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血管内皮生长因子受体

血管内皮生长因子受体 (Vascular Endothelial Growth Factor Receptors, VEGFRs) 是血管内皮生长因子(Vascular Endothelial Growth Factor ,VEGF)的受体。VEGFR有三种主要亚型,编号为1、2和3。根据选择性剪接,它们可能是膜结合的 (mbVEGFR) 或可溶的 (sVEGFR)。 VEGFR的细胞外部分由 7 个免疫球蛋白样结构域、一个跨膜区域和一个包含分裂酪氨酸激酶结构域的细胞内部分组成。VEGFR-2 似乎介导了几乎所有已知的细胞对 VEGF 的反应。VEGFR-1 的功能尚不明确,尽管它被认为可以调节 VEGFR-2 信号传导。VEGFR-1 的另一个功能是充当虚拟/诱饵受体,将 VEGF 从 VEGFR-2 结合中隔离出来。VEGFR-1 (sFlt1) 的可变剪接形式不是膜结合蛋白,而是分泌的,主要用作诱饵。VEGFR-3 介导淋巴管生成以响应 VEGF-C 和 VEGF-D。VEGFR抑制剂用于治疗癌症。

目录号 产品名/同用名 种属 表达系统
TMPJ-00414 VEGFR2/KDR Protein, Human, Recombinant (aa 20-764, His & Avi), Biotinylated Human HEK293 Cells
TMPJ-00593 VEGFR2/KDR Protein, Human, Recombinant (aa 20-764, His) Human HEK293 Cells
TMPK-00445 VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
TMPK-00446 VEGFR3/FLT4 Protein, Human, Recombinant (aa 25-776, His & Avi), Biotinylated Human HEK293 Cells
TMPK-00450 VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
TMPK-00451 VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
TMPK-00454 VEGFR2/KDR Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
TMPK-00645 VEGFR2/KDR Protein, Rhesus macaque, Recombinant (His) Rhesus HEK293 Cells
TMPY-00119 FLT1 Protein, Human, Recombinant (hFc) Human HEK293 Cells
TMPY-01044 VEGFR2/KDR Protein, Human, Recombinant (hFc) Human HEK293 Cells
TMPY-01069 VEGFR3/FLT4 Protein, Human, Recombinant (hFc) Human HEK293 Cells
TMPY-01937 VEGFR3/FLT4 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
TMPY-02108 FLT1 Protein, Human, Recombinant (aa 1-756, His) Human HEK293 Cells
TMPY-02678 VEGFR2/KDR Protein, Rat, Recombinant (His) Rat HEK293 Cells
TMPY-02736 VEGFR2/KDR Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
TMPY-02858 VEGFR2/KDR Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
TMPY-03202 VEGFR2/KDR Protein, Rat, Recombinant (hFc) Rat HEK293 Cells
TMPY-03299 FLT1 Protein, Rat, Recombinant (His) Rat HEK293 Cells
TMPY-04530 VEGFR2/KDR Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
TMPY-04794 VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, hFc) Human HEK293 Cells
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