抗感染化合物库

Anti-Infection Compound Library

产品编号： L1800

当外来生物进入人体并造成伤害时就会发生感染，这些引起感染的外来生物称为病原体，例如细菌、病毒、真菌和寄生虫等。有些感染是轻微的几乎不可察觉，但有些感染严重甚至危及生命，且对治疗有抵抗力。

针对上述情况，TargetMol 精选了3021 种具有抗菌、抗病毒以及抗寄生虫等抗感染活性的化合物的组成抗感染化合物库，以用于抗感染研究中的药物高通量筛选、确认药物靶点以及其他医药研发和科研领域。

陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。

产品规格

技术资料

陶术生物化合物库目录(2.8MB)

库化合物信息

Excel

SDF

产品描述

3021种具有抗感染活性的化合物的特有集合，包括抗细菌、抗真菌、抗巨细胞病毒、抗HIV、抗SARS、抗流感等活性；
含有磺胺类，氨基糖苷类，四环素类和大环内酯类等化合物，是筛选新型抗感染药的有效工具；可用于高通量筛选和高内涵筛选；
通过前期临床研究和临床实验，生物活性和安全性已经得到验证；其中一些抗感染化合物已得到FDA批准上市；
结构多样，药效显著，可渗透细胞；
详细的说明书，化合物结构、靶点信息、IC50值、活性描述等；
NMR、HPLC/LCMS等多种检测技术保证产品结构正确，纯度高，减少假阳性。

化合物库定制

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化合物库组成

Antibacterial (962)

Antibiotic (580)

Antifungal (329)

Parasite (310)

HIV Protease (236)

Autophagy (207)

Apoptosis (207)

Endogenous Metabolite (186)

Influenza Virus (144)

Antiviral (110)

SARS-CoV (108)

DNA/RNA Synthesis (107)

HCV Protease (99)

Virus Protease (83)

HBV (71)

HSV (63)

NF-κB (63)

Anti-infection (63)

Nucleoside Antimetabolite/Analog (54)

COX (51)

Topoisomerase (50)

Reactive Oxygen Species (49)

Antioxidant (48)

Reverse Transcriptase (46)

Antifection (45)

P450 (44)

Dehydrogenase (39)

ribosome (30)

Histamine Receptor (28)

AChR (27)

Mitophagy (24)

Potassium Channel (24)

AChE (23)

GABA Receptor (23)

Calcium Channel (22)

TLR (22)

STAT (22)

Ferroptosis (21)

Phosphatase (21)

IL Receptor (21)

Dopamine Receptor (20)

Adenosine Receptor (20)

JAK (20)

Proton pump (19)

p38 MAPK (19)

PKC (19)

TNF (19)

Sodium Channel (19)

ATPase (18)

TRP/TRPV Channel (18)

RSV (17)

Microtubule Associated (17)

Caspase (16)

ROS (16)

MMP (16)

5-HT Receptor (16)

PI3K (15)

PPAR (15)

Adrenergic Receptor (15)

Akt (15)

HDAC (15)

AMPK (15)

ADC Cytotoxin (14)

PDE (14)

Tyrosinase (14)

Drug Metabolite (13)

DNA gyrase (13)

CCR (13)

Phospholipase (13)

Estrogen/progestogen Receptor (12)

PARP (12)

ERK (12)

CXCR (12)

HSP (12)

Glucocorticoid Receptor (11)

Mitochondrial Metabolism (11)

BCL (11)

EGFR (11)

Cysteine Protease (10)

CDK (10)

Lipoxygenase (10)

Nrf2 (10)

NO Synthase (10)

NOS (9)

DHFR (9)

Wnt/beta-catenin (9)

MAO (9)

mTOR (9)

P-gp (9)

HIF/HIF Prolyl-Hydroxylase (9)

Transferase (8)

JNK (8)

PKA (8)

Estrogen Receptor/ERR (8)

Glucosidase (8)

Epigenetic Reader Domain (8)

DNA Methyltransferase (8)

CAT (7)

Histone Methyltransferase (7)

Serine Protease (7)

VEGFR (7)

NMDAR (7)

Fatty Acid Synthase (7)

Interleukin (7)

PI4K (7)

Proteasome (6)

Chloride channel (6)

Carbonic Anhydrase (6)

Histone Demethylase (6)

Antifolate (6)

Serine/threonin kinase (6)

Immunology/Inflammation related (6)

Gamma-secretase (6)

CaMK (6)

