神经保护化合物库

Neuroprotective Compound Library

产品编号： L2640

神经保护（Neuroprotection）是指通过各种机制和手段来防止神经元受到损伤或促进神经元的修复，从而保护神经系统功能的过程。这一领域的研究主要集中在防止神经元凋亡、减少炎症反应、减少氧化应激和促进神经再生等方面。神经保护在许多神经退行性疾病（如阿尔茨海默病、帕金森病、多发性硬化症）以及急性神经损伤（如中风和脊髓损伤）中具有重要意义。研究揭示了多个关键靶点，如抗氧化，神经营养因子，钙离子通道等在预防神经元损伤、促进神经再生以及对抗神经退行性疾病方面展现出潜力。

TargetMol神经保护化合物库收集了990种具有神经保护活性及潜在的神经保护活性化合物，可用于神经保护相关的药物研发，神经保护相关机制探索。

陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。

产品规格

技术资料

陶术生物化合物库目录(2.8MB)

库化合物信息

Excel

SDF

产品描述

990种神经保护相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
靶点包括BDNF、Calcium Channel、Sodium Channel、NMDAR/TRPM4等；
结构多样，药效显著，可渗透细胞；
详细的说明书，化合物结构、靶点信息、IC50值、活性描述等；
NMR、HPLC/LCMS等多种检测技术保证产品结构正确，纯度高，减少假阳性。

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化合物库组成

Calcium Channel (112)

Sodium Channel (102)

Wnt/beta-catenin (85)

GSK-3 (66)

Potassium Channel (55)

iGluR (45)

NMDAR (43)

GluR (40)

Autophagy (36)

Apoptosis (36)

GABA Receptor (34)

AMPK (27)

CDK (21)

NO Synthase (21)

AChR (19)

PARP (13)

NOS (11)

Dopamine Receptor (11)

Reactive Oxygen Species (9)

Mitophagy (8)

5-HT Receptor (8)

Adenosine Receptor (7)

Histamine Receptor (7)

Parasite (7)

ERK (7)

Adrenergic Receptor (7)

Akt (7)

NF-κB (7)

P450 (7)

TRP/TRPV Channel (6)

MAO (6)

PDE (6)

Beta Amyloid (6)

Monoamine Oxidase (6)

Src (5)

COX (5)

EGFR (5)

Endogenous Metabolite (5)

S6 Kinase (5)

Microtubule Associated (5)

Carbonic Anhydrase (4)

RAAS (4)

Phosphatase (4)

PKA (4)

PKC (4)

Glucocorticoid Receptor (4)

Mitochondrial Metabolism (4)

ROS (4)

mTOR (4)

Antibacterial (4)

Lipid (4)

MAPK (4)

Porcupine (4)

Casein Kinase (4)

Sigma receptor (4)

HIV Protease (3)

Estrogen/progestogen Receptor (3)

Antioxidant (3)

Virus Protease (3)

PPAR (3)

Serotonin Transporter (3)

E1/E2/E3 Enzyme (3)

Chk (3)

Aurora Kinase (3)

Norepinephrine (3)

AChE (3)

P-gp (3)

MEK (3)

FLT (3)

Antibiotic (3)

HIF/HIF Prolyl-Hydroxylase (3)

HER (3)

Chloride channel (2)

Ferroptosis (2)

PI3K (2)

LPL Receptor (2)

Na+/Ca2+ Exchanger (2)

DYRK (2)

JNK (2)

Estrogen Receptor/ERR (2)

Caspase (2)

Bcr-Abl (2)

Gamma-secretase (2)

Guanylate cyclase (2)

Opioid Receptor (2)

HSV (2)

IL Receptor (2)

Lipoxygenase (2)

Epigenetic Reader Domain (2)

CaMK (2)

Interleukin (2)

TGF-beta/Smad (2)

Beta-Secretase (2)

LRRK2 (2)

Trk receptor (2)

GPR (2)

FGFR (2)

TNF (2)

AhR (2)

Imidazoline Receptor (2)

S1P Receptor (2)

Proteasome (1)

ATPase (1)

Adenylyl cyclase (1)

Piezo Channel (1)

HCV Protease (1)

YAP (1)

Antifungal (1)

Arrestin (1)

PERK (1)

GTPase (1)

Progesterone Receptor (1)

MRP (1)

Tyrosine Kinases (1)

Serine/threonin kinase (1)

Cysteine Protease (1)

NAMPT (1)

Glucokinase (1)

VEGFR (1)

ROCK (1)

Aryl Hydrocarbon Receptor (1)

Immunology/Inflammation related (1)

Topoisomerase (1)

UGT (1)

Drug Metabolite (1)

P2X Receptor (1)

Monoamine Transporter (1)

BCL (1)

HCN Channel (1)

DPP-4 (1)

Fatty Acid Synthase (1)

PDGFR (1)

JAK (1)

Stearoyl-CoA Desaturase (SCD) (1)

MMP (1)

OX Receptor (1)

IGF-1R (1)

ATP Citrate Lyase (1)

Prostaglandin Receptor (1)

Pyroptosis (1)

Methionine Adenosyltransferase (MAT) (1)

Influenza Virus (1)

GST (1)

Acetyl-CoA Carboxylase (1)

Retinoid Receptor (1)

STAT (1)

HDAC (1)

PDK (1)

Cannabinoid Receptor (1)

NOD (1)

HMG-CoA Reductase (1)

cholecystokinin (1)

TAM Receptor (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

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