||GSK923295 is a selective allosteric inhibitor of CENP-E kinesin motor ATPase(Ki=3.2 nM).
||ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.
||AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM.
||Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor.
||MPI-0479605 is an ATP competitive and selective inhibitor.
||BAY 1217389 is an effective and selective inhibitor of the monopolar spindle 1 (MPS1) kinase (IC50<10 nM).
||Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.
||K858 is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.
||Dimethylenastron, an Eg5 inhibitor, arrests cells with monopolar spindles to which all chromosomes attach in a syntelic manner.