K (11)

Mitophagy (11)

PDE (11)

Drug Metabolite (11)

AChE (11)

STAT (11)

Chloride channel (10)

ROS (10)

PDGFR (10)

FAAH (10)

IGF-1R (10)

AMPK (10)

Phospholipase (10)

Virus Protease (9)

ROCK (9)

TGF-beta/Smad (9)

PGE Synthase (9)

MNK (9)

P-gp (9)

Casein Kinase (9)

FLT (9)

c-Kit (9)

MLK (9)

Wnt/beta-catenin (8)

PARP (8)

MAO (8)

Interleukin (8)

Carbonic Anhydrase (7)

Estrogen/progestogen Receptor (7)

MRP (7)

Topoisomerase (7)

Bcr-Abl (7)

JAK (7)

MMP (7)

SARS-CoV (7)

IκB/IKK (7)

Histone Methyltransferase (6)

HCV Protease (6)

Dehydrogenase (6)

RAAS (6)

HBV (6)

Glucocorticoid Receptor (6)

Antifection (6)

CaMK (6)

Trk receptor (6)

Beta Amyloid (6)

c-RET (6)

Thrombin (6)

Transferase (5)

NADPH (5)

Glutathione Peroxidase (5)

TOPK (5)

Phosphatase (5)

ABC (5)

Serine/threonin kinase (5)

LDL (5)

Mitochondrial Metabolism (5)

HSV (5)

TLR (5)

transporter (5)

Nrf2 (5)

ASK (5)

HDAC (5)

FGFR (5)

CGRP Receptor (5)

SGK (5)

Syk (5)

Anti-infection (5)

Tyrosinase (5)

FAK (5)

LTR (4)

Adenosine Receptor (4)

Na+/Ca2+ Exchanger (4)

Reductase (4)

DYRK (4)

Progesterone Receptor (4)

Myosin (4)

Acyltransferase (4)

Antiviral (4)

Platelet aggregation (4)

NOD (4)

p53 (4)

Transaminase (3)

Lipase (3)

GTPase (3)

Estrogen Receptor/ERR (3)

Tyrosine Kinases (3)

Serine Protease (3)

IAP (3)

PAFR (3)

Gamma-secretase (3)

AAK1 (AP2 associated kinase 1) (3)

BTK (3)

Monoamine Transporter (3)

CCR (3)

Chk (3)

cAMP (3)

Epigenetic Reader Domain (3)

DNA (3)

Androgen Receptor (3)

Beta-Secretase (3)

ALK (3)

c-Fms (3)

KLF (3)

IRAK (3)

HMG-CoA Reductase (3)

AhR (3)

Proteasome (2)

Proton pump (2)

Amino Acids and Derivatives (2)

c-Met/HGFR (2)

IFNAR (2)

GNRH Receptor (2)

Pim (2)

cell cycle arrest (2)

FXR (2)

Leukotriene Receptor (2)

Aryl Hydrocarbon Receptor (2)

CSF-1R (2)

Immunology/Inflammation related (2)

UGT (2)

GlyT (2)

DNA Alkylation (2)

PAK (2)

Epoxide Hydrolase (2)

ACK (2)

HSP (2)

STING (2)

LRRK2 (2)

Free radical scavengers (2)

GST (2)

PDK (2)

Hydroxylase (2)

Gap Junction Protein (2)

NADPH-oxidase (2)

DNA Methyltransferase (2)

Protease-activated Receptor (2)

NOD-like Receptor (NLR) (2)

PD-1/PD-L1 (2)

Melanin-concentrating Hormone Receptor (MCHR) (1)

Apelin receptor (1)

Taste receptor (1)

PROTACs (1)

Adenylyl cyclase (1)

Monocarboxylate transporter (1)

Integrin (1)

MyD88 (1)

LPL Receptor (1)

Arrestin (1)

BACE (1)

RAR/RXR (1)

gp120/CD4 (1)

Tie-2 (1)

Melatonin Receptor (1)

OCT (1)

c-Myc (1)

N-Acetylglucosaminyltransferase (1)

CaSR (1)

Antifolate (1)

Cysteine Protease (1)

LIM Kinase (1)

Glucokinase (1)

PYK2 (1)

Annexin A (1)

FLAP (1)

RIP kinase (1)

GRK (1)

MT Receptor (1)

Glucagon Receptor (1)

DNA gyrase (1)

Na-K-Cl cotransporter (1)

Glucosidase (1)

Anion Exchanger (1)

PROTAC Linker (1)

Stearoyl-CoA Desaturase (SCD) (1)

Vasopressin Receptor (1)

PTEN (1)

OX Receptor (1)

Indoleamine 2,3-Dioxygenase (IDO) (1)

BCRP (1)

MRGPR (1)

Sirtuin (1)

Ephrin Receptor (1)

GluCls (1)

HuR (1)

PAI-1 (1)

MELK (1)

RSV (1)

Hippo pathway (1)

GPX (1)

Retinoid Receptor (1)

Aromatase (1)

RXFP receptor (1)

DAPK (1)

BMI-1 (1)

cholecystokinin (1)

Microtubule Associated (1)

HIF/HIF Prolyl-Hydroxylase (1)

CFTR (1)

Imidazoline Receptor (1)

Kinesin (1)

S1P Receptor (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

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