人内源代谢化合物库

Human Endogenous Metabolite Library

产品编号： L2500

人体内源代谢产物，即人体内产生和发现的一些代谢产物，主要包括糖类、生物活性肽类、核苷和核酸、内源性调节因子、细胞因子和蛋白质等，这些代谢产物往往参与机体重要的生理过程，发挥一定的生理功能和生物学活性。人内源代谢产物可以用作疾病标记物，比如在癌症研究领域，基于肿瘤细胞内、外相关特征性小分子代谢标记物的异常变化来诊断恶性肿瘤、进行药物筛选、评价药物毒性等的方法逐渐成为研究热点。除了用作疾病标记物，人体内源性化合物本身还发挥着十分重要的生理作用，并且大量研究结果证实，许多疾病和内源性物质的异常改变密切相关，因而，从研究内源性活性物质入手来寻找治疗疾病的药物，成为新药研究主要的途径之一。 TargetMol人内源代谢化合物库精选 508个人内源性代谢产物，这些代谢物均来源于人体，是探索疾病发病机制和寻找新药的有效工具。

陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。

产品规格

技术资料

陶术生物化合物库目录(28.1MB)

库化合物信息

Excel

SDF

产品描述

508种人内源性代谢产物的独特集合，可用于高通量、高内涵筛选；
部分产品已上市或进入临床，具有生物安全保障和良好的生物活性；
种类多样：包括羧酸、氨基酸、生物胺、多胺、核苷酸、辅酶和维生素、糖类、脂肪酸、脂类、类固醇和激素等不同种类代谢相关产物；
信息详细：包括化合物分子式、分子量、SMILES、产品描述、化合物种类、细胞分布、生物样本分布、组织分布、相关疾病及参考文献等；
NMR、HPLC/LCMS等多种检测技术保证产品结构正确，纯度高，减少假阳性。

化合物库定制

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化合物库组成

Endogenous Metabolite (471)

Apoptosis (19)

Autophagy (18)

Antibacterial (16)

DNA/RNA Synthesis (10)

Reactive Oxygen Species (9)

Nucleoside Antimetabolite/Analog (9)

Estrogen/progestogen Receptor (9)

Amino Acids and Derivatives (9)

Ferroptosis (8)

Influenza Virus (6)

iGluR (6)

GluR (6)

5-HT Receptor (6)

NO Synthase (5)

NMDAR (5)

Antifungal (5)

Antioxidant (4)

Adenosine Receptor (4)

TNF (3)

Thyroid hormone receptor(THR) (3)

ROS (3)

PPAR (3)

Phosphatase (3)

Mitophagy (3)

Glucocorticoid Receptor (3)

GABA Receptor (3)

FXR (3)

Estrogen Receptor/ERR (3)

Dopamine Receptor (3)

Dehydrogenase (3)

Cannabinoid Receptor (3)

Arginase (3)

AhR (3)

TRP/TRPV Channel (2)

Transferase (2)

Reductase (2)

Prostaglandin Receptor (2)

Progesterone Receptor (2)

Potassium Channel (2)

PKC (2)

NOD (2)

MMP (2)

Imidazoline Receptor (2)

HSV (2)

HMG-CoA Reductase (2)

GPCR19 (2)

Glutathione reductase (2)

Chloride channel (2)

Caspase (2)

ATPase (2)

Aryl Hydrocarbon Receptor (2)

Anti-infection (2)

Antibiotic (2)

AMPK (2)

AChR (2)

Xanthine Oxidase (1)

Wnt/beta-catenin (1)

Virus Protease (1)

Tyrosinase (1)

Trk receptor (1)

Somatostatin (1)

ROR (1)

Reverse Transcriptase (1)

Retinoid Receptor (1)

PKA (1)

PARP (1)

P450 (1)

p38 MAPK (1)

P2Y Receptor (1)

P2X Receptor (1)

Oxytocin Receptor (1)

Opioid Receptor (1)

Nrf2 (1)

NF-κB (1)

Neurokinin receptor (1)

NADPH (1)

mTOR (1)

MT Receptor (1)

MRP (1)

Mitochondrial Metabolism (1)

Microtubule Associated (1)

Melatonin Receptor (1)

MAO (1)

Liver X Receptor (1)

LDL (1)

IL Receptor (1)

HSP (1)

HIV Protease (1)

Histamine Receptor (1)

HIF (1)

GlyT (1)

Glutathione Peroxidase (1)

FGFR (1)

Fatty Acid Synthase (1)

ERK (1)

Drug Metabolite (1)

DNA Methyltransferase (1)

DHFR (1)

Decarboxylase (1)

Cysteine Protease (1)

Carbonic Anhydrase (1)

CaMK (1)

Calcium Channel (1)

Bradykinin Receptor (1)

Beta Amyloid (1)

Antifection (1)

Androgen Receptor (1)

Akt (1)

Adrenergic Receptor (1)

AChE (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

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