口服活性化合物库

Orally Active Compound Library

产品编号： L9850

口服给药是临床给药尤其是长期用药的常用给药方式，也是安全、方便、经济的给药方法；口服生物利用度是药物经胃肠道黏膜吸收，经过肝脏进入体循环血液中的药量占口服剂量的百分比；口服生物利用度高的药物，较低剂量即可达到疗效，有效降低毒副作用；而口服生物利用度过低时，药理活性好的化合物也无法在靶部位充分的暴露，由此造成治疗的失败或者剂量过高产生较大的毒副作用，导致药物开发失败，限制了应用。 TargetMol 精心收集了 3160 种公开报道具有口服活性的化合物，可以用于药物再利用及口服活性药物的开发。

陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。

产品规格

技术资料

陶术生物化合物库目录(2.8MB)

库化合物信息

Excel

SDF

产品描述

3160种口服活性化合物独特集合，可用于高通量筛选和高内涵筛选；
部分药物已批准上市或处于临床试验中，生物活性和安全性得到验证；
详细的说明书，化合物结构、靶点信息、活性描述等；
NMR和HPLC检测技术保证产品高纯度；
所有化合物现货供应。

化合物库定制

我们的化合物库可以灵活定制！了解更多

化合物库咨询

化合物库组成

Apoptosis (264)

Autophagy (260)

Antibacterial (177)

Antibiotic (157)

5-HT Receptor (151)

Adrenergic Receptor (106)

Histamine Receptor (100)

Dopamine Receptor (94)

COX (81)

AChR (72)

HIV Protease (66)

VEGFR (65)

EGFR (57)

DNA/RNA Synthesis (56)

Potassium Channel (53)

Parasite (52)

Sodium Channel (52)

Calcium Channel (49)

PDE (49)

PDGFR (48)

P450 (47)

CDK (46)

SARS-CoV (46)

FLT (46)

c-Kit (43)

Estrogen/progestogen Receptor (41)

Glucocorticoid Receptor (41)

RAAS (38)

Dehydrogenase (37)

HCV Protease (33)

PI3K (33)

JAK (33)

Src (32)

Estrogen Receptor/ERR (32)

FGFR (32)

BTK (29)

Antifungal (28)

c-Met/HGFR (28)

Bcr-Abl (27)

PPAR (26)

Serotonin Transporter (26)

Ferroptosis (25)

Reverse Transcriptase (25)

HDAC (25)

Proteasome (24)

p38 MAPK (24)

HBV (24)

Topoisomerase (24)

Androgen Receptor (24)

Histone Methyltransferase (23)

Epigenetic Reader Domain (23)

Endogenous Metabolite (23)

GPR (23)

Microtubule Associated (23)

Raf (22)

GluR (22)

Norepinephrine (22)

Prostaglandin Receptor (22)

ALK (22)

GABA Receptor (22)

TRP/TRPV Channel (21)

Influenza Virus (21)

HER (21)

Phosphatase (20)

Mitophagy (20)

Tyrosine Kinases (20)

PARP (20)

NF-κB (20)

Progesterone Receptor (18)

iGluR (18)

mTOR (18)

Transferase (17)

Adenosine Receptor (17)

Opioid Receptor (17)

Integrin (16)

ERK (16)

ROS (16)

DPP-4 (16)

MAPK (16)

MEK (16)

Proton pump (15)

Nucleoside Antimetabolite/Analog (15)

Trk receptor (15)

TNF (15)

LPL Receptor (14)

Factor Xa (14)

GSK-3 (14)

Reactive Oxygen Species (14)

MMP (14)

Akt (14)

P-gp (14)

Antiviral (14)

Kras (14)

c-Fms (14)

c-RET (14)

Syk (14)

TAM Receptor (14)

Thrombin (14)

S1P Receptor (14)

Monoamine Oxidase (14)

ROCK (13)

NMDAR (13)

Endothelin Receptor (13)

SGLT (13)

Retinoid Receptor (13)

STAT (13)

Carbonic Anhydrase (12)

Reductase (12)

HSV (12)

CCR (12)

CXCR (12)

AChE (12)

HSP (12)

Beta Amyloid (12)

HIF/HIF Prolyl-Hydroxylase (12)

ATPase (11)

MAO (11)

Aurora Kinase (11)

Lipoxygenase (11)

Interleukin (11)

Acyltransferase (11)

ribosome (11)

AMPK (11)

Cannabinoid Receptor (11)

ROS Kinase (11)

Thyroid hormone receptor(THR) (10)

DHFR (10)

ADC Cytotoxin (10)

MRP (10)

Wnt/beta-catenin (10)

PKC (10)

CSF-1R (10)

Gamma-secretase (10)

Mitochondrial Metabolism (10)

IL Receptor (10)

ATM/ATR (10)

Phospholipase (10)

Virus Protease (9)

Glucagon Receptor (9)

Guanylate cyclase (9)

Fatty Acid Synthase (9)

IGF-1R (9)

TGF-beta/Smad (9)

Neurokinin receptor (9)

ROR (8)

NADPH (8)

Histone Demethylase (8)

E1/E2/E3 Enzyme (8)

P2X Receptor (8)

DNA gyrase (8)

Hedgehog/Smoothened (8)

RSV (8)

