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Reductase
T0488 Finasteride Finasteride is an oral inhibitor of active testosterone 5-alpha-reductase and Ki value is 10 nM.
T0725 Isoliquiritigenin Isoliquiritigenin, an anti-tumor flavonoid from the root of Glycyrrhiza glabra, suppresses aldose reductase (IC50=320 nM).
T1076 Dexamethasone Dexamethasone is a synthetic adrenal corticosteroid with potent anti-inflammatory properties.
T1458 Epalrestat Epalrestat, an aldose reductase inhibitor, is well tolerated in Long-term therapy. It can effectually ameliorate the associated symptoms of diabetic neuropathy and delay the progression of the disease, particularly in patients with limited microangiopathy and good glycemic control.
T1499 Dutasteride Dutasteride is a 5-alpha-reductase inhibitor that inhibits both type-1 and type2 isoforms of the enzyme and is used to treat benign prostatic hyperplasia.
T2013 Ponalrestat Ponalrestat is an aldose reductase inhibitor.
T3665 Tectoridin Tectoridin possesses an estrogenic and thyroid hormone-like agent by activating estrogen and thyroid hormone receptors. Tectoridin has anti-oxidant, anti-inflammatory and hypoglycemic activities; Tectoridin and its five metabolites inhibits the activities of lens aldose reductase in rat (IC₅₀: 1
T3915 GinsenosideRo GinsenosideRo exhibits a Ca2+-antagonistic antiplatelet effect.
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