||CY-09 is an?NLRP3?inhibitor.
||NOD-IN-1 is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors.
||NLRP3 Inflammasome Inhibitor I
||It is a NLRP3 Inflammasome Inhibitor I.
||CP-456773 (MCC950 and CRID3) is an effective and specific cytokine release inhibitor and NLRP3 inflammasome inhibitor. CP-456773 inhibits IL-1β secretion and caspase 1 processing. MCC950 blocked canonical and noncanonical NLRP3 activation at nanomolar concentrations. MCC950 specifically inhibited a
||MCC950 sodium salt (IC50 of 7.5 nM in BMDMs) is an effective, selective NLRP3 inhibitor.
||Molsidomine is an orally active, long-acting vasodilating drug. It metabolizes in the liver to the active metabolite linsidomine, that releases nitric oxide (NO) upon decay as the actual vasodilating compound.
||Bergenin is a polyphenol, which is an effective antinarcotic agent with antioxidant action.
||Imperatorin is a modulator of p38,ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo.
||Nodinitib-1 is a potent and selective NOD1 inhibitor with an IC50 of 0.56 μM.
||INF39 is a noncytotoxic and irreversible NLRP3 inhibitor.