糖酵解化合物库

Glycolysis Compound Library

产品编号： L2521

糖酵解途径又称 EMP 途径(Embden-Meyerhof-Parnas pathway)，指在无氧条件下葡萄糖通过一系列步骤，降解成丙酮酸并生成 ATP 的过程，糖酵解发生在所有活细胞中。研究发现即使在有氧状态下，肿瘤细胞仍会优先选择糖酵解途径提供能量，称为有氧糖酵解（Warburg 效应）。与正常细胞比较，肿瘤细胞会消耗更多的葡萄糖，所以通过定位消耗大量葡萄糖的区域可以帮助识别癌症。因此靶向肿瘤细胞的糖酵解有望成为治疗肿瘤的一个重要治疗策略。

TargetMol 收集了 555 种靶向糖酵解相关的活性化合物，可用于抗肿瘤和糖代谢相关药物开发。

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产品规格

技术资料

陶术生物化合物库目录(2.8MB)

库化合物信息

Excel

SDF

产品描述

555种糖酵解相关的活性化合物，可用于高通量和高内涵筛选；
作用靶点包含己糖激酶（hexokinase）；丙酮酸激（pyruvate kinase）；葡萄糖激酶（glucokinase）等糖酵解关键酶；
详细的说明书，化合物结构、靶点信息、活性描述等；
NMR和HPLC检测技术保证产品高纯度和高质量；
所有化合物现货供应。

化合物库定制

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化合物库组成

PI3K (157)

Autophagy (103)

Apoptosis (103)

Akt (85)

mTOR (84)

AMPK (60)

GSK-3 (52)

HIF/HIF Prolyl-Hydroxylase (40)

DNA-PK (37)

HIF (29)

S6 Kinase (29)

CDK (26)

ATM/ATR (22)

Endogenous Metabolite (21)

Glucokinase (20)

PDK (19)

Antibacterial (18)

c-Myc (16)

NF-κB (16)

ERK (15)

Reactive Oxygen Species (15)

transporter (15)

PI4K (13)

PKC (11)

p38 MAPK (10)

PKA (10)

Parasite (10)

VEGFR (9)

Src (8)

Mitophagy (8)

PKM (8)

HIV Protease (7)

Dehydrogenase (7)

JNK (7)

PTEN (7)

Chk (7)

TNF (7)

PPAR (6)

Caspase (6)

ROCK (6)

MAPK (6)

Casein Kinase (6)

Influenza Virus (6)

STAT (6)

Antibiotic (6)

Phosphatase (5)

SIK (5)

IL Receptor (5)

COX (5)

MELK (5)

MEK (5)

FLT (5)

HSV (4)

MMP (4)

P450 (4)

Potassium Channel (4)

HCV Protease (3)

Virus Protease (3)

Calcium Channel (3)

PDE (3)

Raf (3)

Mitochondrial Metabolism (3)

Hexokinase (3)

JAK (3)

PDGFR (3)

Lipoxygenase (3)

IGF-1R (3)

Interleukin (3)

SGK (3)

Microtubule Associated (3)

Chloride channel (2)

Carbonic Anhydrase (2)

Integrin (2)

Ferroptosis (2)

Adenosine Receptor (2)

Tyrosine Kinases (2)

Wnt/beta-catenin (2)

PARP (2)

Adrenergic Receptor (2)

Bcr-Abl (2)

Glucosidase (2)

BCL (2)

Fatty Acid Synthase (2)

Aurora Kinase (2)

Epigenetic Reader Domain (2)

TGF-beta/Smad (2)

EGFR (2)

SGLT (2)

ATP Citrate Lyase (2)

DNA/RNA Synthesis (2)

Antiviral (2)

Prostaglandin Receptor (2)

Beta Amyloid (2)

HDAC (2)

PLK (2)

c-RET (2)

FGFR (2)

Cannabinoid Receptor (2)

Tyrosinase (2)

ATPase (1)

Proton pump (1)

NOS (1)

NPC1L1 (1)

Estrogen/progestogen Receptor (1)

YAP (1)

Antifungal (1)

c-Met/HGFR (1)

Antioxidant (1)

BACE (1)

IFNAR (1)

DYRK (1)

PERK (1)

RAAS (1)

MRP (1)

HBV (1)

Estrogen Receptor/ERR (1)

Pim (1)

Rho (1)

Hck (1)

Serine Protease (1)

cell cycle arrest (1)

Serine/threonin kinase (1)

FXR (1)

Glutaminase (1)

Aryl Hydrocarbon Receptor (1)

MAO (1)

Topoisomerase (1)

Myosin (1)

E1/E2/E3 Enzyme (1)

Gamma-secretase (1)

Drug Metabolite (1)

Phosphorylase (1)

Guanylate cyclase (1)

CXCR (1)

GluR (1)

CaMK (1)

Androgen Receptor (1)

BCRP (1)

Beta-Secretase (1)

AChE (1)

P-gp (1)

OAT (1)

Trk receptor (1)

Sirtuin (1)

Nrf2 (1)

IκB/IKK (1)

Reverse Transcriptase (1)

c-Fms (1)

KLF (1)

CRISPR/Cas9 (1)

GABA Receptor (1)

AChR (1)

DAPK (1)

c-Kit (1)

cholecystokinin (1)

FAK (1)

CFTR (1)

p53 (1)

PD-1/PD-L1 (1)

Kinesin (1)

NO Synthase (1)

S1P Receptor (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

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