T7732
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Carbenoxolone
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Carbenoxolone (Carbenoxolona) 是 11β-HSD 和 gap junction connexin 通道的抑制剂。 Carbenoxolone 抑制巨噬细胞迁移到心房并防止脂肪肝的发展。
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TP1007
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β-Amyloid (1-42), human
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β-Amyloid (1-42), human 是一种由 42 个氨基酸组成的肽,在阿尔茨海默病的发病机制中起关键作用。
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TN6717
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chaetoglobosin Vb
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chaetoglobosin Vb 是一种从内生球藻中分离出来的新型细胞松弛素生物碱。
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TQ0298
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Fagomine
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Fagomine (D-Fagomine) 是一种温和的糖苷酶 (glycosidase) 抑制剂,是1-脱氧野尻霉素 (DNJ) 的类似物,具有降血糖活性,Fagomine 降低了细胞内活性氧(ROS)的产生和丙二醛(MDA)水平。
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T13670L
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(Z)-Ligustilide
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(Z)-Ligustilide (Ligustilide A) 是从川芎中提取的天然产物,具有抗菌和抗真菌活性。它抑制 FATP5 和 DGAT 的表达,抑制小鼠脂肪酸的摄取和酯化,有潜力研究非酒精性脂肪性肝病。
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T5766
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(+)-Coclaurine
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(+)-Coclaurine 是从多种植物来源中分离出来的四氢异喹啉生物碱,具有抗衰老作用。
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TN3214
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(2S)-7,4'-Dihydroxy-3'-prenylflavan
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7,4'-Dihydroxy-3'-prenylflavan has antibacterial activity.
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T4240
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3',4',7-Trimethoxyflavan
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3',4',7-Trimethoxyflavan 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 T4240,CAS号为 116384-26-0。
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TN5461
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Demethylvestitol
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Demethylvestitol is a natural product from Spatholobus suberectus.
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TN4642
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Neorauflavane
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Neorauflavane shows tyrosinase inhibition, it can inhibit tyrosinase monophenolase activity with an IC50 of 30 nM, it also can efficiently reduce melanin content in B16 melanoma cells with 12.95 uM of IC50.
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TN4383
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Kazinol U
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Kazinol U may have therapeutic value in delaying pancreatic β-cell destruction in type 1 diabetes by blocking the NF-κB pathway in pancreatic β-cells reduces cell damage. Kazinol U shows estrogenic activity with ligand-activity of estrogen receptor, transcriptional activity of estrogen -responsive element-reporter genes, it may have beneficial effects in the treatment of menopausal symptoms.
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TN4327
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Isosativan
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Isosativan, sativan and vestitol are isoflavan phytoalexins.
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TN3215
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7,4'-Dihydroxy-8-methylflavan
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7,4'-Dihydroxy-8-methylflavan can significantly promote mesenchymal stem cells (MSCs) osteogenic differentiation by increasing the levels of alkaline phosphatase (ALP) activity. 7,4'-Dihydroxy-8-methylflavan also has free radical scavenging properties.
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TN5228
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Vestitol
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Vestitol is a phytoalexin with insect feeding-deterrent activity, it has antioxidant, anti-inflammatory and antimicrobial activities, it can inhibit neutrophil migration at a dose of 10 mg/kg, and shows MICs ranging from 25-50 to 50-100 ug/mL and MBCs ranging from 25-50 to 50-100 ug/mL.Vestitol exerts a limited inhibitory effect on S. hermonthica germination, it can significantly inhibit seedling growth, it also contributes, at least in part, to the host's defence mechanism and acts as a chemical barrier against the intrusion of the parasite.
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T7711
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Uridine triphosphate
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Uridine triphosphate (Uridine 5'-triphosphate) 是一种核苷酸,调节胰腺内分泌和外分泌、增殖、通道、转运体和细胞内信号传导的功能。
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TN2180
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Sappanchalcone
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Sappanchalcone shows xanthine oxidase inhibitory activity, is a xanthine oxidase inhibitor.
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TN4580
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Morachalcone A
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Morachalcone A displays significant tyrosinase inhibitory activity (IC50, 0.013 uM); it also exerts strong pancreatic lipase inhibition with IC 50 value of 6.2 uM. Morachalcone A exhibits neuroprotective effects on HT22-immortalized hippocampal cells agai
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TN3063
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4-O-Methylsappanol
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4-O-Methylsappanol shows activity against this fungus against Beauveria bassiana.
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T19461
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N1,N8-Diacetylspermidine
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N1,N8-Diacetylspermidine 是人尿中的一种多胺。N1,N8-Diacetylspermidine 可用作癌症和恶性肿瘤的标记物。
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TN3910
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Ecdysone
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Ecdysone 是存在于昆虫和草药中的主要类固醇激素,可以激活盐皮质激素受体并诱导细胞凋亡。Ecdysone 的活性代谢物 20-羟基蜕皮激素在协调发育过渡和体内稳态睡眠调节中起重要作用。
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