抗代谢疾病化合物库

Anti-Metabolism Disease Compound Library

产品编号： L5200

代谢是指一组负责将碳水化合物、脂类和蛋白质转化为能量的生化反应，是维持内环境稳态的一个基本过程。代谢领域研究的重点是调节代谢的基本生物学机制及其在肥胖、糖尿病、心血管疾病和癌症等疾病中的作用。TargetMol 是全球知名的化合物库供应商，积极关注科研动态，为您提供大量代谢疾病研究相关的优质产品，为您的研究或相关药物筛选提供支持。

陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。

产品规格

技术资料

陶术生物化合物库目录(2.8MB)

库化合物信息

Excel

SDF

产品描述

1544个代谢疾病相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
靶点包括CYP、FAAH、IDO、MAO 等代谢相关热门靶点；是研究细胞代谢及相关疾病的有效工具，例如糖尿病、肥胖、高甘油三酯血脂、高胆固醇血症等；
结构多样，药效显著，可渗透细胞；
详细的说明书，化合物结构、靶点信息、IC50值、活性描述等；
NMR、HPLC/LCMS等多种检测技术保证产品结构正确，纯度高，减少假阳性。

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化合物库组成

Autophagy (169)

Apoptosis (122)

P450 (93)

PDE (65)

Dehydrogenase (62)

PPAR (51)

PI3K (46)

AMPK (45)

Antibacterial (41)

Glucocorticoid Receptor (34)

COX (34)

Antibiotic (34)

HSP (30)

mTOR (27)

MAO (26)

Potassium Channel (25)

HIV Protease (24)

Proteasome (23)

FAAH (23)

Carbonic Anhydrase (22)

GSK-3 (22)

Parasite (22)

RAAS (21)

Ferroptosis (20)

Retinoid Receptor (20)

Calcium Channel (19)

Casein Kinase (19)

DPP-4 (18)

Phospholipase (18)

Phosphatase (17)

ROCK (17)

DNA/RNA Synthesis (17)

CDK (16)

Monoamine Oxidase (16)

HIF/HIF Prolyl-Hydroxylase (15)

Transferase (14)

Antifungal (14)

Mitophagy (14)

Reactive Oxygen Species (14)

GPR (14)

NADPH (13)

FXR (13)

Akt (13)

DNA-PK (12)

Mitochondrial Metabolism (12)

SARS-CoV (12)

Histamine Receptor (11)

Adrenergic Receptor (11)

Glucagon Receptor (11)

ATM/ATR (11)

5-HT Receptor (11)

Sodium Channel (11)

Lipase (10)

Glucokinase (10)

Indoleamine 2,3-Dioxygenase (IDO) (10)

Endogenous Metabolite (10)

S6 Kinase (10)

AhR (10)

ROR (9)

HCV Protease (9)

PKA (9)

Lipoxygenase (9)

SGLT (9)

Hydroxylase (9)

HIF (9)

AChR (9)

DHFR (8)

Factor Xa (8)

HBV (8)

Wnt/beta-catenin (8)

Serine Protease (8)

Antifolate (8)

Liver X Receptor (8)

NAMPT (8)

Isocitrate Dehydrogenase (IDH) (8)

Fatty Acid Synthase (8)

Thrombin (8)

Dopamine Receptor (7)

Reductase (7)

Aryl Hydrocarbon Receptor (7)

Stearoyl-CoA Desaturase (SCD) (7)

transporter (7)

PDK (7)

Cannabinoid Receptor (7)

HMG-CoA Reductase (7)

Src (6)

ADC Cytotoxin (6)

Glutathione Peroxidase (6)

PARP (6)

Cysteine Protease (6)

PKC (6)

IDO (6)

ROS (6)

IL Receptor (6)

MMP (6)

Interleukin (6)

Neprilysin (6)

ATPase (5)

Estrogen/progestogen Receptor (5)

CETP (5)

Virus Protease (5)

TRP/TRPV Channel (5)

Xanthine Oxidase (5)

Acyltransferase (5)

Prostaglandin Receptor (5)

Sirtuin (5)

PAI-1 (5)

Reverse Transcriptase (5)

STAT (5)