Ligand for E3 Ligase (8)

FAK (8)

CFTR (8)

DNA Alkylator/Crosslinker (7)

P2Y Receptor (7)

PKA (7)

Antifolate (7)

Serine/threonin kinase (7)

Leukotriene Receptor (7)

Caspase (7)

Vasopressin Receptor (7)

OX Receptor (7)

Xanthine Oxidase (7)

Beta-Secretase (7)

TLR (7)

Aromatase (7)

Hydroxylase (7)

PLK (7)

Complement System (7)

IRAK (7)

HMG-CoA Reductase (7)

Sigma receptor (7)

NO Synthase (7)

Mdm2 (6)

LTR (6)

BACE (6)

PERK (6)

Glutathione Peroxidase (6)

ABC (6)

GNRH Receptor (6)

Pim (6)

Cysteine Protease (6)

FXR (6)

Antifection (6)

Smo (6)

BCL (6)

DNA Alkylation (6)

CaMK (6)

transporter (6)

ASK (6)

Casein Kinase (6)

GHSR (6)

DNA Methyltransferase (6)

Ras (6)

PD-1/PD-L1 (6)

DNA-PK (5)

Serine Protease (5)

Isocitrate Dehydrogenase (IDH) (5)

Stearoyl-CoA Desaturase (SCD) (5)

Chk (5)

Aminopeptidase (5)

Ephrin Receptor (5)

HIF (5)

NADPH-oxidase (5)

NOS (4)

YAP (4)

Lipase (4)

Melatonin Receptor (4)

IAP (4)

Neuropeptide Y Receptor (4)

PAK (4)

FAAH (4)

DNA (4)

DUB (4)

Indoleamine 2,3-Dioxygenase (IDO) (4)

PGE Synthase (4)

Porcupine (4)

PAI-1 (4)

Neprilysin (4)

cholecystokinin (4)

Protease-activated Receptor (4)

AhR (4)

p53 (4)

Monocarboxylate transporter (3)

CRM1 (3)

Antioxidant (3)

IFNAR (3)

CETP (3)

JNK (3)

TOPK (3)

CaSR (3)

Liver X Receptor (3)

Glucokinase (3)

Annexin A (3)

FLAP (3)

RIP kinase (3)

Drug Metabolite (3)

MT Receptor (3)

Monoamine Transporter (3)

Molecular Glues (3)

PAD (3)

Epoxide Hydrolase (3)

Thrombopoietin Receptor (3)

Mucin (3)

OXPHOS (3)

Free radical scavengers (3)

IκB/IKK (3)

GST (3)

LPA Receptor (3)

PI4K (3)

Discoidin Domain Receptor (DDR) (3)

NOD (3)

S6 Kinase (3)

Melanin-concentrating Hormone Receptor (MCHR) (2)

advanced glycation end products (2)

PROTACs (2)

MALT (2)

NEDD8 (2)

Ligands for Target Protein for PROTAC (2)

Tie-2 (2)

Rho (2)

Hck (2)

Vitamin (2)

Glutaminase (2)

Aryl Hydrocarbon Receptor (2)

IDO (2)

SIK (2)

IRE1 (2)

PAFR (2)

GlyT (2)

Hexokinase (2)

Integrase (2)

Bradykinin Receptor (2)

Telomerase (2)

Lipid (2)

MNK (2)

OAT (2)

STING (2)

LRRK2 (2)

Nrf2 (2)

Hippo pathway (2)

Acetyl-CoA Carboxylase (2)

PDK (2)

Adenosine deaminase (2)

CGRP Receptor (2)

SGK (2)

BMI-1 (2)

NOD-like Receptor (NLR) (2)

MLK (2)

Imidazoline Receptor (2)

Kinesin (2)

Chloride channel (1)

Taste receptor (1)

CAT (1)

GSNOR (1)

NPC1L1 (1)

CD38 (1)

Amino Acids and Derivatives (1)

Na+/Ca2+ Exchanger (1)

DYRK (1)

Cell wall (1)

Necroptosis (1)

GTPase (1)

c-Myc (1)

Galectin (1)

Neurotensin Receptor (1)

NAMPT (1)

PYK2 (1)

FOXO1 (1)

Prolyl Endopeptidase (PREP) (1)

Myosin (1)

Adiponectin receptor (1)

UGT (1)

Haspin Kinase (1)

LDL (1)

GRK (1)

PACAP (1)

AAK1 (AP2 associated kinase 1) (1)

Na-K-Cl cotransporter (1)

Glucosidase (1)

PROTAC Linker (1)

HCN Channel (1)

Angiotensin-converting Enzyme (ACE) (1)

Somatostatin (1)

ACK (1)

cAMP (1)

ATP Citrate Lyase (1)

Wee1 (1)

BCRP (1)

Survivin (1)

GPCR19 (1)

Sirtuin (1)

Histone Acetyltransferase (1)

Pyroptosis (1)

Methionine Adenosyltransferase (MAT) (1)

GPX (1)

Melanocortin Receptor (1)

CRISPR/Cas9 (1)

Oxytocin Receptor (1)

RXFP receptor (1)

Gap Junction Protein (1)

Platelet aggregation (1)

Anti-infection (1)

Tyrosinase (1)

p97 (1)

PKM (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

注册成功