||Eplerenone is an aldosterone receptor antagonist and potassium-sparing diuretic used in the therapy of hypertension. Eplerenone therapy has been associated with transient elevations in serum aminotransferase levels, but has yet to be linked to cases of clinically apparent drug induced liver disease.
||Fluticasone propionate, derived from fluticasone used to remedy asthma and allergic rhinitis, is a high affinity, selective GR (glucocorticoid receptor) agonist.
||Nimodipine, a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells.
||Canrenone is an aldosterone antagonist with potassium-sparing diuretic activity.
||Drospirenone is a synthetic spironolactone analogue and progestin with progestational and anti-mineralocorticoid activity.
||Potassium canrenoate is a synthetic pregnadiene derivative with anti-aldosterone activity.
||TPI-1 is a SHP-1 inhibitor.
||LY404039 is an effective agonist of recombinant human mGlu2(Ki =149 nM)/mGlu3(Ki =92 nM).