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多肽

多肽是介于大分子蛋白质和小分子药物之间的具有调节细胞生物功能的化合物。由于其主要来源于天然多肽或者天然多肽类似物,通常情况下,其结构清楚、作用机制明确。研究表明多肽具有靶点亲和力高、疗效稳定、免疫原性低、毒副作用小、特异性强等优点。

随着生物技术与多肽合成技术的日臻成熟,越来越多的多肽药物被开发并应用于临床。因适应症广、安全性高且疗效显著,多肽药物目前已被广泛应用于肿瘤、肝炎、糖尿病、艾滋病等领域,具有广阔的开发前景。

TargetMol可为您提供 2000 多种多肽产品供科研工作者研究使用。TargetMol始终致力于服务“科研人员”,将热门的研究报道和产品推送给各位科研人员。

产品编号 产品名称
TP1487 Glucagon-Like Peptide (GLP) II, human Glucagon-like peptide 2 (GLP-2) is a recently identified intestinal epithelium-specific growth factor that has been shown to reduce the severity of inflammatory disorders of the intestine in rodent models. Currently Glucagon-Like Peptide 2 is used as a po
T7601L Carbetocin acetate Carbetocin acetate 是催产素类似物,是催产素受体激动剂,Ki是 7.1 nM。它对催产素受体的嵌合 N 末端具有高亲和力,Ki为 1.17 μM。它能透过血脑屏障,可以通过激活 CNS 中的催产素受体而具有类抗抑郁活性,具有用于产后出血的研究潜力。
TP1382 HAEGTFTSDVS HAEGTFTSDVS is the first N-terminal 1-11 residues of GLP-1 peptide.
TP2312 MOTS-c(Human) Acetate(1627580-64-6 free) MOTS-c(Human) Acetate is a mitochondrial-derived peptide. MOTS-c(human) acetate induces the accumulation of AMP analog AICAR, increases activation of AMPK and expression of its downstream GLUT4. MOTS-c(human) acetate induces glucose uptake and improves in
T7631 Eledoisin Related Peptide Eledoisin Related Peptide 是一种速激肽受体配体,是物质P的类似物,刺激神经元并触发行为反应。
TP1388 HAEGTFTSDVSSYLE HAEGTFTSDVSSYLE 是来自专利 CN 102920658 B 的多肽。GLP-1 类似物包含该序列。
TP1599 β-Amyloid (1-34) This is a fragment of beta-amyloid peptide. It has amino acids 1 through 34.
T20462 Lysyllysyllysine Lysyllysyllysine is a cationic moiety. It may be used in the construction of gene delivery vectors and DNA nanoparticles.
TP1789 Malantide Malantide is a dodecapeptide phosphorylated by cyclic AMP-dependent protein kinase (PKA), and increases PKA activity.Malantide is a synthetic peptide that is phosphorylated by PKA and is used to measure PKA activity in vitro.
T12370 Pasireotide Pasireotide(SOM 230) is a stable cyclohexapeptide somatostatin mimic that exhibits unique high-affinity binding to human somatostatin receptors (subtypes sst1/2/3/4/5, pKi=8.2/9.0/9.1/<7.0/9.9 respectively).
TP1045 Orexin B, rat, mouse Orexin B, rat, mouse is an endogenous agonist at Orexin receptor with Kis of 420 and 36 nM for OX1 and OX2, respectively.
TP1286 Carcinoembryonic Antigen CEA Carcinoembryonic Antigen CEA 是一种广谱性肿瘤标志物,是大肠癌组织产生的一种糖蛋白,作为抗原可引起患者的免疫反应。
TP1806L BCMA72-80 acetate(2293841-58-2 free base) BCMA72-80 acetate is a HLA-A2 specific B cell maturation antigen (BCMA) peptide. It is used to study multiple myeloma and tumors, which expresses B cell maturation antigen.
T15368 Galantide Galantide is a reversible and non-specific antagonist of galanin receptor.
TP1732L Galanin (1-30), human acetate Galanin (1-30), human acetate 是一种 30 个氨基酸的神经肽。 它是 GalR1 和 GalR2 受体的激动剂,Kis 均为 1 nM。
T14932 Ceruletide Ceruletide 是一种十肽,是一种安全有效的胆囊收缩剂,是一种胆囊收缩素受体激动剂,对胆囊肌肉和胆管有直接的痉挛性作用。
TP1847 GLGPNPCRKKCYKRDFLGR GLGPNPCRKKCYKRDFLGR is a synthetic peptide.
TP1823 Somatostatin-28 (1-14) Somatostatin-28 (1-14) is an N-terminal fragment of the neuropeptide somatostatin-28. Somatostatin 28 arises from the posttranslational cleavage of prosomatostatin, which in turn is derived from a large precursor, preprosomatostatin.
T5589 H-Gly-Pro-OH H-Gly-Pro-OH 是胶原蛋白代谢的最终产物,能够被脯氨肽酶进一步裂解。
T2584 Octreotide Octreotide 是一种有效的生长激素、胰高血糖素和胰岛素抑制剂。它主要与生长抑素 2、3 和 5 亚型受体结合,可增强 Gi 活性,降低胞内 cAMP 的产生。
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