TGF-beta/Smad (6)

STING (6)

Beta Amyloid (6)

Retinoid Receptor (6)

HMG-CoA Reductase (6)

S1P Receptor (6)

Monoamine Oxidase (6)

Src (5)

DprE1 (5)

IFNAR (5)

Cell wall (5)

NADPH (5)

ABC (5)

Tyrosine Kinases (5)

Bcr-Abl (5)

PDGFR (5)

DNA (5)

Sirtuin (5)

IκB/IKK (5)

NADPH-oxidase (5)

Reductase (4)

PERK (4)

GSK-3 (4)

Glucokinase (4)

P2X Receptor (4)

Monoamine Transporter (4)

Opioid Receptor (4)

Xanthine Oxidase (4)

Aurora Kinase (4)

cAMP (4)

DUB (4)

Telomerase (4)

Lipid (4)

MAPK (4)

Aminopeptidase (4)

transporter (4)

ATM/ATR (4)

GPR (4)

HIF (4)

Adenosine deaminase (4)

MEK (4)

Cannabinoid Receptor (4)

NOD (4)

p97 (4)

p53 (4)

Arginase (3)

P2Y Receptor (3)

gp120/CD4 (3)

MRP (3)

Serotonin Transporter (3)

Amylase (3)

iGluR (3)

RIP kinase (3)

Hedgehog/Smoothened (3)

FAAH (3)

Chk (3)

Transketolase (3)

Norepinephrine (3)

Androgen Receptor (3)

Indoleamine 2,3-Dioxygenase (IDO) (3)

BCRP (3)

Acyltransferase (3)

Prostaglandin Receptor (3)

Free radical scavengers (3)

Platelet aggregation (3)

Syk (3)

FLT (3)

S6 Kinase (3)

Ras (3)

Thrombin (3)

FAK (3)

AhR (3)

Thyroid hormone receptor(THR) (2)

DNA-PK (2)

Integrin (2)

Dynamin (2)

CRM1 (2)

c-Met/HGFR (2)

LPL Receptor (2)

LTR (2)

BACE (2)

RAAS (2)

Glutathione Peroxidase (2)

Progesterone Receptor (2)

Liver X Receptor (2)

Leukotriene Receptor (2)

IAP (2)

Annexin A (2)

UGT (2)

Raf (2)

BTK (2)

Guanylate cyclase (2)

Integrase (2)

DNA Alkylation (2)

PAK (2)

Stearoyl-CoA Desaturase (SCD) (2)

PTEN (2)

Epoxide Hydrolase (2)

GluR (2)

PGE Synthase (2)

Histone Acetyltransferase (2)

GluCls (2)

Pyroptosis (2)

Casein Kinase (2)

GST (2)

Acetyl-CoA Carboxylase (2)

CRISPR/Cas9 (2)

PLK (2)

Complement System (2)

c-Kit (2)

NOD-like Receptor (NLR) (2)

PD-1/PD-L1 (2)

PKM (2)

Apelin receptor (1)

advanced glycation end products (1)

Mdm2 (1)

Monocarboxylate transporter (1)

Hydrogenase (1)

EBI2/GPR183 (1)

Amino Acids and Derivatives (1)

YAP (1)

DNA Alkylator/Crosslinker (1)

Lipase (1)

TOPK (1)

VDA (1)

Factor Xa (1)

OCT (1)

c-Myc (1)

GNRH Receptor (1)

Rho (1)

Hck (1)

FXR (1)

LIM Kinase (1)

Glutaminase (1)

ROCK (1)

Aryl Hydrocarbon Receptor (1)

IRE1 (1)

Myosin (1)

E1/E2/E3 Enzyme (1)

Adiponectin receptor (1)

PAFR (1)

MTH1 (1)

Na-K-Cl cotransporter (1)

Hexokinase (1)

MAGL (1)

Bombesin Receptor (1)

Endothelin Receptor (1)

Somatostatin (1)

SGLT (1)

ATP Citrate Lyase (1)

Beta-Secretase (1)

Glutathione reductase (1)

MNK (1)

Trk receptor (1)

Decarboxylase (1)

GPX (1)

Aromatase (1)

Hydroxylase (1)

FGFR (1)

CGRP Receptor (1)

SGK (1)

ATTECs (1)

Gap Junction Protein (1)

Neurokinin receptor (1)

BMI-1 (1)

IRAK (1)

Sigma receptor (1)

TAM Receptor (1)

HER (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

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