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T0437 Inosine Inosine is a purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It is an intermediate in the degradation of purines and purine nucleosides to uric acid and in pathways of purine salvage.
T0692 Allopurinol Allopurinol is a Xanthine Oxidase Inhibitor. The mechanism of action of allopurinol is as a Xanthine Oxidase Inhibitor.
T0773 Febuxostat Febuxostat is a xanthine oxidase Inhibitor.
T1363 3-Cyano-4-methoxy-2-pyridinone 1,2-Dihydro-4-methoxy-2-oxo-3-pyridinecarbonitrile was reported as xanthine oxidase inhibitor.
T1694 Oxypurinol Oxipurinol is a xanthine oxidase inhibitor. Oxipurinol is potentially used for the treatment of congestive heart failure.
T2397 Topiroxostat Topiroxostat is a selective xanthine oxidase inhibitor developed for treatment and management of hyperuricemia and gout.
T2841 Plumbagin Plumbagin is a yellow dye, formally derived from naphthoquinone. It is named after the plant genus Plumbago, from which it was originally isolated. It is also commonly found in the carnivorous plant genera Drosera and Nepenthes. It is also a component of the black walnut drupe.
T2858 Baicalein Baicalein is a xanthine oxidase inhibitor.
T2864 Lycopene Lycopene is a linear, unsaturated hydrocarbon carotenoid, the major red pigment in fruits such as tomatoes, pink grapefruit, apricots, red oranges, watermelon, rosehips, and guava. As a class, carotenoids are pigment compounds found in photosynthetic organisms (plants, algae, and some types of fungu
T3061 PF-06463922 PF-06463922 is an orally available, ATP-competitive inhibitor of the receptor tyrosine kinases, anaplastic lymphoma kinase (ALK) and C-ros oncogene 1 (Ros1), with potential antineoplastic activity.
T3374 Dihydrotanshinone I Dihydrotanshinone I is a natural compound extracted from Salvia miltiorrhiza Bunge used for treating of cardiovascular diseases.
T3415 Secoisolariciresinol diglucoside Secoisolariciresinol Diglucoside was cytoprotective in an in vitro model of iron overload-induced redox-inflammatory damage. Secoisolariciresinol Diglucoside (25 mg/kg b.w.) exerts the antihyperglycemic effect by preventing the liver from peroxidation damage through inhibition of ROS level mediated
T3621 Brigatinib Brigatinib is a highly potent and selective ALK inhibitor.
T3678 Entrectinib Entrectinib is an inhibitor of TrkA (IC50: 1.7 nM), TrkB (IC50: 0.1 nM), and TrkC (IC50: 0.1 nM), as well as anaplastic lymphoma kinase (ALK; IC50: 1.6 nM) and C-ros oncogene 1 (ROS1; IC50: 0.2 nM). Entrectinib blocks proliferation of ALK-dependent cell lines, including those with C1156Y or L1196M r
T6376 Allopurinol Sodium Allopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.
T6699 Tempol Tempol is a superoxide scavenger. It has anti-inflammatory, neuroprotective and analgesic effects.
T6917 Oleuropein Oleuropein is an antioxidant polyphenol isolated from olive leaf.
T6947 Piperlongumine Piperlongumine is a natural alkaloid from Piper longum L.. It selectively kills cancer cells and strengthens the level of reactive oxygen species (ROS).
T4309 CIL56 CIL56 is a small molecule that induces cellular ferroptosis through the production of iron-dependent reactive oxygen species (ROS). It also induces accumulation of long-chain saturated, monounsaturated, and polyunsaturated fatty acids in HT-1080 cells in vitro.HT-1080 cells lacking acetyl-CoA carbox
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