天然产物库 | TargetMol

Natural Product Library

产品编号： L6010

天然产物在化学结构和生物活性多样性方面的优势，使其在新药研发中具有不可替代的重要地位。近年来提取分离和结构鉴定技术的快速发展, 大大提高了从天然产物中开发新药的效率和成功率。据统计，1981年至 2019年所有上市的药物中，有近2/3的药物在不同程度上都与天然产物相关。我国近50年自研成功的新药90%以上与天然产物有关。

然而，长期困扰天然产物药物筛选的问题之一是，得到天然产物苗头化合物进行后继的药理实验时，天然产物的成本太高。为了一定程度上帮助研发人员避免这个问题，TargetMol 推出L6010天然产物库，收集 3837 种天然产物单体，广泛涉及1800种植物来源。在筛得阳性化合物以后，您从自然界或者天然产物全合成中得到此产品大包装的难度更小，更能满足您对于苗头化合物进行深入研究时成本控制的需求。

陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。

产品规格

技术资料

陶术生物化合物库目录(2.8MB)

库化合物信息

Excel

SDF

产品描述

3837种天然产物的独特集合，可用于高通量筛选和高内涵筛选；
提供产品的生物学信息和药物学信息，为筛选提供理论方向和研究基础；
来源清晰：精选来自动物、植物、微生物的已知活性天然产物；更具体到植物种属，并标注准确英文名与拉丁名，方便您的后期研究确证；
结构多样性好：含黄酮类、生物碱类在内的多种化合物类型，拥有详细的分类信息；
NMR、HPLC/LCMS等多种检测技术保证产品结构正确，纯度高，减少假阳性。

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化合物库组成

Endogenous Metabolite (1016)

Apoptosis (375)

Antibacterial (339)

Autophagy (237)

NF-κB (166)

Antibiotic (147)

Antioxidant (130)

Antifungal (127)

Reactive Oxygen Species (102)

COX (92)

Parasite (85)

Cytochromes P450 (64)

Influenza Virus (64)

DNA/RNA Synthesis (59)

AChR (58)

TNF (57)

GABA Receptor (49)

HIV Protease (48)

Cholinesterase (ChE) (47)

NO Synthase (45)

Calcium Channel (44)

Caspase (42)

Akt (42)

PPAR (41)

ERK (41)

p38 MAPK (40)

IL Receptor (39)

Anti-infection (39)

AMPK (36)

Virus Protease (35)

STAT (35)

Ferroptosis (34)

Tyrosinase (34)

MMP (31)

PKC (30)

Topoisomerase (29)

ROS (29)

Estrogen/progestogen Receptor (28)

Dehydrogenase (28)

PI3K (28)

Nrf2 (28)

5-HT Receptor (28)

Estrogen Receptor/ERR (27)

Lipoxygenase (27)

Microtubule Associated (27)

HSV (26)

Mitophagy (24)

BCL (24)

Potassium Channel (24)

TRP/TRPV Channel (23)

Adrenergic Receptor (23)

NOS (22)

ADC Cytotoxin (22)

JNK (22)

ATPase (21)

Antiviral (21)

Beta Amyloid (21)

Sodium Channel (21)

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PARP (19)

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P-gp (19)

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Antifection (18)

HBV (17)

Drug Metabolite (17)

EGFR (17)

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HDAC (17)

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Immunology/Inflammation related (16)

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Interleukin (15)

ribosome (15)

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Amino Acids and Derivatives (14)

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Phosphatase (14)

MAO (14)

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mTOR (14)

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RAAS (9)

Histamine Receptor (9)

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transporter (9)

IκB/IKK (9)

GPR (9)

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Androgen Receptor (8)

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Gamma-secretase (7)

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Proton pump (3)

CAT (3)

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Progesterone Receptor (3)

Serotonin Transporter (3)

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cell cycle arrest (3)

Cysteine Protease (3)

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Smo (3)

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Retinoid Receptor (3)

Syk (3)

DNA Methyltransferase (3)

S6 Kinase (3)

Imidazoline Receptor (3)

HER (3)

DHFR (2)

Histone Methyltransferase (2)

DYRK (2)

Lipase (2)

OCT (2)

Pim (2)

Antifolate (2)

Leukotriene Receptor (2)

Glucokinase (2)

RANKL/RANK (2)

Amylase (2)

Adiponectin Receptor (2)

Monoamine Transporter (2)

Bombesin Receptor (2)

PDGFR (2)

PAK (2)

Aurora Kinase (2)

cAMP (2)

SGLT (2)

ATP Citrate Lyase (2)

Acyltransferase (2)

OAT (2)

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PAI-1 (2)

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Casein Kinase (2)

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IRAK (2)

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Advanced Glycation End Products (1)

Mdm2 (1)

Adenylyl Cyclase (1)

Transaminase (1)

NPC1L1 (1)

Monocarboxylate transporter (1)

stilbene oxidase (1)

Hydrogenase (1)

CYP19A1 (1)

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MyD88 (1)

LPL Receptor (1)

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IFNAR (1)

Aconitase (1)

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Cell wall (1)

Histone Demethylase (1)

PERK (1)

gp120/CD4 (1)

Factor Xa (1)

Melatonin Receptor (1)

c-Myc (1)

CaSR (1)

Glutaminase (1)

IDO (1)

Prolyl Endopeptidase (PREP) (1)

IRE1 (1)

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Bcr-Abl (1)

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Fas/FasL (1)

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MT Receptor (1)

Glucagon Receptor (1)

GlyT (1)

Hexokinase (1)

DPP-4 (1)

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Oxytocin Receptor (1)

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PLK (1)

Complement System (1)

ATTECs (1)

NMU2R (1)

FLT (1)

ROS Kinase (1)

CFTR (1)

PD-1/PD-L1 (1)

PKM (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

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