TIE2 Protein, Human, Recombinant (aa 23-745, His)

TIE2 Protein, Human, Recombinant (aa 23-745, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 100-120 KDa and the accession number is Q02763-1.

规格	价格/CNY		数量
10 μg	￥ 330	5日内发货
50 μg	￥ 1,010	5日内发货
500 μg	￥ 5,530	5日内发货
1 mg	￥ 8,300	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 330

5日内发货

50 μg

￥ 1,010

5日内发货

500 μg

￥ 5,530

5日内发货

1 mg

￥ 8,300

5日内发货

产品描述	TIE2 Protein, Human, Recombinant (aa 23-745, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 100-120 KDa and the accession number is Q02763-1.

种属	Human
表达系统	HEK293 Cells
标签	C-6xHis
蛋白编号	Q02763-1
别名	VMCM1, TEK, Tie2, hTIE2, p140 TEK, soluble TIE2 variant 2, CD202b antigen, VMCM, TEK tyrosine kinase, endothelial, CD202b, EC 2.7.10.1, angiopoietin-1 receptor, EC 2.7.10, Tie-2, soluble TIE2 variant 1
氨基酸序列	Ala23-Lys745
蛋白构建	Ala23-Lys745
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量	100-120 KDa (reducing condition)

内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Tie-1/Tie (tyrosine kinase with Ig and EGF homology domains 1) and Tie-2/Tek comprise a receptor tyrosine kinase (RTK) subfamily with unique structural characteristics: two immunoglobulin-like domains flanking three epidermal growth factor (EGF)-like domains and followed by three fibronectin type III-like repeats in the extracellular region and a split tyrosine kinase domain in the cytoplasmic region. These receptors are expressed primarily on endothelial and hematopoietic progenitor cells and play critical roles in angiogenesis, vasculogenesis and hematopoiesis. Human Tie-2 cDNA encodes a 1124 amino acid (aa) residue precursor protein with an 18 residue putative signal peptide, a 727 residue extracellular domain and a 354 residue cytoplasmic domain. Two ligands, angiopoietin-1 (Ang-1) and angiopoietin-2 (Ang-2), which bind Tie-2 with high-affinity have been identified. Ang-2 has been reported to act as an antagonist for Ang-1. Mice engineered to overexpress Ang-2 or to lack Ang-1 or Tie-2 display similar angiogenesis defects.

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TIE2 Protein, Human, Recombinant (aa 23-745, His)

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