抗感染天然产物库

Anti-infective Natural Product Library

产品编号： L6610

当病原体侵入生物组织后，就会引发机体的感染。感染可由多种病原体引起，主要包含细菌，真菌，病毒，寄生虫等。感染性疾病在2013年导致全球920万人死亡，同时，新型传染病和耐药菌 (如冠状病毒变种、MRSA 等) 的出现对全球公共卫生产生了复杂而严峻的挑战。

越来越多的研究表明，天然产物在抗感染方面发挥着独特的作用。天然产物不仅可作用于多种靶点，并且和现有的抗感染药物联合给药时，可以发挥协同作用，不易产生耐药性。

TargetMol 抗感染天然产物库，收集1074 个化合物，具有抗细菌，抗病毒，抗真菌，抗寄生虫及协同抗感染作用的天然产物，可用于高通量筛选和高内涵筛选，是抗感染药物研发领域的有效工具。

陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。

产品规格

技术资料

陶术生物化合物库目录(2.8MB)

库化合物信息

Excel

SDF

产品描述

1074种具有抗感染活性的天然产物特有集合，具有抗细菌、抗真菌、抗HIV、抗SARS、抗流感等活性；
结构多样，包含萜类、生物碱、β-内酰胺类、大环内酯类、氨基糖苷类等类别；
详细的说明书，化合物结构、靶点信息、IC50值、活性描述等；
NMR、HPLC/LCMS等多种检测技术保证产品结构正确，纯度高，减少假阳性。

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化合物库组成

Antibacterial (353)

Endogenous Metabolite (188)

Antibiotic (152)

Antifungal (145)

Apoptosis (134)

Autophagy (97)

Parasite (96)

Influenza Virus (70)

HIV Protease (60)

NF-κB (56)

Anti-infection (52)

Reactive Oxygen Species (42)

Antioxidant (38)

Virus Protease (37)

Antifection (36)

COX (36)

DNA/RNA Synthesis (34)

HSV (26)

Antiviral (24)

P450 (21)

p38 MAPK (20)

IL Receptor (20)

HBV (19)

AChE (18)

TNF (17)

Topoisomerase (16)

Caspase (15)

SARS-CoV (15)

STAT (15)

ribosome (15)

GABA Receptor (15)

Ferroptosis (14)

ROS (14)

HCV Protease (13)

Mitophagy (13)

PPAR (13)

MMP (13)

Dehydrogenase (12)

Calcium Channel (12)

ERK (12)

Akt (12)

Nucleoside Antimetabolite/Analog (11)

AMPK (11)

AChR (11)

Tyrosinase (11)

NO Synthase (11)

JNK (10)

PKC (10)

BCL (10)

ATPase (9)

PARP (9)

Nrf2 (9)

Potassium Channel (9)

PI3K (8)

Immunology/Inflammation related (8)

HDAC (8)

NOS (7)

Estrogen/progestogen Receptor (7)

Phosphatase (7)

Mitochondrial Metabolism (7)

Lipoxygenase (7)

Sodium Channel (7)

ADC Cytotoxin (6)

Wnt/beta-catenin (6)

MAO (6)

Glucosidase (6)

HSP (6)

TLR (6)

Reverse Transcriptase (6)

Phospholipase (6)

Microtubule Associated (6)

Reductase (5)

Estrogen Receptor/ERR (5)

TRP/TRPV Channel (5)

Gamma-secretase (5)

JAK (5)

mTOR (5)

Interleukin (5)

TGF-beta/Smad (5)

Lipid (5)

IκB/IKK (5)

Beta Amyloid (5)

5-HT Receptor (5)

Adenosine Receptor (4)

Histamine Receptor (4)

VEGFR (4)

CCR (4)

EGFR (4)

P-gp (4)

HIF/HIF Prolyl-Hydroxylase (4)

p53 (4)

CAT (3)

Dopamine Receptor (3)

Arginase (3)

BACE (3)

NADPH (3)

ABC (3)

PKA (3)

Tyrosine Kinases (3)

Adrenergic Receptor (3)

Amylase (3)

PDE (3)

NMDAR (3)

Fatty Acid Synthase (3)

Prostaglandin Receptor (3)

Aminopeptidase (3)

transporter (3)

Platelet aggregation (3)

DNA Methyltransferase (3)

HMG-CoA Reductase (3)

FAK (3)

Proteasome (2)

Chloride channel (2)

Proton pump (2)

Carbonic Anhydrase (2)

Transferase (2)

Src (2)

Integrin (2)

P2Y Receptor (2)

MRP (2)

Liver X Receptor (2)

iGluR (2)

PAFR (2)

CDK (2)

DNA gyrase (2)

Monoamine Transporter (2)

Opioid Receptor (2)

PTEN (2)

Xanthine Oxidase (2)

GluR (2)

cAMP (2)

Epigenetic Reader Domain (2)

CaMK (2)

Indoleamine 2,3-Dioxygenase (IDO) (2)

Acyltransferase (2)

Free radical scavengers (2)

Sirtuin (2)

Histone Acetyltransferase (2)

RSV (2)

GST (2)

Retinoid Receptor (2)

GPR (2)

MEK (2)

NOD (2)

NADPH-oxidase (2)

IRAK (2)

S6 Kinase (2)

Monoamine Oxidase (2)

Thyroid hormone receptor(THR) (1)

advanced glycation end products (1)

Mdm2 (1)

Hydrogenase (1)

DHFR (1)

ROR (1)

CYP19A1 (1)

Histone Methyltransferase (1)

Amino Acids and Derivatives (1)

c-Met/HGFR (1)

LTR (1)

Cell wall (1)

Histone Demethylase (1)

gp120/CD4 (1)

Factor Xa (1)

GSK-3 (1)

OCT (1)

c-Myc (1)

Serotonin Transporter (1)

cell cycle arrest (1)

Cysteine Protease (1)

FXR (1)

Glutaminase (1)

Aryl Hydrocarbon Receptor (1)

IAP (1)

Glucocorticoid Receptor (1)

IRE1 (1)

Adiponectin receptor (1)

UGT (1)

MTH1 (1)

Drug Metabolite (1)

P2X Receptor (1)

Hexokinase (1)

Bombesin Receptor (1)

PDGFR (1)

FAAH (1)

Stearoyl-CoA Desaturase (SCD) (1)

CXCR (1)

Somatostatin (1)

Epoxide Hydrolase (1)

Aurora Kinase (1)

IGF-1R (1)

SGLT (1)

ATP Citrate Lyase (1)

BCRP (1)

Beta-Secretase (1)

MAPK (1)

GPCR19 (1)

GluCls (1)

Pyroptosis (1)

Casein Kinase (1)

ATM/ATR (1)

Aromatase (1)

CRISPR/Cas9 (1)

HIF (1)

FGFR (1)

Complement System (1)

ATTECs (1)

FLT (1)

Syk (1)

AhR (1)

HER (1)

PKM (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

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