TN2964
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3'-Methylflavokawin
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3'-Methylflavokawin shows cytotoxicity against HeLa cells, the IC 50 value comparable to xanthohumol (8.2-19.2 microM).
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TN3170
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6-Geranylnaringenin
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6-Geranylnaringenin is a natural product from Humulus lupulus.
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TN3135
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5-O-Methylnaringenin
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5-O-Methylnaringenin is a marker, reduced MS detection of 5-O-methylnaringenin indicated that nifedipine may preferably remove a proton from the 5-position OH group in the A ring of the flavonoid skeleton.
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TN1573
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Desmethylxanthohumol
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Desmethylxanthohumol shows estrogenic activity.
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TN2314
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Xanthohumol D
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Xanthohumol and xanthohumol D are potent inducers of quinone reductase, suggests that they could be used as chemoprevention agents.
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TN5263
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1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one
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1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one (Xanthohumol) 是一种从蛇麻草中提纯的具有多种生物功能的天然产物。黄腐酚对 HIV-1 有效,可能是一种有趣的先导化合物。它可能代表一种用于 HIV-1 感染的新型化疗药物。
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TN1146
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8-Prenylnaringenin
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8-prenylnaringenin 是一种从啤酒花穗中分离到的异戊烯类黄酮,具有细胞毒性。它能通过激活小鼠 Akt 磷酸化途径,使其从静止诱导的停用性肌肉萎缩中恢复。它能通过诱导内源性和外源性通路介导的凋亡,对 HCT-116 结肠癌细胞产生抗增殖活性。
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TN1325
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(2S)-6-Prenylnaringenin
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(2S)-6-Prenylnaringenin (6-Prenylnaringenin) 是强效植物雌激素 8-prenylnaringenin 的异构体,是前脑中最有效的化合物,在 α+β 结合位点上起GABAA 正变构调节剂的作用。
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T3342
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Xanthohumol
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Xanthohumol 是从啤酒花中分离到的黄酮类化合物,可抑制 COX-1 和 COX-2 活性,具有抗肿瘤,抗血管生成的作用,还具有抗多种病毒的活性。
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TN1373
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α-Humulene
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α-Humulene (Alpha-caryophyllene) 是 Tanacetum vulgareL. 精油的主要成分,显示出抗炎作用,IC50=15±2 μg/mL。它抑制 iNOS 和COX-2表达。
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TN6912
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1-Nonanol
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1-Nonanol (Nonan-1-ol) 是一种香料,具有抗真菌活性,通过破坏细胞膜的完整性和线粒体功能发挥作用。
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