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MLK
T2048 LY-364947 LY364947 is a potent ATP-competitive inhibitor of TGFβR-I.
T2696 PRT062607 hydrochloride PRT062607 (P505-15, BIIB057) hydrochloride is a novel, highly selective Syk inhibitor.
T6057 URMC-099 URMC-099 is an orally bioavailable, brain penetrant MLK inhibitor (IC50: 19/42/14/150 nM, for MLK1/MLK2/MLK3/DLK), and also inhibits LRRK2 activity (IC50: 11 nM).
T6104 Cerdulatinib hydrochloride Cerdulatinib (PRT-062070) is an oral active, multi-targeted tyrosine kinase inhibitor with IC50 of 12 nM/6 nM/8 nM/0.5 nM and 32 nM for JAK1/JAK2/JAK3/TYK2 and Syk, respectively. Also inhibits 19 other tested kinases with IC50 less than 200 nM.
T6904 Necrosulfonamide Necrosulfonamide is a selective and effective necrosis inhibitor and blocks the MLKL.
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