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转化生长因子-β 家族

转化生长因子-β (Transforming Growth Factor-β, TGF-β) 是一种多功能细胞因子,属于转化生长因子超家族,包括三种不同的哺乳动物亚型(TGF-β 1~3,HGNC编号TGFB1、TGFB2、TGFB3)和许多其他信号蛋白。TGFB 蛋白由所有白细胞谱系产生。活化的 TGF-β 复合物与其他因子形成与 TGF-β 受体结合的丝氨酸/苏氨酸激酶复合物。TGF-β受体由1型和2型受体亚基组成。TGF-β结合后,2型受体激酶磷酸化并激活1型受体激酶,从而激活信号级联反应。TGF-β在干细胞分化以及T细胞调控和分化中也起着至关重要的作用。由于其在免疫和干细胞调控和分化中的作用,它是癌症、自身免疫性疾病和传染病领域中研究最多的细胞因子。

目录号 产品名/同用名 种属 表达系统
TMPY-00413 Latent TGF beta 2 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
TMPY-00990 Lefty-A Protein, Human, Recombinant (hFc) Human HEK293 Cells
TMPY-01190 INHBB Protein, Human, Recombinant (His) Human HEK293 Cells
TMPY-01576 Artemin Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
TMPY-01817 GDF-10 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
TMPY-01846 Activin A Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
TMPY-02911 GDNF Protein, Rat, Recombinant (His) Rat Baculovirus Insect Cells
TMPY-03291 SMAD2 Protein, Mouse, Recombinant (His & GST) Mouse Baculovirus Insect Cells
TMPY-03292 SMAD5 Protein, Mouse, Recombinant (His & GST) Mouse Baculovirus Insect Cells
TMPY-03419 SMAD3 Protein, Human, Mouse, Rat, Recombinant (His & GST) Human,Mouse,Rat Baculovirus Insect Cells
TMPY-03469 SMAD5 Protein, Mouse, Recombinant Mouse Baculovirus Insect Cells
TMPY-04534 GDF-8 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
TMPY-04535 GDNF Protein, Canine, Recombinant (hFc) Canine HEK293 Cells
TMPY-04577 TGF beta 2 Protein, Rhesus, Recombinant (His) Rhesus HEK293 Cells
TMPY-05029 INHBE Protein, Human, Recombinant (hFc) Human HEK293 Cells
TMPY-05313 Latent TGF beta 1 Protein, Mouse, Recombinant (His), Biotinylated Mouse HEK293 Cells
TMPY-05314 TGF beta 2 Protein, Mouse, Recombinant (His), Biotinylated Mouse HEK293 Cells
TMPY-05521 Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated Human HEK293 Cells
TMPY-06355 Latent TGF beta 1 & GARP Heterotrimer Protein, Human, Recombinant (His) Human HEK293 Cells
TMPY-06970 GDNF Protein, Human, Recombinant Human E. coli
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