临床期小分子药物库

Clinical Compound Library

产品编号： L3400

临床期小分子药物库汇集了3404 个已经进入临床实验的化合物，这些化合物经过大量的临床前研究实验，具有活性高、毒性低和机制明确的特点。我们随货信息中每个化合物都包含了其作用靶点、临床期、适应症等信息，涉及癌症、炎症、感染、神经病、心血管病和消化系统疾病等多种热门病症，以及JAK、EGFR、mTOR、CDK、HDAC、AKt、PARP 等众多成药靶点，适用于药物筛选的同时，也是细胞诱导分化的有力工具。

陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。

产品规格

技术资料

陶术生物化合物库目录(2.8MB)

库化合物信息

Excel

SDF

产品描述

3404个临床期化合物集合，可用于高通量筛选和高内涵筛选；
所有化合物均已被批准进入临床期，按临床一期、二期、三期等进行分类；
是老药新用和细胞诱导的有效工具
详细的说明书，化合物结构、靶点信息、IC50值、活性描述等；
结构多样，药效显著，可渗透细胞；
NMR、HPLC/LCMS等多种检测技术保证产品结构正确，纯度高，减少假阳性。

化合物库定制

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化合物库组成

Autophagy (370)

Apoptosis (367)

Antibacterial (231)

Antibiotic (220)

Endogenous Metabolite (206)

5-HT Receptor (144)

Adrenergic Receptor (109)

DNA/RNA Synthesis (95)

HIV Protease (92)

AChR (90)

Dopamine Receptor (88)

COX (84)

VEGFR (77)

Histamine Receptor (75)

Parasite (70)

Sodium Channel (69)

Calcium Channel (64)

EGFR (64)

PI3K (63)

Antifungal (62)

Potassium Channel (61)

PDE (58)

FLT (56)

Topoisomerase (55)

HCV Protease (51)

CDK (51)

PDGFR (50)

JAK (50)

P450 (50)

Dehydrogenase (46)

c-Kit (46)

PPAR (44)

Reactive Oxygen Species (44)

FGFR (44)

Microtubule Associated (44)

SARS-CoV (43)

Ferroptosis (42)

HDAC (42)

Glucocorticoid Receptor (41)

mTOR (41)

c-Met/HGFR (39)

Influenza Virus (38)

Estrogen/progestogen Receptor (35)

GABA Receptor (35)

Src (34)

Mitophagy (34)

NF-κB (34)

RAAS (33)

Nucleoside Antimetabolite/Analog (33)

HBV (32)

Prostaglandin Receptor (32)

Reverse Transcriptase (31)

Tyrosine Kinases (29)

GPR (29)

Adenosine Receptor (28)

Bcr-Abl (26)

Raf (26)

Proteasome (25)

BTK (25)

Androgen Receptor (24)

Akt (24)

PARP (23)

Serotonin Transporter (23)

iGluR (23)

ADC Cytotoxin (22)

Aurora Kinase (22)

Epigenetic Reader Domain (22)

HER (22)

Phosphatase (21)

Virus Protease (21)

ROS (21)

HSV (21)

MEK (21)

Transferase (20)

p38 MAPK (20)

Progesterone Receptor (20)

Estrogen Receptor/ERR (20)

GluR (20)

Norepinephrine (20)

TRP/TRPV Channel (19)

IL Receptor (19)

HSP (19)

Beta Amyloid (19)

NMDAR (18)

Opioid Receptor (18)

ALK (18)

c-RET (18)

TNF (18)

HIF/HIF Prolyl-Hydroxylase (18)

ERK (17)

DPP-4 (17)

P-gp (17)

Trk receptor (17)

ATPase (16)

Carbonic Anhydrase (16)

Antioxidant (16)

Antifection (16)

DNA Alkylator/Crosslinker (15)

GSK-3 (15)

PKC (15)

CCR (15)

AChE (15)

Antiviral (15)

c-Fms (15)

ribosome (15)

Thrombin (15)

Proton pump (14)

Gamma-secretase (14)

Mitochondrial Metabolism (14)

CXCR (14)

Endothelin Receptor (14)

Interleukin (14)

TLR (14)

Retinoid Receptor (14)

TAM Receptor (14)

Histone Methyltransferase (13)

DNA-PK (13)

MAO (13)

E1/E2/E3 Enzyme (13)

BCL (13)

Chk (13)

MMP (13)

STAT (13)

AMPK (13)

Phospholipase (13)

S1P Receptor (13)

Thyroid hormone receptor(THR) (12)

LPL Receptor (12)

Caspase (12)

SGLT (12)

HIF (12)

Syk (12)

NO Synthase (12)

Antifolate (11)

Guanylate cyclase (11)

DNA Alkylation (11)

CFTR (11)

p53 (11)

Integrin (10)

NADPH (10)

CSF-1R (10)

Hedgehog/Smoothened (10)

Nrf2 (10)

CETP (9)

Glutathione Peroxidase (9)

MRP (9)

PKA (9)

Wnt/beta-catenin (9)

P2X Receptor (9)

Lipoxygenase (9)

IGF-1R (9)

TGF-beta/Smad (9)

Hydroxylase (9)

PLK (9)

Cannabinoid Receptor (9)