NF-κB (5)

SGK (5)

TNF (5)

FLT (5)

Tyrosinase (5)

PKM (5)

Chloride channel (4)

p38 MAPK (4)

c-Met/HGFR (4)

Serine/threonin kinase (4)

VEGFR (4)

JAK (4)

HSV (4)

Aurora Kinase (4)

Norepinephrine (4)

DNA (4)

P-gp (4)

Aminopeptidase (4)

Nrf2 (4)

Influenza Virus (4)

IκB/IKK (4)

GABA Receptor (4)

NO Synthase (4)

Thyroid hormone receptor(THR) (3)

NOS (3)

CAT (3)

P2Y Receptor (3)

Adenosine Receptor (3)

Estrogen Receptor/ERR (3)

Caspase (3)

ERK (3)

iGluR (3)

SIK (3)

Annexin A (3)

Phosphorylase (3)

Opioid Receptor (3)

CCR (3)

Vasopressin Receptor (3)

Endothelin Receptor (3)

TGF-beta/Smad (3)

ATP Citrate Lyase (3)

OAT (3)

Decarboxylase (3)

RSV (3)

Acetyl-CoA Carboxylase (3)

Carboxypeptidase (3)

HDAC (3)

ribosome (3)

c-RET (3)

FGFR (3)

NADPH-oxidase (3)

TAM Receptor (3)

Proton pump (2)

NPC1L1 (2)

Histone Methyltransferase (2)

Histone Demethylase (2)

PERK (2)

Progesterone Receptor (2)

ABC (2)

MRP (2)

Rho (2)

Glutaminase (2)

Topoisomerase (2)

E1/E2/E3 Enzyme (2)

UGT (2)

LDL (2)

Drug Metabolite (2)

Glucosidase (2)

Antifection (2)

Hexokinase (2)

BCL (2)

PDGFR (2)

PGC-1α (2)

Chk (2)

OX Receptor (2)

Epoxide Hydrolase (2)

GluR (2)

Epigenetic Reader Domain (2)

IGF-1R (2)

CaMK (2)

Androgen Receptor (2)

Lipid (2)

MAPK (2)

AChE (2)

GPCR19 (2)

ASK (2)

ALK (2)

Beta Amyloid (2)

Adenosine deaminase (2)

MEK (2)

Gap Junction Protein (2)

c-Kit (2)

Ras (2)

Sigma receptor (2)

Microtubule Associated (2)

CFTR (2)

MLK (2)

advanced glycation end products (1)

GSNOR (1)

Monocarboxylate transporter (1)

Integrin (1)

DprE1 (1)

YAP (1)

Antioxidant (1)

LPL Receptor (1)

LTR (1)

IFNAR (1)

RAR/RXR (1)

JNK (1)

Tie-2 (1)

Galectin (1)

CaSR (1)

N-Acetylglucosaminyltransferase (1)

Tyrosine Kinases (1)

Pim (1)

Serotonin Transporter (1)

Nucleoside Antimetabolite/Analog (1)

Leukotriene Receptor (1)

Immunology/Inflammation related (1)

CSF-1R (1)

FLAP (1)

RIP kinase (1)

Adiponectin receptor (1)

Bcr-Abl (1)

FABP (1)

GRK (1)

NMDAR (1)

DNA gyrase (1)

Anion Exchanger (1)

Guanylate cyclase (1)

Smo (1)

PROTAC Linker (1)

MAGL (1)

DNA Alkylation (1)

PAK (1)

Thioredoxin (1)

Hedgehog/Smoothened (1)

CXCR (1)

Telomerase (1)

EGFR (1)

PGE Synthase (1)

Glutathione reductase (1)

Antiviral (1)

TLR (1)

LRRK2 (1)

Trk receptor (1)

Free radical scavengers (1)

GluCls (1)

Pyroptosis (1)

MELK (1)

c-Fms (1)

LPA Receptor (1)

Aromatase (1)

PI4K (1)

CRISPR/Cas9 (1)

Complement System (1)

Platelet aggregation (1)

Syk (1)

BMI-1 (1)

cholecystokinin (1)

ROS Kinase (1)

S1P Receptor (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

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