||Leupeptin hemisulfate is a reversible, competitive serine/cysteine protease inhibitor. It is an orally active, antioxidant and anti-inflammatory agent.
||Calpeptin is a potent, cell-permeable calpain inhibitor.
||N-ethylmaleimide is a sulfhydryl reagent that is widely used in experimental biochemical studies.
||CA-074 methyl ester
||CA-074 methyl ester is a specific inhibitor of Cathepsin B with neuroprotective, anti-cancer, and anti-inflammatory effects.
||AX-024 hydrochloride is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interferon-γ (IFN-γ), IL-10 and IL-17A.
||PD 151746 is a selective, cell-permeable calpain inhibitor (Ki: 0.26/5.33 μM, μ-Calpain/m-calpain).
||Z-FA-FMK can irreversibly inhibit cysteine protease and also inhibit effector caspases.
||Cathepsin Inhibitor 1
||Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively.
||Phenylmethanesulfonyl fluoride (PMSF) is an enzyme inhibitor that inactivates IRC-50 arvin, subtilisin, and the fatty acid synthetase complex.
||Balicatib is a potent and selective inhibitor of cathepsin K, used in trials studying the treatment of osteoporosis.
||Dexibuprofen, S(+)-ibuprofen, is a non-steroidal anti-inflammatory drug (NSAID), inhibiting cyclooxygenase (COX).
||Cysteamine is a Cystine Depleting Agent. The mechanism of action of cysteamine is as a Cystine Disulfide Reduction.
||Odanacatib is an inhibitor of cathepsin K with potential anti-osteoporotic activity.
||E-64 is an irreversible and specific cysteine protease inhibitor. The IC50 of E-64 for papain is 9 nM.
||Loxistatin Acid (E-64C)
||Loxistatin Acid (E-64C), a derivative of E-64, is an irreversible and membrane-permeant cysteine protease inhibitor.
||P005091 is a selective and potent inhibitor of ubiquitin-specific protease 7 (USP7) with EC50 of 4.2 μM.
||Aloxistatin is an inhibitor of cysteine protease with blood platelet aggregation inhibiting activity. Aloxistatin is an irreversible, membrane-permeable inhibitor of lysosomal and cytosolic cysteine proteases with the ability to inhibit calpain activity in intact platelets.