HMG-CoA Reductase (9)

S6 Kinase (9)

FAK (9)

Monoamine Oxidase (9)

Mdm2 (8)

DHFR (8)

P2Y Receptor (8)

Reductase (8)

JNK (8)

ROCK (8)

IAP (8)

Drug Metabolite (8)

Glucosidase (8)

Vasopressin Receptor (8)

Indoleamine 2,3-Dioxygenase (IDO) (8)

Sirtuin (8)

RSV (8)

ATM/ATR (8)

Kras (8)

Neurokinin receptor (8)

ROS Kinase (8)

CAT (7)

Histone Demethylase (7)

GNRH Receptor (7)

Serine Protease (7)

FXR (7)

Aryl Hydrocarbon Receptor (7)

RIP kinase (7)

Smo (7)

OX Receptor (7)

Xanthine Oxidase (7)

DNA (7)

Beta-Secretase (7)

Aminopeptidase (7)

Casein Kinase (7)

DNA Methyltransferase (7)

Sigma receptor (7)

Kinesin (7)

ROR (6)

Amino Acids and Derivatives (6)

BACE (6)

Pim (6)

Leukotriene Receptor (6)

Glucokinase (6)

Glucagon Receptor (6)

Isocitrate Dehydrogenase (IDH) (6)

PAK (6)

Bradykinin Receptor (6)

IκB/IKK (6)

Ligand for E3 Ligase (6)

IRAK (6)

AhR (6)

Tie-2 (5)

Factor Xa (5)

IDO (5)

DNA gyrase (5)

Fatty Acid Synthase (5)

Acyltransferase (5)

Ephrin Receptor (5)

Complement System (5)

Chloride channel (4)

NOS (4)

DprE1 (4)

LTR (4)

IFNAR (4)

Melatonin Receptor (4)

Liver X Receptor (4)

MT Receptor (4)

Monoamine Transporter (4)

Molecular Glues (4)

FAAH (4)

KSP (4)

CaMK (4)

Wee1 (4)

PGE Synthase (4)

Decarboxylase (4)

CRFR (4)

Neprilysin (4)

Acetyl-CoA Carboxylase (4)

GHSR (4)

CGRP Receptor (4)

Gap Junction Protein (4)

NADPH-oxidase (4)

Ras (4)

cholecystokinin (4)

CRM1 (3)

Arginase (3)

YAP (3)

Cell wall (3)

PERK (3)

ABC (3)

CaSR (3)

Rho (3)

Serine/threonin kinase (3)

Cysteine Protease (3)

NAMPT (3)

Myosin (3)

Annexin A (3)

GlyT (3)

Neuropeptide Y Receptor (3)

Somatostatin (3)

DUB (3)

Telomerase (3)

PSMA (3)

OAT (3)

STING (3)

GPCR19 (3)

Free radical scavengers (3)

LPA Receptor (3)

Melanocortin Receptor (3)

PDK (3)

Adenosine deaminase (3)

Tyrosinase (3)

Protease-activated Receptor (3)

NOD-like Receptor (NLR) (3)

Imidazoline Receptor (3)

PD-1/PD-L1 (3)

Taste receptor (2)

PROTACs (2)

NEDD8 (2)

Ligands for Target Protein for PROTAC (2)

VDA (2)

Galectin (2)

PYK2 (2)

Vitamin (2)

IRE1 (2)

UGT (2)

LDL (2)

Na-K-Cl cotransporter (2)

Hexokinase (2)

Integrase (2)

HCN Channel (2)

Stearoyl-CoA Desaturase (SCD) (2)

Epoxide Hydrolase (2)

ATP Citrate Lyase (2)

BCRP (2)

MAPK (2)

Porcupine (2)

CD73 (2)

transporter (2)

PAI-1 (2)

Drug-Linker Conjugates for ADC (2)

GST (2)

Oxytocin Receptor (2)

Discoidin Domain Receptor (DDR) (2)

p97 (2)

MLK (2)

advanced glycation end products (1)

Adenylyl cyclase (1)

GSNOR (1)

NPC1L1 (1)

Monocarboxylate transporter (1)

Hydrogenase (1)

MALT (1)

Arrestin (1)

RAR/RXR (1)

DYRK (1)

Lipase (1)

TOPK (1)

GTPase (1)

c-Myc (1)

N-Acetylglucosaminyltransferase (1)

VDAC (1)

Hck (1)

Stemness kinase (1)

Glutaminase (1)

FLAP (1)

PAFR (1)

MTH1 (1)

Fas/FasL (1)

GRK (1)

Phosphorylase (1)

AAK1 (AP2 associated kinase 1) (1)

Anion Exchanger (1)

PROTAC Linker (1)

Thioredoxin (1)

ACK (1)

Lipid (1)

Survivin (1)

MNK (1)

Histone Acetyltransferase (1)

ASK (1)

GluCls (1)

Pyroptosis (1)

MELK (1)

Methionine Adenosyltransferase (MAT) (1)

Hippo pathway (1)

Aromatase (1)

KLF (1)

PI4K (1)

CRISPR/Cas9 (1)

Aquaporin (1)

SGK (1)

Anti-infection (1)

NOD (1)

BMI-1 (1)

PKM (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

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