抗抑郁症化合物库

Antidepressant Compound Library

产品编号： L9860

抑郁症是一种常见的精神障碍，世界卫生组织（WHO）发布的统计报告显示，世界上有超过3.5亿人受抑郁症困扰，并且还在快速增长中。抑郁症主要表现为注意力不集中、情绪低落、思维迟缓、睡眠紊乱，食欲体重变化等症状，还会产生悲观厌世甚至自杀想法，每年有超过80万人因抑郁症自杀身亡。药物治疗作为抑郁症治疗的主要手段，近几十年来开发了一系列抗抑郁药物，但现有抗抑郁药物有一定的局限性，如临床效应滞后或低反应，以及一系列潜在的副作用，抗抑郁药物的发展和抑郁症的发病相比相对比较缓慢，开发抗抑郁症药物已被WHO 列入21世纪迫切开发的药物 TargetMol 抗抑郁症化合物库收集了1163 种与抑郁症相关的化合物，包括已经报道具有抑郁症治疗作用的化合物，以及靶向抑郁症相关靶点的化合物，是抗抑郁症药物研发的良好工具。

陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。

产品规格

技术资料

陶术生物化合物库目录(2.8MB)

库化合物信息

Excel

SDF

产品描述

1163种与抑郁症相关的化合物，可以用于高通量和高内涵筛选；
部分化合物已上市或已进入临床期；
详细的说明书，化合物结构、靶点信息、活性描述等；
NMR、HPLC/LCMS等多种检测技术保证产品结构正确，纯度高，减少假阳性。

化合物库定制

我们的化合物库可以灵活定制！了解更多

化合物库咨询

化合物库组成

NF-κB (185)

PI3K (168)

Apoptosis (154)

5-HT Receptor (137)

Autophagy (136)

mTOR (88)

Akt (86)

Dopamine Receptor (82)

NMDAR (66)

AMPK (66)

Endogenous Metabolite (60)

GSK-3 (55)

Reactive Oxygen Species (47)

Adrenergic Receptor (40)

iGluR (40)

Antibacterial (38)

Monoamine Oxidase (38)

DNA-PK (37)

Serotonin Transporter (36)

GABA Receptor (36)

ERK (31)

COX (30)

CDK (29)

S6 Kinase (29)

Norepinephrine (28)

MAO (27)

IκB/IKK (27)

p38 MAPK (26)

ATM/ATR (23)

Parasite (21)

GluR (21)

TNF (21)

AChR (21)

Histamine Receptor (19)

JNK (19)

PDK (19)

Mitophagy (15)

Caspase (15)

P450 (15)

STAT (15)

HIV Protease (14)

Potassium Channel (14)

PI4K (13)

Antifungal (12)

Calcium Channel (12)

RIP kinase (12)

IL Receptor (12)

Influenza Virus (12)

Sodium Channel (12)

PKC (11)

Antibiotic (11)

PKA (10)

BCL (10)

NO Synthase (10)

Src (9)

Ferroptosis (9)

Antioxidant (9)

Opioid Receptor (9)

MAPK (9)

MEK (9)

NOD (9)

NOD-like Receptor (NLR) (9)

VEGFR (8)

DNA/RNA Synthesis (8)

Casein Kinase (8)

MMP (7)

Lipoxygenase (7)

Interleukin (7)

PTEN (7)

p53 (7)

NOS (6)

Dehydrogenase (6)

ROCK (6)

PPAR (6)

SIK (6)

Chk (6)

Beta Amyloid (6)

FLT (6)

IRAK (6)

Microtubule Associated (6)

PARP (5)

Topoisomerase (5)

Bcr-Abl (5)

Mitochondrial Metabolism (5)

E1/E2/E3 Enzyme (5)

HSV (5)

Aurora Kinase (5)

JAK (5)

IGF-1R (5)

Antiviral (5)

MELK (5)

HDAC (5)

Chloride channel (4)

Carbonic Anhydrase (4)

Phosphatase (4)

Proteasome (4)

Histone Demethylase (4)

Virus Protease (4)

Wnt/beta-catenin (4)

PDE (4)

Aryl Hydrocarbon Receptor (4)

ROS (4)

Epigenetic Reader Domain (4)

CaMK (4)

TLR (4)

AChE (4)

Nrf2 (4)

FAK (4)

HCV Protease (3)

RAAS (3)

Melatonin Receptor (3)

ATPase (3)

Transferase (3)

Integrin (3)

Amino Acids and Derivatives (3)

TRP/TRPV Channel (3)

Raf (3)

MT Receptor (3)

Glucosidase (3)

TGF-beta/Smad (3)

EGFR (3)

PGE Synthase (3)

P-gp (3)

transporter (3)

PDGFR (3)

Prostaglandin Receptor (3)

FGFR (3)

SGK (3)

HIF (3)

Sigma receptor (3)

Tyrosinase (3)

HIF/HIF Prolyl-Hydroxylase (3)

Estrogen/progestogen Receptor (2)

BACE (2)

Adenosine Receptor (2)

Estrogen Receptor/ERR (2)

Serine Protease (2)

IAP (2)

MRP (2)

Tyrosine Kinases (2)

Rho (2)

Leukotriene Receptor (2)

Gamma-secretase (2)

Drug Metabolite (2)

Guanylate cyclase (2)

Neuropeptide Y Receptor (2)

HSP (2)

SARS-CoV (2)

FAAH (2)

OX Receptor (2)

Androgen Receptor (2)

Trk receptor (2)

GPR (2)

PLK (2)

c-RET (2)

Cannabinoid Receptor (2)

Anti-infection (2)

Imidazoline Receptor (2)

HER (2)

Monocarboxylate transporter (1)

Histone Methyltransferase (1)

c-Met/HGFR (1)

Arrestin (1)

Reductase (1)

DYRK (1)

NADPH (1)

Glutathione Peroxidase (1)

Tie-2 (1)

GTPase (1)

c-Myc (1)

Melanin-concentrating Hormone Receptor (MCHR) (1)

Mdm2 (1)

NPC1L1 (1)

YAP (1)

LTR (1)

IFNAR (1)

PERK (1)

OCT (1)

Serine/threonin kinase (1)

Glucokinase (1)

RANKL/RANK (1)

Glucocorticoid Receptor (1)

Myosin (1)

HBV (1)

Pim (1)

Hck (1)

Liver X Receptor (1)

FXR (1)

Immunology/Inflammation related (1)

GRK (1)

P2X Receptor (1)

GlyT (1)

Antifection (1)

Monoamine Transporter (1)

Fatty Acid Synthase (1)

DNA (1)

DUB (1)

ATP Citrate Lyase (1)

BCRP (1)

Beta-Secretase (1)

STING (1)

LRRK2 (1)

Sirtuin (1)

PAK (1)

Hedgehog/Smoothened (1)

CCR (1)

Indoleamine 2,3-Dioxygenase (IDO) (1)

Telomerase (1)

Aminopeptidase (1)

GST (1)

c-Fms (1)

LPA Receptor (1)

DAPK (1)

HMG-CoA Reductase (1)

cholecystokinin (1)

AhR (1)

MLK (1)

PKM (1)

CRFR (1)

ALK (1)

RSV (1)

Reverse Transcriptase (1)

CRISPR/Cas9 (1)

Phospholipase (1)

Oxytocin Receptor (1)

Adenosine deaminase (1)

Syk (1)

c-Kit (1)

NADPH-oxidase (1)

lysosomal autophagy (1)

Kinesin (1)

S1P Receptor (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

注册成功