Insulin-like 生长因子家族

胰岛素样生长因子 (Insulin-like Growth Factors, IGFs) 是与胰岛素序列相似度高的蛋白质。IGFs是细胞用来与其生理环境进行交流的复杂系统的一部分。这个复杂的系统通常称为 IGF“轴”，由两个细胞表面受体（IGF1R 和 IGF2R）、两个配体（IGF-1 和 IGF-2）、七个高亲和力 IGF 结合蛋白（IGFBP1~IGFBP7）以及相关的 IGFBP 降解酶（统称为蛋白酶）组成。IGF“轴”也称为生长激素/IGF-1 轴。胰岛素样生长因子 1（IGF-1）主要由肝脏分泌，这是生长激素刺激的结果。其中IGF-1 对于正常生理学的调节以及包括癌症在内的许多病理状态的调节都很重要。IGF“轴”已被证明在促进细胞增殖和抑制细胞死亡中发挥作用。

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目录号	产品名/同用名	种属	表达系统
TMPJ-00164	IGFBP-5 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
TMPJ-00345	IGF2BP-2 Protein, Human, Recombinant (His)	Human	E. coli
TMPJ-00811	IGFBP-1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
TMPJ-01082	IGFBP-5 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
TMPJ-01161	CTGF/CCN2 Protein, Human, Recombinant	Human	HEK293 Cells
TMPJ-01162	CTGF/CCN2 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
TMPJ-01163	CTGF/CCN2 Protein, Human, Recombinant (HEK293, His)	Human	HEK293 Cells
TMPJ-01166	IGFBP-7 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
TMPK-00061	IGF2/IGF-II Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
TMPK-00083	IGF1/IGF-I Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
TMPK-00549	IGFBP-2 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
TMPK-00672	CTGF/CCN2 Protein, Rhesus macaque, Recombinant (His)	Rhesus	HEK293 Cells
TMPK-00838	IGFBP-2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
TMPK-01000	CTGF/CCN2 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
TMPK-01027	IGFBP-7 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
TMPK-01371	IGFBP-7 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
TMPY-00080	IGFBP-1 Protein, Canine, Recombinant (His)	Canine	HEK293 Cells
TMPY-00150	IGF2/IGF-II Protein, Human, Recombinant	Human	P. pastoris (Yeast)
TMPY-00339	IGFL2 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
TMPY-00508	IGFBP-5 Protein, Canine, Recombinant (hFc)	Canine	HEK293 Cells