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AGRP Protein, Rhesus, Recombinant (mFc)

AGRP Protein, Rhesus, Recombinant (mFc)

产品编号 TMPY-00630
别名: agouti related neuropeptide

AGRP Protein, Rhesus, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 32.3 kDa and the accession number is A0A8J8XRM3.

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AGRP Protein, Rhesus, Recombinant (mFc)
规格 价格/CNY 货期 数量
200 μg ¥ 5,750 5日内发货
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产品目录号及名称: AGRP Protein, Rhesus, Recombinant (mFc) (TMPY-00630)
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生物活性 Testing in progress
产品描述 AGRP Protein, Rhesus, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 32.3 kDa and the accession number is A0A8J8XRM3.
种属 Rhesus
表达系统 HEK293 Cells
标签 N-mFc
蛋白编号 A0A8J8XRM3
别名 agouti related neuropeptide
蛋白构建 The rhesus AGRP (XP_001091740.1) (Ser83-Thr132) was expressed with the Fc region of Mouse IgG1 at the N-terminus.
蛋白纯度 > 90 % as determined by SDS-PAGE
分子量 32.3 kDa (predicted)
内毒素 < 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice.

研究背景 Agouti Related Protein (AGRP, or AGRT), is an endogenous antagonist of the melanocortin receptors MC3R and MC4R found in the hypothalamus and exhibits potent orexigenic activity. AGRP can act as a competitive antagonist to proopiomelanocortin (POMC)-derived peptides at the melanocortin-4 receptor (MC4R), and that this homeostatic mechanism is important as a means of coordinating appetite with perceived metabolic requirement. AGRP is upregulated by fasting while intracerebroventricular injections of synthetic AGRP lead to increased appetite and food intake. Thus, AGRP is a powerful orexigenic peptide that increases food intake when ubiquitously overexpressed or when administered centrally.

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Keywords

AGRP Protein, Rhesus, Recombinant (mFc) agouti related neuropeptide recombinant recombinant-proteins proteins protein

 

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