抗衰老化合物库 | 陶术生物

抗衰老化合物库

Anti-Aging Compound Library

产品编号： L8200

什么是衰老？衰老是一个由多种因素引起的自然过程。影响生物衰老的因素主要分为两大类：自主调节和损害相关。自主调节依赖特定基因表达，调节机体生长发育过程。损害相关包括内部和环境因素对生物体的损伤作用，损伤理论提出了12种衰老在生物体中的代谢“标志”：基因组不稳定性；端粒损耗；表观遗传改变；蛋白质老化；营养能量代谢障碍；线粒体功能障碍；细胞衰老；干细胞耗竭；细胞间通讯改变；慢性炎症；肠道微生物失调；巨自噬失活。

“永葆青春”是人类经久不衰的话题，如何延缓衰老也是科学家广泛关注的课题。TargetMol 的抗衰老化合物库可以为您提供抗衰老研究的利器，这些化合物都已通过前期临床研究和临床实验，生物活性和安全性得到验证，可以大大加快研发和优化的速度，相信会成为您开展药物筛选的理想工具。

陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。

产品规格

技术资料

陶术生物化合物库目录(28.1MB)

库化合物信息

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产品描述

3324个抗衰老化合物的独特集合，可用于高通量筛选和高内涵筛选；
通过前期临床研究和临床实验，生物活性和安全性得到验证；
涵盖衰老相关的各个过程，具有保护细胞，防止DNA损伤，促进干细胞生成等作用；
详细的说明书，化合物结构、靶点信息、IC50值、活性描述等；
NMR和HPLC技术保证产品高纯度；
所有化合物现货供应。

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化合物库组成

Apoptosis (616)

Autophagy (581)

COX (250)

Endogenous Metabolite (236)

Antibacterial (221)

NF-κB (165)

DNA/RNA Synthesis (133)

PI3K (129)

Reactive Oxygen Species (124)

Antibiotic (123)

P450 (121)

mTOR (91)

Antioxidant (87)

CDK (83)

TNF (78)

HDAC (76)

ERK (76)

AMPK (75)

Antifungal (71)

p38 MAPK (69)

Parasite (68)

HIV Protease (66)

JAK (65)

Akt (64)

PPAR (61)

Epigenetic Reader Domain (60)

Ferroptosis (60)

STAT (57)

Topoisomerase (57)

Influenza Virus (56)

Mitochondrial Metabolism (55)

Mitophagy (55)

Sirtuin (51)

Wnt/beta-catenin (49)

Histone Methyltransferase (48)

Estrogen/progestogen Receptor (47)

PARP (45)

Prostaglandin Receptor (43)

BCL (43)

Microtubule Associated (42)

Calcium Channel (39)

JNK (39)

SARS-CoV (38)

ROS (38)

NO Synthase (38)

EGFR (37)

p53 (36)

GSK-3 (36)

PKC (36)

HSP (36)

IGF-1R (36)

Caspase (36)

IL Receptor (35)

Nucleoside Antimetabolite/Analog (35)

Virus Protease (35)

Dehydrogenase (34)

MMP (33)

Potassium Channel (33)

FLT (33)

VEGFR (33)

AChR (33)

Tyrosine Kinases (32)

Tyrosinase (32)

Estrogen Receptor/ERR (32)

TGF-beta/Smad (32)

HSV (31)

Src (31)

Aurora Kinase (30)

DNA-PK (30)

Glucocorticoid Receptor (28)

IκB/IKK (28)

5-HT Receptor (27)

HIF/HIF Prolyl-Hydroxylase (27)

Adrenergic Receptor (27)

Proteasome (26)

E1/E2/E3 Enzyme (26)

ALK (25)

Nrf2 (25)

MEK (25)

Lipoxygenase (24)

DUB (23)

PDGFR (23)

ROCK (23)

S6 Kinase (22)

FGFR (22)

Casein Kinase (22)

NOS (22)

HCV Protease (22)

PKA (22)

AChE (21)

DNA Alkylator/Crosslinker (20)

Gamma-secretase (20)

PDE (20)

Beta Amyloid (20)

Histamine Receptor (19)

Mdm2 (19)

ATM/ATR (19)

Hedgehog/Smoothened (19)

Dopamine Receptor (19)

Interleukin (18)

MAPK (18)

Sodium Channel (18)

Histone Demethylase (17)

Bcr-Abl (17)

TRP/TRPV Channel (17)

Carbonic Anhydrase (17)

GABA Receptor (17)

c-Kit (16)

Reverse Transcriptase (16)

HIF (15)

Phospholipase (15)

ATPase (15)

PLK (14)

Raf (14)

MAO (14)

Phosphatase (14)

DNA Alkylation (14)

Anti-infection (13)

Cysteine Protease (13)

PERK (13)

NADPH (13)

Smo (13)

HBV (13)

P-gp (13)

Drug Metabolite (12)

Serine/threonin kinase (12)

c-Met/HGFR (12)

Progesterone Receptor (12)

FAK (12)

TLR (12)

Trk receptor (12)

Antifolate (12)

Chk (12)

Monoamine Oxidase (11)

