人内源代谢化合物库 Plus

Human Endogenous Metabolite Compound Library Plus

产品编号： L2501

研究表明生物体受刺激或扰动后（如低氧、营养物质、药物等）代谢产物会发生变化，基于肿瘤细胞内、外相关特征性小分子代谢标记物的异常变化来诊断恶性肿瘤、进行药物筛选、评价药物毒性等的方法也逐渐成为研究热点。癌细胞具有一种独特的、有别于正常细胞的代谢表型，监测癌细胞代谢过程中小分子代谢物的波动情况，将有利于预测肿瘤的进展、了解体内物质代谢途径、探索癌症发病机制及药物作用机制等。目前的研究主要集中于与癌细胞能量代谢相关的化合物研究，如核苷类、氨基酸类、脂类、糖类等。例如，已发现多种与肿瘤相关的脂类标记物，胆碱、磷酸胆碱、磷酸卵磷脂、胆固醇等脂类变化谱是细胞膜破坏的标志；丙酮酸、乳酸、异丁酸等是与肿瘤细胞糖代谢相关的生物标记物，探索通过靶向脂代谢、糖代谢途径治疗恶性肿瘤的策略正备受关注。

TargetMol 人内源代谢化合物库由1300种与内源代谢相关的生物活性化合物组成，可用于研究内源性代谢疾病和新药筛选。

陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。

产品规格

技术资料

陶术生物化合物库目录(28.1MB)

库化合物信息

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产品描述

1300种内源性生物活性化合物的独特集合，用于高通量、高内涵筛选；
研究人体代谢疾病、探索癌症发病机制和寻找新药的有效工具；
部分产品已上市或进入临床，具有生物安全保障和良好的生物活性；
结构多样，药效显著，可渗透细胞；
详细的说明书，化合物结构、活性描述等；
NMR、HPLC/LCMS等多种检测技术保证产品结构正确，纯度高，减少假阳性。

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化合物库组成

Endogenous Metabolite (820)

Apoptosis (113)

Autophagy (80)

Antibacterial (71)

Reactive Oxygen Species (41)

NF-κB (41)

Antifungal (36)

Antioxidant (26)

COX (24)

DNA/RNA Synthesis (23)

P450 (21)

Influenza Virus (20)

PPAR (19)

Antibiotic (18)

HIV Protease (17)

Ferroptosis (17)

Estrogen/progestogen Receptor (15)

ERK (14)

Parasite (13)

GABA Receptor (13)

Amino Acids and Derivatives (12)

Estrogen Receptor/ERR (12)

Nucleoside Antimetabolite/Analog (12)

HSV (12)

5-HT Receptor (12)

TNF (12)

Mitophagy (11)

Caspase (11)

TRP/TRPV Channel (11)

AChR (10)

Dehydrogenase (9)

PI3K (9)

Calcium Channel (9)

Akt (9)

NO Synthase (9)

JNK (8)

iGluR (8)

MMP (8)

Prostaglandin Receptor (8)

Beta Amyloid (8)

AMPK (8)

Dopamine Receptor (7)

p38 MAPK (7)

Virus Protease (7)

NMDAR (7)

ROS (7)

GluR (7)

Nrf2 (7)

Potassium Channel (7)

Anti-infection (7)

Adenosine Receptor (6)

Phosphatase (6)

PKC (6)

IL Receptor (6)

Tyrosinase (6)

Reductase (5)

Adrenergic Receptor (5)

MAO (5)

Drug Metabolite (5)

Mitochondrial Metabolism (5)

Opioid Receptor (5)

BCL (5)

Lipoxygenase (5)

AChE (5)

STAT (5)

Cannabinoid Receptor (5)

Thyroid hormone receptor(THR) (4)

Proteasome (4)

Chloride channel (4)

ATPase (4)

NOS (4)

Arginase (4)

Histamine Receptor (4)

Progesterone Receptor (4)

PKA (4)

PARP (4)

FXR (4)

Aryl Hydrocarbon Receptor (4)

Glucocorticoid Receptor (4)

Interleukin (4)

Antiviral (4)

Sirtuin (4)

GPR (4)

Transferase (3)

Serotonin Transporter (3)

Topoisomerase (3)

PDE (3)

Glucosidase (3)

Xanthine Oxidase (3)

Norepinephrine (3)

TGF-beta/Smad (3)

EGFR (3)

P-gp (3)

SARS-CoV (3)

TLR (3)

Platelet aggregation (3)

HMG-CoA Reductase (3)

Microtubule Associated (3)

HIF/HIF Prolyl-Hydroxylase (3)

AhR (3)

Carbonic Anhydrase (2)

ROR (2)

P2Y Receptor (2)

RAAS (2)

GSK-3 (2)

Melatonin Receptor (2)

Wnt/beta-catenin (2)

Serine/threonin kinase (2)

Glucokinase (2)

VEGFR (2)

E1/E2/E3 Enzyme (2)

UGT (2)

Gamma-secretase (2)

LDL (2)

CDK (2)

MT Receptor (2)

Phosphorylase (2)

Antifection (2)

Fatty Acid Synthase (2)

Bombesin Receptor (2)

JAK (2)

FAAH (2)

CaMK (2)

mTOR (2)

Androgen Receptor (2)

ATP Citrate Lyase (2)

MAPK (2)

Glutathione reductase (2)

Acyltransferase (2)

Trk receptor (2)

GPCR19 (2)

Histone Acetyltransferase (2)

GST (2)

Retinoid Receptor (2)

HDAC (2)

ribosome (2)

Aromatase (2)

Phospholipase (2)

HIF (2)

MEK (2)

Neurokinin receptor (2)

Syk (2)

NOD (2)

DNA Methyltransferase (2)

Imidazoline Receptor (2)

p53 (2)

HER (2)

Proton pump (1)

Transaminase (1)

stilbene oxidase (1)

CD38 (1)

DHFR (1)

CYP19A1 (1)

Integrin (1)

LTR (1)

BACE (1)

IFNAR (1)

aconitase (1)

DYRK (1)

NADPH (1)

Histone Demethylase (1)

Lipase (1)

Glutathione Peroxidase (1)

c-Myc (1)

ABC (1)

CaSR (1)

MRP (1)

GNRH Receptor (1)

HBV (1)

Cysteine Protease (1)

Liver X Receptor (1)

Leukotriene Receptor (1)

Amylase (1)

IAP (1)

Immunology/Inflammation related (1)

PAFR (1)

Fas/FasL (1)

P2X Receptor (1)

GlyT (1)

Hexokinase (1)

Hedgehog/Smoothened (1)

Bradykinin Receptor (1)

CXCR (1)

PTEN (1)

Somatostatin (1)

Epoxide Hydrolase (1)

cAMP (1)

Epigenetic Reader Domain (1)

DUB (1)

Telomerase (1)

SGLT (1)

Lipid (1)

PGE Synthase (1)

HSP (1)

Aminopeptidase (1)

Free radical scavengers (1)

transporter (1)

Decarboxylase (1)

Casein Kinase (1)

RSV (1)

IκB/IKK (1)

Carboxypeptidase (1)

Reverse Transcriptase (1)

PDK (1)

Oxytocin Receptor (1)

PLK (1)

FGFR (1)

Sodium Channel (1)

IRAK (1)

Sigma receptor (1)

Thrombin (1)

NOD-like Receptor (NLR) (1)

ROS Kinase (1)

CFTR (1)

Monoamine Oxidase (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

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