c-Myc

Myc is a family of regulator genes and proto-oncogenes that code for transcription factors. The Myc family consists of three related human genes: c-myc (MYC), l-myc (MYCL), and n-myc (MYCN). c-myc (also sometimes referred to as MYC) was the first gene to be discovered in this family, due to homology with the viral gene v-myc.

Cat. No.	Product Name	CAS No.	Purity
T77939	WBC100 化合物 WBC100	2095780-08-6	98%
T77939	WBC100（14-D-Valine-TPL），一款高效、选择性和具口服活性的c-Myc小分子降解剂，通过针对泛素E3连结酶CHIP介导的26S蛋白酶体途径实现其作用。主要应用于c-Myc过表达肿瘤的研究领域。
T78055	MYC-RIBOTAC 化合物 MYC-RIBOTAC		98%
T78055	MYC-RIBOTAC 是一种针对MYC内部核糖体进入位点（IRES）的核糖核酸酶靶向降解剂（RIBOTAC）。该化合物结合了MYC mRNA的靶向组分以及一种可招募并激活RNA酶L1的小分子。通过降低MYC的mRNA和蛋白质表达水平，MYC-RIBOTAC诱导细胞发生凋亡，应用于抗肿瘤治疗的研究。
T78986	MDEG-541 化合物 MDEG-541		98%
T78986	MDEG-541为一有效MYC-MAX降解剂，展现出显著的抗增殖活性，并有效降低GSPT1、MYC、GSPT2、PLK1蛋白表达水平。
T79438	C-Myc inhibitor 11 化合物 c-Myc inhibitor 11		98%
T79438	c-Myc inhibitor11（Compound 67e），一种c-MYC抑制剂（pEC50: 6.4），在大鼠药代动力学评估中表现出高清除率、中等体积分布和短半衰期，适用于癌症研究领域。
T79439	C-Myc inhibitor 12 化合物 c-Myc inhibitor 12		98%
T79439	c-Myc inhibitor12 (compound 67h)，作为c-Myc抑制剂，具有pEC50值为6.4。
T79872	M-Se3 化合物 m-Se3	2829939-44-6	98%
T79872	m-Se3 为一选择性c-MYC转录抑制剂，有效抑制肿瘤生长且表现出抗癌活性。
T40419	IRES-C11 化合物IRES-C11	342416-30-2	98%
T40419	IRES-C11 is a specific inhibitor of translation that targets the internal ribosome entry site (IRES) of the c-MYC gene. It functions by blocking the interaction ...
TN3708	Coronarin D 化合物 TN3708	119188-37-3	98%
TN3708	Coronarin D shows promising antifungal activity against C. albicans in vitro, the minimum inhibitory concentration (MIC) and the minimum fungicidal concentration...
TN2177	Sanggenol L 桑根醇L	329319-20-2	98%
TN2177	Sanggenol L shows higher cytotoxicity against human oral tumor cell lines (HSC-2 and HSG) than against normal human gingival fibroblasts (HGF), it induces apopto...
TN4582	Moracin T 化合物 TN4582	1146113-27-0	98%
TN4582	Moracin treatment can inhibit the double 12-O-tetradecanoylphorbol 13-acetate (TPA) treatment-induced morphological changes reflecting inflammatory response, inc...
T16839	SAJM589 化合物 T16839	2089-82-9	98%
T16839	sAJM589 is a Myc inhibitor(IC50: 1.8 μM).
T11783	KSI-3716 化合物 T11783	1151813-61-4	98%
T11783	KSI-3716 is an inhibitor of c-Myc.
TN1354	Aaptamine 化合物Aaptamine	85547-22-4	98%
TN1354	Aaptamine functions as a proteasome inhibitor, it activates p21 promoter in a p53-independent manner.
T10702	CBP/p300-IN-2 化合物 T10702	2158265-96-2	98%
T10702	CBP/EP300-IN-2 is an inhibitor of CBP/EP300 (IC50s: 1.07 nM and 5.96 nM for CBP/HTRF and Myc).
TN4581	Moracin D 化合物 TN4581	69120-07-6	98%
TN4581	Moracin C and moracin D, new phytoalexins from diseased mulberry, are antifungal compounds. Moracin may be protective influence in tumor promotion, utilization o...
T60019	VPC-70063 化合物VPC-70063	13571-44-3	99.93%
T60019	VPC-70063 (Thiourea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)-) 是 c-Myc-MAX 的抑制剂。 VPC-70063 的 Myc-Max 转录活性抑制率为 106%，IC50 为 8.9 μM，Myc-Max/UBE2C 下游通路抑...
T0617	Nicotinamide N-oxide 烟酰胺-N-氧化物	1986-81-8	99.9%
T0617	Nicotinamide N-oxide (Nicotinamide 1-oxide) 是生物体内烟酰胺分解代谢物，是高效选择性CXCR2受体拮抗剂。
T3048	10058-F4 化合物10058-F4	403811-55-2	99.82%
T3048	10058-F4 (c-Myc Inhibitor) 是一种细胞渗透性噻唑烷酮，可特异性抑制 c-Myc-Max 相互作用并防止 c-Myc 靶基因表达的反式激活；诱导细胞周期停滞和凋亡。
T9093	NY2267 化合物NY2267	886053-73-2	99.6%
T9093	NY2267 (Acetic acid, 2-[[6-[2-(cyclohexylamino)-1-[[(4-methoxyphenyl)methyl](2-pyridinylcarbonyl)amino]-2-oxoethyl]-2-naphthalenyl]oxy]-, 1,1-dimethylethyl ester...
T4367	Mycro 3 化合物Mycro-3	944547-46-0	99.51%
T4367	Mycro 3 在全细胞分析中对 c-Myc 具有强效选择性，可用于胰腺癌的研究。