癌细胞分化化合物库

Cancer Cell Differentiation Compound Library

产品编号： L2140

癌症已经是全球第二大死亡原因，无论在发达国家还是在发展中国家，死亡率和发病率仍不断增高。在癌症中，分化指肿瘤组织与其来源的正常组织相比，相似程度大小。分化良好的癌细胞看起来更像正常细胞，倾向于比低分化或未分化的癌细胞生长和传播的慢。因此分化可用于肿瘤分级系统。

诱导恶性肿瘤细胞分化成熟是恶性肿瘤防治的主要研究方向之一。细胞分化的关键环节是基因调控，故基因表达时间/空间差异性、差异调控下新合成的特异性蛋白质、不同细胞表面抗原以及异常细胞周期、信号传导通路等成为恶性肿瘤细胞分化机制的主要研究点。除了本库中收录的573 个诱导肿瘤细胞分化的小分子外，您也可以参考我们的抗癌分子库，抗癌上市药物库，抗癌临床药物库等。

陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。

产品规格

技术资料

陶术生物化合物库目录(2.8MB)

库化合物信息

Excel

SDF

产品描述

573个诱导肿瘤细胞分化化合物的独特集合，可用于高通量筛选和高内涵筛选；
提供产品的来源、化学信息和生物学信息，为筛选提供理论方向和研究基础；
结构多样，药效显著，可渗透细胞；
NMR、HPLC/LCMS检测技术保证产品高纯度和高质量，减少假阳性发生概率。

化合物库定制

我们的化合物库可以灵活定制！了解更多

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化合物库组成

Autophagy (97)

Wnt/beta-catenin (91)

Apoptosis (81)

PI3K (60)

Retinoid Receptor (43)

HDAC (35)

Hedgehog/Smoothened (35)

mTOR (35)

p38 MAPK (33)

TGF-beta/Smad (30)

GSK-3 (26)

Akt (20)

STAT (20)

ERK (19)

ALK (16)

DNA-PK (16)

ATM/ATR (14)

CDK (14)

Gamma-secretase (14)

S6 Kinase (13)

PARP (11)

Smo (11)

AMPK (8)

Casein Kinase (7)

Antibiotic (6)

Epigenetic Reader Domain (5)

P450 (5)

PDK (5)

PKA (5)

PKC (5)

Src (5)

Antibacterial (4)

Chk (4)

HIV Protease (4)

MEK (4)

Mitophagy (4)

Raf (4)

Antifungal (3)

Aurora Kinase (3)

Beta Amyloid (3)

COX (3)

FGFR (3)

FLT (3)

JAK (3)

Lipid (3)

MAPK (3)

Parasite (3)

Porcupine (3)

RAR/RXR (3)

ROCK (3)

VEGFR (3)

Carbonic Anhydrase (2)

c-Fms (2)

EGFR (2)

Influenza Virus (2)

IκB/IKK (2)

Phosphatase (2)

PI4K (2)

PPAR (2)

Tyrosine Kinases (2)

Virus Protease (2)

ABC (1)

Acyltransferase (1)

Adenosine Receptor (1)

Adenylyl cyclase (1)

Adrenergic Receptor (1)

Antioxidant (1)

ATPase (1)

Bcr-Abl (1)

Calcium Channel (1)

CCR (1)

c-Kit (1)

c-Met/HGFR (1)

CRISPR/Cas9 (1)

Dehydrogenase (1)

DNA (1)

DNA/RNA Synthesis (1)

Drug Metabolite (1)

Fatty Acid Synthase (1)

HCV Protease (1)

HER (1)

HSV (1)

IGF-1R (1)

IL Receptor (1)

Immunology/Inflammation related (1)

Isocitrate Dehydrogenase (IDH) (1)

JNK (1)

MELK (1)

Methionine Adenosyltransferase (MAT) (1)

MLK (1)

MNK (1)

NF-κB (1)

NO Synthase (1)

NOS (1)

PDGFR (1)

PERK (1)

PLK (1)

Potassium Channel (1)

Prostaglandin Receptor (1)

Ras (1)

RIP kinase (1)

S1P Receptor (1)

Serine Protease (1)

SGK (1)

Tie-2 (1)

TNF (1)

TRP/TRPV Channel (1)

YAP (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

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