||Finasteride is an oral inhibitor of active testosterone 5-alpha-reductase and Ki value is 10 nM.
||Isoliquiritigenin, an anti-tumor flavonoid from the root of Glycyrrhiza glabra, suppresses aldose reductase (IC50=320 nM).
||Dexamethasone is a synthetic adrenal corticosteroid with potent anti-inflammatory properties.
||Epalrestat, an aldose reductase inhibitor, is well tolerated in Long-term therapy. It can effectually ameliorate the associated symptoms of diabetic neuropathy and delay the progression of the disease, particularly in patients with limited microangiopathy and good glycemic control.
||Dutasteride is a 5-alpha-reductase inhibitor that inhibits both type-1 and type2 isoforms of the enzyme and is used to treat benign prostatic hyperplasia.
||Ponalrestat is an aldose reductase inhibitor.
||Tectoridin possesses an estrogenic and thyroid hormone-like agent by activating estrogen and thyroid hormone receptors. Tectoridin has anti-oxidant, anti-inflammatory and hypoglycemic activities; Tectoridin and its five metabolites inhibits the activities of lens aldose reductase in rat (IC₅₀: 1
||GinsenosideRo exhibits a Ca2+-antagonistic antiplatelet effect.