药物代谢杂质库

Drug Metabolite/Impurity Library

产品编号： L5800

随着科研深入，科学家们发现已经上市的药物异构体/代谢产物中很多都是有明确的生物活性的。比如：左丙氧芬(levopropoxyphene)曾是 FDA 批准的镇咳药，而它的旋光异构体右丙氧芬(Dextropropoxyphene)是则有镇痛效果。再比如右旋索它洛尔属于 III 类抗心律失常药，而左旋体则为β-受体阻滞剂。这些化合物在科研上已有的药理评价数据较为丰富，作为老药新用的切入点较为理想。

TargetMol 作为全球知名的化合物库供应商，积极关注科研动态，药物代谢杂质库共有197 种产品，多样性好，重复供应能力强，为您提供药物筛选的一站式服务。

陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。

产品规格

技术资料

陶术生物化合物库目录(2.8MB)

库化合物信息

Excel

SDF

产品描述

197 种药物异构体/代谢产物的特有集合，可用于高通量、高内涵筛选；
可提供基于筛选片段的衍生物以及定制合成服务，降低您的合成成本，缩短研发时间；
结构多样，药效显著，可渗透细胞；
详细的说明书，化合物结构、靶点信息、IC50值、活性描述等；
NMR、HPLC/LCMS等多种检测技术保证产品结构正确，纯度高，减少假阳性。

化合物库定制

我们的化合物库可以灵活定制！了解更多

化合物库咨询

化合物库组成

Endogenous Metabolite (35)

Apoptosis (9)

Autophagy (8)

DNA/RNA Synthesis (6)

Antibiotic (6)

Amino Acids and Derivatives (5)

Antioxidant (4)

Nucleoside Antimetabolite/Analog (4)

Drug Metabolite (4)

COX (4)

Antibacterial (4)

Estrogen/progestogen Receptor (3)

5-HT Receptor (3)

HIV Protease (2)

Adenosine Receptor (2)

Mitophagy (2)

Factor Xa (2)

Estrogen Receptor/ERR (2)

VEGFR (2)

Adrenergic Receptor (2)

ROS (2)

PDGFR (2)

Aromatase (2)

NF-κB (2)

P450 (2)

AChR (2)

c-Kit (2)

Microtubule Associated (2)

Thyroid hormone receptor(THR) (1)

ATPase (1)

Proton pump (1)

CAT (1)

Dopamine Receptor (1)

p38 MAPK (1)

Dehydrogenase (1)

Antifungal (1)

PI3K (1)

DNA Alkylator/Crosslinker (1)

P2Y Receptor (1)

Histamine Receptor (1)

Glutathione Peroxidase (1)

c-Myc (1)

PPAR (1)

Parasite (1)

Glucokinase (1)

Calcium Channel (1)

Aryl Hydrocarbon Receptor (1)

iGluR (1)

Topoisomerase (1)

PDE (1)

Raf (1)

P2X Receptor (1)

NMDAR (1)

DPP-4 (1)

PAK (1)

IL Receptor (1)

CXCR (1)

Xanthine Oxidase (1)

Lipoxygenase (1)

IGF-1R (1)

Norepinephrine (1)

Androgen Receptor (1)

P-gp (1)

Trk receptor (1)

Nrf2 (1)

GABA Receptor (1)

c-RET (1)

Neurokinin receptor (1)

Sodium Channel (1)

S6 Kinase (1)

Tyrosinase (1)

Imidazoline Receptor (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

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