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CD28 Protein, Mouse, Recombinant (hFc & His)

CD28 Protein, Mouse, Recombinant (hFc & His)

产品编号 TMPJ-00099
别名: T-cell-specific surface glycoprotein CD28, CD28

T-cell-specific surface glycoprotein CD28, contains an Ig-like V-type domain. CD28 is one of the proteins expressed on T cells that provide co-stimulatory signals, which are required for their activation. It is the receptor for CD80 and CD86. When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells. It involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.

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CD28 Protein, Mouse, Recombinant (hFc & His)
规格 价格/CNY 货期 数量
10 μg ¥ 220 5日内发货
50 μg ¥ 620 5日内发货
500 μg ¥ 3,190 5日内发货
1 mg ¥ 4,340 5日内发货
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产品目录号及名称: CD28 Protein, Mouse, Recombinant (hFc & His) (TMPJ-00099)
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产品描述 T-cell-specific surface glycoprotein CD28, contains an Ig-like V-type domain. CD28 is one of the proteins expressed on T cells that provide co-stimulatory signals, which are required for their activation. It is the receptor for CD80 and CD86. When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells. It involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.
种属 Mouse
表达系统 HEK293 Cells
标签 C-hFc-6xHis
蛋白编号 P31041
别名 T-cell-specific surface glycoprotein CD28, CD28
氨基酸序列 Asn20-Lys149
蛋白构建 Asn20-Lys149
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量 60 KDa (reducing condition)
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, pH 7.4.
复溶方法 Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 T-cell-specific surface glycoprotein CD28, contains an Ig-like V-type domain. CD28 is one of the proteins expressed on T cells that provide co-stimulatory signals, which are required for their activation. It is the receptor for CD80 and CD86. When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells. It involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.

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Keywords

CD28 Protein, Mouse, Recombinant (hFc & His) CD-28 T-cell-specific surface glycoprotein CD28 CD28 CD 28 recombinant recombinant-proteins proteins protein

 

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