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MASP2 Protein, Cynomolgus, Recombinant (His)

MASP2 Protein, Cynomolgus, Recombinant (His)

产品编号 TMPK-00496
别名: MAP19, MASP1P1, MASP-2, sMap

MASP2 Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 46.8 kDa and the accession number is A0A2K5UJY0.

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MASP2 Protein, Cynomolgus, Recombinant (His)
规格 价格/CNY 货期 数量
100 μg ¥ 3,990 5日内发货
500 μg ¥ 16,000 5日内发货
1 mg ¥ 26,700 5日内发货
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产品目录号及名称: MASP2 Protein, Cynomolgus, Recombinant (His) (TMPK-00496)
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生物活性
技术参数
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参考文献
生物活性 Immobilized Cynomolgus MASP2, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Anti-MASP2 Antibody, hFc Tag with the EC50 of 10.4ng/ml determined by ELISA.
产品描述 MASP2 Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 46.8 kDa and the accession number is A0A2K5UJY0.
种属 Cynomolgus
表达系统 E. coli
标签 C-His
蛋白编号 A0A2K5UJY0
别名 MAP19, MASP1P1, MASP-2, sMap
蛋白构建 Thr287-Phe686
蛋白纯度 > 95% as determined by Tris-Bis PAGE
分子量 46.8 kDa (predicted). Due to autocatalytic cleavage, the protein migrates to 21-24 kDa&28-30 kDa based on Tris-Bis PAGE result.
内毒素 < 1 EU/μg by the LAL method.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris, 200 mM NaCl (pH 9.0). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法 Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice.

研究背景 The dysregulation of complement cascade leads to unsolicited cytokine storm, inflammation, deterioration of alveolar lining cells, culminating in acquired respiratory destructive syndrome (ARDS). Similar pathogenesis is observed with the middle east respiratory syndrome (MERS), severe acquired respiratory syndrome (SARS), and SARS-CoV-2. Activation of the lectin pathway via mannose-binding lectin associated serine protease 2 (MASP2) is witnessed under discrete viral infections including COVID-19.

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Keywords

MASP2 Protein, Cynomolgus, Recombinant (His) MAP 19 MASP 2 MAP19 MASP1P1 MASP-2 sMap MASP2 MAP-19 recombinant recombinant-proteins proteins protein

 

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