Glutathione Peroxidase (11)

Serine Protease (10)

PDK (10)

Antiviral (10)

Syk (10)

DNA Methyltransferase (10)

RAAS (10)

Retinoid Receptor (10)

Ras (10)

DNA gyrase (10)

Kinesin (10)

BACE (10)

DNA (10)

Histone Acetyltransferase (10)

Adenosine Receptor (9)

IRE1 (9)

Telomerase (9)

DPP-4 (9)

transporter (9)

c-RET (9)

NOD (9)

PGE Synthase (9)

CXCR (8)

CaMK (8)

NOD-like Receptor (NLR) (8)

Pim (8)

DHFR (8)

GPR (8)

Androgen Receptor (8)

iGluR (8)

HER (8)

Thrombin (8)

LRRK2 (8)

Porcupine (7)

IAP (7)

Proton pump (7)

Reductase (7)

PTEN (7)

Xanthine Oxidase (7)

CAT (7)

PAK (7)

MRP (6)

ROS Kinase (6)

Antifection (6)

Beta-Secretase (6)

UGT (6)

Chloride channel (6)

Fatty Acid Synthase (6)

ribosome (6)

Opioid Receptor (6)

BTK (6)

NADPH-oxidase (5)

Lipase (5)

TAM Receptor (5)

Ligand for E3 Ligase (5)

CRISPR/Cas9 (5)

GluR (5)

Factor Xa (5)

RIP kinase (5)

Free radical scavengers (5)

Glucokinase (5)

Amino Acids and Derivatives (5)

NMDAR (5)

HMG-CoA Reductase (5)

Transferase (5)

p97 (5)

Aryl Hydrocarbon Receptor (5)

c-Fms (4)

Cannabinoid Receptor (4)

RSV (4)

YAP (4)

S1P Receptor (4)

Aromatase (4)

DYRK (4)

OCT (4)

PYK2 (4)

Norepinephrine (4)

P2X Receptor (4)

TOPK (4)

GST (4)

SIK (4)

CCR (4)

Immunology/Inflammation related (4)

Epoxide Hydrolase (4)

PI4K (4)

FXR (4)

LIM Kinase (4)

IFNAR (4)

Serotonin Transporter (4)

OXPHOS (4)

Glucosidase (4)

MLK (4)

Leukotriene Receptor (3)

Ligands for Target Protein for PROTAC (3)

Hexokinase (3)

Guanylate cyclase (3)

Integrin (3)

BMI-1 (3)

MTH1 (3)

Annexin A (3)

GRK (3)

Molecular Glues (3)

Dynamin (3)

Arginase (3)

cell cycle arrest (3)

SGK (3)

ABC (3)

AhR (3)

FAAH (3)

Acyltransferase (3)

P2Y Receptor (3)

KSP (2)

Tie-2 (2)

LDL (2)

PKM (2)

ROR (2)

Wee1 (2)

Monocarboxylate transporter (2)

advanced glycation end products (2)

OAT (2)

IRAK (2)

ATP Citrate Lyase (2)

Glutaminase (2)

Imidazoline Receptor (2)

CFTR (2)

Rho (2)

LPL Receptor (2)

Platelet aggregation (2)

Adenosine deaminase (2)

Survivin (2)

ASK (2)

Neprilysin (2)

FLAP (2)

SGLT (2)

NPC1L1 (2)

CSF-1R (2)

Sigma receptor (2)

Carboxypeptidase (2)

Lipid (2)

GPX (2)

Liver X Receptor (2)

APC (2)

MNK (2)

GluCls (2)

NAMPT (2)

Myosin (2)

STING (2)

ACK (2)

PAI-1 (2)

Melatonin Receptor (2)

lysosomal autophagy (2)

RAR/RXR (1)

aconitase (1)

Somatostatin (1)

stilbene oxidase (1)

Thyroid hormone receptor(THR) (1)

GSNOR (1)

Pyroptosis (1)

MyD88 (1)

VDAC (1)

Glutathione reductase (1)

BCRP (1)

Adiponectin receptor (1)

IDO (1)

Stearoyl-CoA Desaturase (SCD) (1)

Integrase (1)

Indoleamine 2,3-Dioxygenase (IDO) (1)

PAFR (1)

Amylase (1)

cholecystokinin (1)

Hippo pathway (1)

Anion Exchanger (1)

MALT (1)

Discoidin Domain Receptor (DDR) (1)

Aminopeptidase (1)

Bombesin Receptor (1)

Glucagon Receptor (1)

Transaminase (1)

Ephrin Receptor (1)

LTR (1)

hCE (1)

KLF (1)

Adenylyl cyclase (1)

N-Acetylglucosaminyltransferase (1)

RANKL/RANK (1)

Complement System (1)

Hydrogenase (1)

CaSR (1)

Thioredoxin (1)

Protease-activated Receptor (1)

Na+/Ca2+ Exchanger (1)

Gap Junction Protein (1)

PD-1/PD-L1 (1)

VDA (1)

Stemness kinase (1)

PROTAC Linker (1)

Hydroxylase (1)

PAD (1)

CYP19A1 (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

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