NOS

Nitric oxide synthases(NOSs) are a family of enzymes catalyzing the production of nitric oxide (NO) from L-arginine. NO is an important cellular signaling molecule. It helps modulate vascular tone, insulin secretion, airway tone, and peristalsis, and is involved in angiogenesis and neural development. It may function as a retrograde neurotransmitter. Nitric oxide is mediated in mammals by the calcium-calmodulin controlled isoenzymes eNOS (endothelial NOS) and nNOS (neuronal NOS).

Cat. No.	Product Name	CAS No.	Purity
TN4383	Kazinol U 化合物 TN4383	1238116-48-7	98%
TN4383	Kazinol U may have therapeutic value in delaying pancreatic β-cell destruction in type 1 diabetes by blocking the NF-ÎºB pathway in pancreatic β-cells reduces ce...
T3P2855	Chamigrenal 恰米醛	19912-84-6
T3P2855	β-Chamigrenal has anti-inflammatory activity, it has inhibitory effects on lipopolysaccharide-induced nitric oxide and prostaglandin E2 production in RAW 264.7 m...
TN1109	3-O-Acetyl-16α-hydroxydehydrotrametenolic acid 3-O-乙酰基-16Α-羟基松苓新酸	168293-14-9
TN1109	3-O-Acetyl-16α-hydroxydehydrotrametenolic acid (3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid) 是三萜类化合物。它能够作用于 LPS 刺激的 Raw264.7 细胞，减少NO 产生和 iNOS 表达，具有消炎作用。
TN1086	Dehydrotrametenolic acid 松苓新酸	6879-05-6
TN1086	Dehydrotrametenolic acid (Dehydroeburicoic acid) 是从茯苓的菌核中分离的一种甾醇，具有抗肿瘤活性、抗炎和抗糖尿病作用。它通过 caspase-3途径诱导细胞凋亡。
TN5192	Tuberosin 化合物 TN5192	41347-45-9	98%
TN5192	Tuberosin shows anti-inflammatory and antioxidant activities.It demonstrated a significantly potent inhibition on yeast α-glucosidase in a dose dependent manner....
TN5248	Voleneol 化合物 TN5248	70389-88-7	98%
TN5248	1β,6α-Dihydroxyeudesm-4(15)-ene (Voleneol,DE) can attenuate the lipopolysaccharide (LPS)-induced inflammation in BV2 microglial cells, it also can dose-dependent...
TN3366	Ailanthoidol 化合物 TN3366	156398-61-7	98%
TN3366	Ailanthoidol has anti-inflammatory activity, it inhibits inflammatory reactions by macrophages and protects mice from endotoxin shock. It also possesses potentia...
TN3635	Chlojaponilactone B 化合物 TN3635	1449382-91-5	98%
TN3635	Chlojaponilactone B has anti-inflammatory activity, it exhibits pronounced inhibition of nitric oxide (NO) production in lipopolysaccharide (LPS)-induced RAW 264...
TN5164	Trans-Hinokiresinol 化合物 TN5164	17676-24-3	98%
TN5164	Hinokiresinol is a novel inhibitor of LTB4 binding to the human neutrophils, it has antiallergic effect, it inhibits IgE-induced mouse passive cutaneous anaphyla...
TN4038	Eupatolide 泽兰内酯	6750-25-0	98%
TN4038	Eupatolide 是从 Inula japonica 的花中分离出来的，具有抗炎活性。 Eupatolide 可用于研究乳腺癌细胞对 TRAIL 的耐药性。
TN3587	Capillarisin 化合物 TN3587	56365-38-9	98%
TN3587	Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cell...
TN2095	Pomiferin 橙桑黄酮	572-03-2	98%
TN2095	Pomiferin is a natural product inhibitor of carbonic anhydrase I and II isoenzymes. It has anticancer, antibacterial and antidiabetic properties. Pomiferin has a...
TN4633	Neocryptotanshinone II 化合物 TN4633	27468-20-8	98%
TN4633	Neocryptotanshinone inhibits lipopolysaccharide-induced inflammation in RAW264.7 macrophages by suppression of NF-ÎºB and iNOS signaling pathways.
T16830	S-MTC 化合物 T16830	156719-41-4	98%
T16830	S-MTC is a selective inhibitor of type I nitric oxide synthase.
TN1890	Lupeol acetate 乙酸羽扇醇酯	1617-68-1	98%
TN1890	Lupeol acetate possesses antinociceptive, antifertility, and anti-inflammatory properties, the effect probably involves the opioid system, as indicated by the co...
TN1171	6-Dehydrogingerdione 1-脱氢-6-姜酮	76060-35-0	98%
TN1171	1-Dehydro-6-gingerdione is a 5-HT1A receptor partial agonist.
TN1623	Escin IIB 七叶皂苷D	158800-83-0	98%
TN1623	Escin IIB has positive effects on acute inflammation in animals, it can inhibit the induced by serotonin in rats, the hind paw edema induced by carrageenin, and ...
TN5186	Triptoquinone A 化合物 TN5186	142950-86-5	98%
TN5186	Triptoquinone A may be a useful candidate for the development of a drug as a potent inhibitor of iNOS gene over-expression. Triptoquinone A has anti-inflammatory...
T13628	Curvularin 化合物 T13628	10140-70-2	98%
T13628	Curvulin, naturally isolated from Campylobacter curvulans, is a fungal metabolite and a potent mycotoxin that inhibits cytokine-induced nitric oxide synthase (iN...
TN5011	Shizukaol B 化合物 TN5011	142279-40-1	98%
TN5011	Shizukaol B exerts anti-inflammatory effects in LPS-activated microglia partly by modulating JNK-AP-1 signaling pathway; it also shows significant anti-neuroinfl...