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纤维生长因子受体

纤维生长因子受体 (Fibroblast Growth Factor Receptors, FGFRs) 是与纤维生长因子 (Fibroblast Growth Factor ,FGF) 蛋白家族成员结合的受体。FGFR 由一个由三个免疫球蛋白样结构域组成的细胞外配体结构域、一个跨膜螺旋结构域和一个具有酪氨酸激酶活性的细胞内结构域组成。FGF/FGFR信号通路与多种癌症有关。目前有作用于所有 FGFR1-4 和其他蛋白质的非选择性 FGFR 抑制剂,以及作用于部分/全部 FGFR1-4 的一些选择性 FGFR 抑制剂,例如AZD4547、BGJ398、JNJ42756493和PD173074。

目录号 产品名/同用名 种属 表达系统
TMPJ-00388 FGFR2IIIc Protein, Human, Recombinant (hFc) Human HEK293 Cells
TMPJ-00389 FGFR2 alpha (IIIc) Protein, Human, Recombinant (hFc) Human HEK293 Cells
TMPJ-00390 FGFR2IIIb Protein, Human, Recombinant (hFc) Human HEK293 Cells
TMPJ-00391 FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc) Human HEK293 Cells
TMPJ-01224 FGFRL1 Protein, Human, Recombinant (His) Human HEK293 Cells
TMPK-00378 FGFR4 beta Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
TMPK-00379 FGFR4 Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
TMPK-00380 FGFR4 beta Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
TMPK-00381 FGFR4 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
TMPK-00384 FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
TMPK-00385 FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
TMPK-00386 FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
TMPK-00387 FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
TMPK-00388 FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
TMPK-00389 FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
TMPK-00390 FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
TMPK-00391 FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
TMPK-00392 FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
TMPK-00393 FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
TMPK-00394 FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
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