肠道微生物代谢化合物库

Gut Microbial Metabolite Library

产品编号： L2540

肠道菌群在人体内形成了错综复杂的微生态系统，肠道微生物基因组中富含参与碳水化合物、氨基酸、甲烷、维生素和短链脂肪酸代谢的基因，其中很大一部分是人体自身所不具备的，表明肠道微生物是人体代谢的重要参与者，人体代谢平衡状况与肠道菌群的结构组成变化密不可分。

肠道菌群与人类健康息息相关，肠道菌群异常可能导致多种代谢疾病发生，包括肥胖、2型糖尿病、非酒精性脂肪肝、代谢性心脏病和营养不良等。此外，由于肠道是人体内重要的免疫器官，肠道微生物与宿主在肠道黏膜表面的交流促进了免疫系统的建立和发展，成为人体重要的免疫屏障。肠道菌群代谢产物和衍生物可作为菌群的“信使”，影响宿主能量稳态、机体肥胖、葡萄糖耐量、炎症和内分泌调节等，调控宿主代谢。因此研究肠道微生物代谢产物可能有助于发现某些疾病发病机制及开发有效治疗方法。

TargetMol 肠道微生物代谢化合物库收集了540 种肠道微生物代谢物，可以用于肠道菌群的相关研究及药物开发。

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产品规格

技术资料

陶术生物化合物库目录(2.8MB)

库化合物信息

Excel

SDF

产品描述

540 种肠道微生物代谢物的集合，可以用于高通量和高内涵筛选；
包含脂肪酸、氨基酸、维生素、糖类、脂质等化合物类型；
研究肠道菌群代谢和相关药物开发的有效工具；
详细的说明书，化合物结构、靶点信息、IC50值、活性描述等；
NMR、HPLC/LCMS等多种检测技术保证产品结构正确，纯度高，减少假阳性。

化合物库定制

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化合物库咨询

化合物库组成

Endogenous Metabolite (467)

Apoptosis (25)

Antibacterial (19)

Antioxidant (13)

Autophagy (11)

Amino Acids and Derivatives (8)

DNA/RNA Synthesis (8)

Antifungal (7)

Influenza Virus (7)

GABA Receptor (7)

Ferroptosis (6)

iGluR (6)

Reactive Oxygen Species (6)

Antibiotic (6)

Dehydrogenase (5)

PPAR (5)

Nucleoside Antimetabolite/Analog (5)

Calcium Channel (5)

Virus Protease (4)

NMDAR (4)

5-HT Receptor (4)

Tyrosinase (4)

Chloride channel (3)

Estrogen/progestogen Receptor (3)

Arginase (3)

Adenosine Receptor (3)

Phosphatase (3)

FXR (3)

Caspase (3)

GluR (3)

NF-κB (3)

AMPK (3)

TNF (3)

ATPase (2)

Dopamine Receptor (2)

p38 MAPK (2)

Histamine Receptor (2)

Mitophagy (2)

Vitamin (2)

TRP/TRPV Channel (2)

ERK (2)

Adrenergic Receptor (2)

Aryl Hydrocarbon Receptor (2)

Drug Metabolite (2)

Mitochondrial Metabolism (2)

MMP (2)

COX (2)

Akt (2)

AChE (2)

GPCR19 (2)

Sirtuin (2)

Nrf2 (2)

GPR (2)

Potassium Channel (2)

AhR (2)

NO Synthase (2)

HIV Protease (1)

Carbonic Anhydrase (1)

Transferase (1)

Transaminase (1)

DHFR (1)

ROR (1)

PI3K (1)

P2Y Receptor (1)

Reductase (1)

aconitase (1)

NADPH (1)

Histone Demethylase (1)

JNK (1)

Glutathione Peroxidase (1)

Progesterone Receptor (1)

Melatonin Receptor (1)

c-Myc (1)

HBV (1)

Estrogen Receptor/ERR (1)

Wnt/beta-catenin (1)

Parasite (1)

PARP (1)

Serotonin Transporter (1)

Glucokinase (1)

PKC (1)

MAO (1)

LDL (1)

MT Receptor (1)

Phosphorylase (1)

GlyT (1)

Antifection (1)

ROS (1)

Fatty Acid Synthase (1)

HSV (1)

IL Receptor (1)

CXCR (1)

IGF-1R (1)

CaMK (1)

mTOR (1)

Glutathione reductase (1)

HSP (1)

Prostaglandin Receptor (1)

Trk receptor (1)

Decarboxylase (1)

Reverse Transcriptase (1)

P450 (1)

PLK (1)

FGFR (1)

Cannabinoid Receptor (1)

AChR (1)

Neurokinin receptor (1)

NOD (1)

HIF/HIF Prolyl-Hydroxylase (1)

CFTR (1)

Imidazoline Receptor (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

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