糖苷模拟物预制化合物库

Glycomimetics Pre-Plated Set

产品编号： AN1700

Glycomimetics Pre-Plated Set 包含 2430种化合物 ASINEX 开发了一种强大的合成技术，可以高效地构建拟糖化合物合成库。这些化合物通过呈现特定的药效基团和片段来模拟碳水化合物的有利结合特性。Glycomimetics Pre-Plated Set 包含 2430 种化合物。

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Product Description 产品描述

Product Description

Cyclic amino alcohols and cyclic glycols are the common structural features of carbohydrates and other functional small molecules found in nature. Carbohydrates and their mimics constitute very important protein recognition elements as confirmed by multiple co-crystal structures published in PDB. Analysis of literature data revealed 40 approved carbohydrate-based or carbohydrate-like drugs with 283 distinct mechanisms of action across 50 categories including antineoplastic, antiviral, antibacterial, antifungal, and cardiotonic agents as well as essential vitamins and micronutrients. The Glycomimetic library exhibits remarkable chemical diversity to provide broad target applicability in modulating GPCRs, protein-protein interactions, ion channels, antibacterial and antiviral targets.

Example of structure：

"环状氨基醇和环状乙二醇是自然界中糖类和其他功能性小分子的共同结构特征。糖类及其模拟物在蛋白质识别中起着非常重要的作用，这一点已被发表在 PDB 上的多个共晶体结构所证实。对文献数据的分析表明，有 40 种已获批准的基于糖类或类似糖类的药物，其 283 种不同的作用机制涉及 50 个类别，包括抗肿瘤、抗病毒、抗菌、抗真菌、强心剂以及必需维生素和微量营养素。Glycomimetic库具有显著的化学多样性，在调节 GPCRs、蛋白-蛋白相互作用、离子通道、抗菌和抗病毒靶点方面具有广泛的适用性。结构示例：[提供具体结构示例]

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化合物库组成

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

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