精选先导化合物类似物库

Elite Library

产品编号： AN1100

我们设计的大型筛选库采用了一种新的方法，旨在提供可靠的初步命中源。库中的每个化合物都经过了严格的药物化学过滤、质量控制和物质的可视检查。这个高度复杂的HTS库的构建使您能够在首次筛选后立即获得初步的SAR数据，并帮助您确定安全的hits，您可以比其他任何商业多样性库更安全地跟进。药化学家主要关注点是领先的分子，以便为识别出的命中物的进化提供更多的空间。这些化合物在Elite库中已经进行了一系列早期的ADMET测试（包括DMSO和水溶解度、PAMPA、PGP和CYP抑制），以确保筛选命中物不具有潜在的ADMET问题，并且适合于快速的命中到引领的优化过程。Elite Library提供了独家的预装多样性库，总共包含91,001个新颖的筛选化合物。它们的设计旨在通过提供结构多样性的小分子化合物集合，以方便高通量筛选工作。

陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。

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技术资料

陶术生物化合物库目录(2.8MB)

库化合物信息

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Product Description

A new approach to the design of our largest screening library aims to deliver the most reliable source of initial hits. Each compound in the library passed stringent MedChem filters, QC control, and visual inspection of a substance. The sophisticated construction of this HTS Library allows you to get initial SAR data immediately after a first screen and will help you to determine safe hits, which you can follow more securely than any other from commercial diversity libraries. The main focus at medicinal chemistry hand was fixed on the lead-like molecules to give more space for the evolution of identified hits. These compounds in Elite Library have been screened against a panel of early ADMET tests (including DMSO and water solubility, PAMPA, PGP, and CYP inhibition) to make sure screening hits are devoid of potential ADMET problems and are amenable for rapid hit-to-lead optimization.

化合物库定制

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化合物库组成

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

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