CD32B Protein, Mouse, Recombinant (His)

Low affinity immunoglobulin gamma Fc region receptor II (CD32B) is a single-pass type I membrane protein and contains 2 Ig-like C2-type (immunoglobulin-like) domains. The inhibitory CD32B is expressed on B cells and myeloid dendritic cells. Ligation of CD32B on B cells downregulates antibody production and may, in some circumstances, promote apoptosis. Co-ligation of CD32B on dendritic cells inhibits maturation and blocks cell activation. CD32B may also be a target formonoclonal antibody therapy for malignancies.

规格	价格/CNY		数量
10 μg	￥ 740	5日内发货
50 μg	￥ 1,970	5日内发货
500 μg	￥ 12,100	5日内发货
1 mg	￥ 17,400	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 740

5日内发货

50 μg

￥ 1,970

5日内发货

500 μg

￥ 12,100

5日内发货

1 mg

￥ 17,400

5日内发货

生物活性

Loaded Mouse CD32-His on HIS1K Biosensor, can bind Anti-Human HER2 mAb with an affinity constant of 1.14 uM as determined in BLI assay. (Regularly tested)

产品描述

种属	Mouse
表达系统	HEK293 Cells
标签	C-6xHis
蛋白编号	P08101
别名	Fcgr2, Fcgr2b, Fc-γ-RIIB, Fc-γ RII, Low affinity immunoglobulin γ Fc region receptor II, Fc gamma receptor IIB, Low affinity immunoglobulin gamma Fc region receptor II, Fc γ receptor IIB, Ly-17, Fc-gamma RII, FcRII, IgG Fc receptor II beta, CD32, IgG Fc receptor II β, Lymphocyte antigen 17, Fc-gamma-RIIB
氨基酸序列	Thr30-Pro210
蛋白构建	Thr30-Pro210
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量	33 KDa (reducing condition)

内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Low affinity immunoglobulin gamma Fc region receptor II (CD32B) is a single-pass type I membrane protein and contains 2 Ig-like C2-type (immunoglobulin-like) domains. The inhibitory CD32B is expressed on B cells and myeloid dendritic cells. Ligation of CD32B on B cells downregulates antibody production and may, in some circumstances, promote apoptosis. Co-ligation of CD32B on dendritic cells inhibits maturation and blocks cell activation. CD32B may also be a target formonoclonal antibody therapy for malignancies.

计算器

复溶计算器

重组蛋白稀释计算器

比活力计算器

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

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CD32B Protein, Mouse, Recombinant (His)

计算器

技术支持

Keywords