核受体化合物库

Nuclear Receptor Compound Library

产品编号： L1510

核受体是细胞内一类区别于膜受体的蛋白，它们与相应配体结合后，能够直接与基因组DNA 结合并调节相邻基因表达，因此这类受体被归类为转录因子。核受体在胚胎发育和机体内环境平衡中发挥关键作用。近年来，核受体家族在代谢性疾病领域受到广泛的关注，已有研究证明，它们与糖尿病、脂肪肝等疾病的发生发展密切相关，也被称为代谢性核受体。

TargetMol 汇集了631 种有文献报道的核受体相关化合物，适用于核受体相关信号通路及疾病研究，可用于高通量筛选和高内涵筛选。

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产品规格

技术资料

陶术生物化合物库目录(2.8MB)

库化合物信息

Excel

SDF

产品描述

631个核受体作用化合物的独特集合，可用于高通量筛选和高内涵筛选；
提供产品的来源、化学信息和生物学信息，为筛选提供理论方向和研究基础；
结构多样，药效显著，可渗透细胞；
NMR和HPLC技术保证产品高纯度。

化合物库定制

我们的化合物库可以灵活定制！了解更多

化合物库咨询

化合物库组成

PPAR (137)

Estrogen/progestogen Receptor (107)

Estrogen Receptor/ERR (93)

Glucocorticoid Receptor (73)

Autophagy (72)

Androgen Receptor (71)

Endogenous Metabolite (54)

Retinoid Receptor (46)

Apoptosis (37)

Progesterone Receptor (30)

Thyroid hormone receptor(THR) (23)

FXR (23)

ROR (22)

AhR (20)

Liver X Receptor (18)

COX (16)

Antibacterial (15)

NF-κB (14)

P450 (12)

Aryl Hydrocarbon Receptor (10)

ADC Cytotoxin (8)

Reactive Oxygen Species (7)

Ferroptosis (6)

Antifungal (6)

TSH Receptor (6)

GPR (6)

RAR/RXR (5)

IL Receptor (5)

Akt (5)

AMPK (5)

Potassium Channel (5)

Antibiotic (5)

Reductase (4)

Parasite (4)

Adrenergic Receptor (4)

Drug Metabolite (4)

BCL (4)

MMP (4)

Prostaglandin Receptor (4)

GPCR19 (4)

Influenza Virus (4)

TNF (4)

Tyrosinase (4)

p38 MAPK (3)

Mitophagy (3)

Calcium Channel (3)

Annexin A (3)

Mitochondrial Metabolism (3)

ROS (3)

Epigenetic Reader Domain (3)

Lipoxygenase (3)

Interleukin (3)

SARS-CoV (3)

Nrf2 (3)

Cannabinoid Receptor (3)

p53 (3)

NO Synthase (3)

HIV Protease (2)

NOS (2)

Antioxidant (2)

JNK (2)

Phosphatase (2)

GSK-3 (2)

Virus Protease (2)

ABC (2)

Wnt/beta-catenin (2)

PARP (2)

VEGFR (2)

TRP/TRPV Channel (2)

ERK (2)

PDE (2)

Smo (2)

Sirtuin (2)

transporter (2)

Aromatase (2)

GABA Receptor (2)

AChR (2)

Proteasome (1)

Adenylyl cyclase (1)

Carbonic Anhydrase (1)

Histone Methyltransferase (1)

HCV Protease (1)

Dehydrogenase (1)

c-Met/HGFR (1)

IFNAR (1)

RAAS (1)

PERK (1)

Histamine Receptor (1)

Glutathione Peroxidase (1)

gp120/CD4 (1)

Melatonin Receptor (1)

PKA (1)

GNRH Receptor (1)

MRP (1)

HBV (1)

Cysteine Protease (1)

Nucleoside Antimetabolite/Analog (1)

Leukotriene Receptor (1)

Glucokinase (1)

Caspase (1)

PKC (1)

MAO (1)

Immunology/Inflammation related (1)

Topoisomerase (1)

FLAP (1)

Gamma-secretase (1)

LDL (1)

Glucagon Receptor (1)

Phosphorylase (1)

Glucosidase (1)

Antifection (1)

Opioid Receptor (1)

Fatty Acid Synthase (1)

PGC-1α (1)

Epoxide Hydrolase (1)

GluR (1)

CaMK (1)

DNA (1)

mTOR (1)

EGFR (1)

Lipid (1)

DNA/RNA Synthesis (1)

P-gp (1)

HSP (1)

STING (1)

Histone Acetyltransferase (1)

STAT (1)

Phospholipase (1)

Hydroxylase (1)

Complement System (1)

FLT (1)

c-Kit (1)

Sodium Channel (1)

DNA Methyltransferase (1)

HMG-CoA Reductase (1)

TAM Receptor (1)

Thrombin (1)

HIF/HIF Prolyl-Hydroxylase (1)

HER (1)

S1P Receptor (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

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