Cat. No. | Product Name | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
T4009 | NS 1209
化合物NS 1209
|
205645-02-9 |
|
|
NS 1209 (SPD 502) 是一种 AMPA 受体拮抗剂。 | ||||
T15369 | Gamma-DGG
化合物 T15369
|
6729-55-1 | 98% |
|
gamma-DGG is a competitive blocker of AMPA receptor. | ||||
T11906 | LY 541850
化合物 T11906
|
852679-76-6 | 98% |
|
LY541850 is a selective orthosteric mGlu2 agonist and mGlu3 antagonist with IC50 values of 0.161 μM and 0.038 μM, respectively.LY 541850 is claimed from human io... | ||||
T15692 | L-AP4
化合物 T15692
|
23052-81-5 | 98% |
|
L-APB is an effective and specific agonist for the group III mGluRs (EC50s: 0.13, 0.29, 1.0, 249 μM for mGlu4, mGlu8, mGlu6, and mGlu7 receptors, respectively). | ||||
T11907 | Pomaglumetad methionil anhydrous
化合物 T11907
|
635318-55-7 | 98% |
|
LY2140023 has the potential for schizophrenia.LY2140023 is an orally active prodrug of LY404039. LY404039 is a selective metabotropic glutamate 2/3 receptor agon... | ||||
T12520 | Pomaglumetad methionil
化合物 T12520
|
956385-05-0 | 98% |
|
Pomaglumetad methionil is an oral methionine prodrug of the potent specific agonist of mGlu2/3 receptor LY404039. | ||||
T12025 | MFZ 10-7 hydrochloride
化合物 T12025
|
1779796-36-9 | 98% |
|
MFZ 10-7 hydrochloride is a highly potent and selective negative allosteric modulator of mGluR5 NAM | ||||
T11911 | LY3020371 hydrochloride
化合物 T11911
|
1377615-44-5 | 98% |
|
LY3020371 hydrochloride exerts an antidepressant-like signature in vivo. LY3020371 hydrochloride is a potent, selective metabotropic glutamate 2/3 receptor (mGlu... | ||||
T21935 | AMN082
化合物AMN 082 dihydrochloride
|
97075-46-2 | 98% |
|
AMN082 (AMN 082 dihydrochloride) 是可口服,可透过血脑屏障的选择性mGluR7激动剂,通过跨膜区的变构位点直接激活受体信号,具有抗抑郁作用。 | ||||
T13319 | VU0652835
化合物 T13319
|
1848252-81-2 | 98% |
|
VU0652835 is a negative allosteric modulator of metabotropic glutamate receptor subtype 5 (mGlu5) (IC50: 81 nM). | ||||
T15618 | JNJ-46281222
化合物 T15618
|
1254980-38-5 | 98% |
|
JNJ-46281222 is an metabotropic glutamate (mGlu) 2-selective, highly potent PAM (positive allosteric modulator). It has nanomolar affinity (Kd = 1.7 nM) and a hi... | ||||
T11311L | Foliglurax
化合物 T11311L
|
1883329-51-8 | 98% |
|
Foliglurax is a highly selective brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) (EC50: 79 nM). | ||||
T15823 | LYPLAL1-IN-1
化合物 T15823
|
1966129-74-7 | 98% |
|
LYPLAL1-IN-1 is a selective covalent small-molecule inhibitor of Lysophospholipase-like 1 (IC50: 0.006 μM). LYPLAL1-IN-1 also enhances glucose production. | ||||
T12118 | MSOP
化合物 T12118
|
66515-29-5 | 98% |
|
MSOP is a selective antagonist of group III metabotropic glutamate receptor (KD of 51 μM for the L-AP4-sensitive presynaptic mGluR). | ||||
T17248 | VU6001376
化合物 T17248
|
1968546-34-0 | 98% |
|
VU6001376 is an effective and selective positive allosteric modulator of the metabotropic glutamate receptor 4 (EC50: 50.1 nM). | ||||
TQ0114 | CMPDA
化合物CMPDA
|
380607-77-2 | 98% |
|
CMPDA is a positive allosteric modulator of AMPA receptors (EC50s: 45.4 nM/63.4 nM for GluA2i/GluA2o receptor). | ||||
T14615 | Biphenylindanone A
化合物 T14615
|
866823-73-6 | 98% |
|
Biphenylindanone A is a selective potentiator of human mGluR2 (hmGluR2),and for the treatment of neurological disorders. | ||||
T23288 | (S)-3,4-DCPG
化合物(S)-3,4-DCPG
|
201730-11-2 | 98% |
|
(S)-3,4-DCPG ((S)-3,4-Dicarboxyphenylglycine) 是人代谢型谷氨酸受体 8a (mGluR8a) 的选择性激动剂。 | ||||
T6725 | VU 0357121
化合物VU 0357121
|
433967-28-3 | 99.99% |
|
VU 0357121 是一种高选择性的mGlu5R 正变构调节剂 ,EC50为 33 nM。 | ||||
T3477 | E4CPG
化合物E4CPG
|
170846-89-6 | 99.96% |
|
E4CPG 是一种 I/II 组代谢型谷氨酸受体的拮抗剂,可抑制单突触后机制中突触后电流 (IPSC) 增强的成对脉冲比。 |