神经再生化合物库

Neural Regeneration Compound Library

产品编号： L7700

众所周知，神经系统疾病是严重危害人类健康的疾病之一，神经损伤后的治疗、再生和功能恢复是医学领域的历史性难题。虽然临床上针对神经损伤及神经退行性疾病采用了药物、手术、组织工程、针灸等多种手段，但目前仍缺乏明确有效的治疗措施，要想提高神经损伤治疗效果，必须弄清神经再生相关机制。近些年来，随着神经再生研究的不断深入，人们逐渐认识到， Rho-ROCK、Notch、MAPK、Wnt/β-catenin、mTOR、Eph-ephrin 等信号通路与神经再生密切相关。神经系统损伤后往往会产生多种应激信号，究竟哪些或哪种信号会对神经再生起到更为深刻的影响尚未可知。

TargetMol 神经再生化合物库把众多与神经再生相关的信号通路的激动剂或抑制剂集合在一起，是筛选神经再生诱导剂的有效工具。

陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。

产品规格

技术资料

陶术生物化合物库目录(2.8MB)

库化合物信息

Excel

SDF

产品描述

524种神经再生相关化合物的独特集合，可用于高通量筛选和高内涵筛选；
作用于多个信号通路，如Notch、MAPK、Wnt/β-catenin、mTOR,等等；
通过前期临床研究和临床实验，生物活性和安全性已经得到验证；
其中一些抑制剂已得到FDA批准上市；
详细的说明书，化合物结构、靶点信息、IC50值、活性描述等；
NMR和HPLC检测技术保证产品高纯度；
所有化合物现货供应。

化合物库定制

我们的化合物库可以灵活定制！了解更多

化合物库咨询

化合物库组成

PI3K (150)

Apoptosis (111)

Autophagy (107)

Akt (80)

mTOR (76)

p38 MAPK (74)

Wnt/beta-catenin (64)

ERK (37)

ROCK (34)

MAPK (34)

DNA-PK (28)

ATM/ATR (23)

JNK (20)

Gamma-secretase (20)

NF-κB (20)

Endogenous Metabolite (16)

Rho (13)

PKC (13)

PARP (12)

Antibacterial (12)

S6 Kinase (12)

Caspase (11)

CDK (11)

Src (10)

PKA (10)

Parasite (10)

Ras (10)

VEGFR (9)

Reactive Oxygen Species (9)

Casein Kinase (9)

MEK (9)

AMPK (8)

HIV Protease (6)

Antifungal (6)

Raf (6)

COX (6)

PI4K (6)

TNF (6)

Mitophagy (5)

GSK-3 (5)

BCL (5)

DNA/RNA Synthesis (5)

Beta Amyloid (5)

STAT (5)

HDAC (5)

Antibiotic (5)

Ferroptosis (4)

PERK (4)

PPAR (4)

Bcr-Abl (4)

IL Receptor (4)

Aurora Kinase (4)

TGF-beta/Smad (4)

Porcupine (4)

Ephrin Receptor (4)

ASK (4)

Influenza Virus (4)

Carbonic Anhydrase (3)

Serine Protease (3)

Calcium Channel (3)

Glucosidase (3)

PDGFR (3)

MMP (3)

Epigenetic Reader Domain (3)

Lipoxygenase (3)

Interleukin (3)

P-gp (3)

Antiviral (3)

PDK (3)

GABA Receptor (3)

P450 (3)

SGK (3)

FLT (3)

HCV Protease (2)

c-Met/HGFR (2)

Antioxidant (2)

Adenosine Receptor (2)

Phosphatase (2)

Virus Protease (2)

Serine/threonin kinase (2)

Adrenergic Receptor (2)

GRK (2)

JAK (2)

IGF-1R (2)

EGFR (2)

TLR (2)

Trk receptor (2)

transporter (2)

ALK (2)

c-Fms (2)

PLK (2)

Cannabinoid Receptor (2)

c-Kit (2)

Sodium Channel (2)

FAK (2)

NO Synthase (2)

ATPase (1)

DHFR (1)

Integrin (1)

Estrogen/progestogen Receptor (1)

Arginase (1)

BACE (1)

Lipase (1)

RAAS (1)

Tie-2 (1)

MRP (1)

HBV (1)

Tyrosine Kinases (1)

Hck (1)

FXR (1)

Aryl Hydrocarbon Receptor (1)

Immunology/Inflammation related (1)

Topoisomerase (1)

Myosin (1)

PDE (1)

Drug Metabolite (1)

Mitochondrial Metabolism (1)

BTK (1)

Antifection (1)

MAGL (1)

DNA Alkylation (1)

HSV (1)

PTEN (1)

Chk (1)

ACK (1)

DNA (1)

CaMK (1)

BCRP (1)

Beta-Secretase (1)

AChE (1)

MNK (1)

LRRK2 (1)

Nrf2 (1)

MELK (1)

Methionine Adenosyltransferase (MAT) (1)

IκB/IKK (1)

Aromatase (1)

CRISPR/Cas9 (1)

GPR (1)

5-HT Receptor (1)

FGFR (1)

Potassium Channel (1)

AhR (1)

Kinesin (1)

S1P Receptor (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

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