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Complement Factor D/CFD Protein, Mouse, Recombinant (hFc)

Complement Factor D/CFD Protein, Mouse, Recombinant (hFc)

产品编号 TMPK-00151
别名: C3 convertase activator, AMBP-1, PFD, FACTOR D, CFD, ADN, EC 3.4.21.46, Complement factor D, DF, EC 3.4.21, Adipsin

Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium. Complement Factor D/CFD Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 52.2 kDa and the accession number is P03953-1.

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Complement Factor D/CFD Protein, Mouse, Recombinant (hFc)
规格 价格/CNY 货期 数量
100 μg ¥ 3,400 5日内发货
500 μg ¥ 13,600 5日内发货
1 mg ¥ 22,700 5日内发货
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产品目录号及名称: Complement Factor D/CFD Protein, Mouse, Recombinant (hFc) (TMPK-00151)
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参考文献
产品描述 Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium. Complement Factor D/CFD Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 52.2 kDa and the accession number is P03953-1.
种属 Mouse
表达系统 HEK293 Cells
标签 C-hFc
蛋白编号 P03953-1
别名 C3 convertase activator, AMBP-1, PFD, FACTOR D, CFD, ADN, EC 3.4.21.46, Complement factor D, DF, EC 3.4.21, Adipsin
蛋白构建 Ile26-Ser259
蛋白纯度 > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量 52.2 kDa (predicted). Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
内毒素 < 1 EU/μg by the LAL method.
缓冲液 Supplied as 0.22 μm filtered solution in 20 mM Tris, 500 mM NaCl (pH 7.4).
存储

It is recommended to store the product under sterile conditions at -70℃ or lower. Samples are stable for up to 12 months at -80℃. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium.

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Keywords

Complement Factor D/CFD Protein, Mouse, Recombinant (hFc) C3 convertase activator AMBP-1 PFD AMBP1 FACTOR D AMBP 1 CFD ADN EC 3.4.21.46 Complement factor D DF EC 3.4.21 Adipsin recombinant recombinant-proteins proteins protein

 

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