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Wee1
T2077 MK-1775 MK-1775 is a small molecule inhibitor of the tyrosine kinase WEE1 (IC50: 5.2 nM, in a cell-free assay); hinders G2 DNA damage checkpoint. Adavosertib selectively targets and inhibits WEE1, a tyrosine kinase that phosphorylates cyclin-dependent kinase 1 (CDK1, CDC2) to inactivate the CDC2/cyclin B co
T6931 PD0166285 PD0166285 is a potent Wee1 and Chk1 inhibitor with activity at nanomolar concentrations.PD0166285 is a novel G2 checkpoint abrogator.
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