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Cysteine Protease
T6564 Leupeptin Hemisulfate Leupeptin hemisulfate is a reversible, competitive serine/cysteine protease inhibitor. It is an orally active, antioxidant and anti-inflammatory agent.
T6432 Calpeptin Calpeptin is a potent, cell-permeable calpain inhibitor.
T3088 N-Ethylmaleimide N-ethylmaleimide is a sulfhydryl reagent that is widely used in experimental biochemical studies.
T3420 CA-074 methyl ester CA-074 methyl ester is a specific inhibitor of Cathepsin B with neuroprotective, anti-cancer, and anti-inflammatory effects.
T4403 AX-024 HCl AX-024 hydrochloride is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interferon-γ (IFN-γ), IL-10 and IL-17A.
T2493 PD 151746 PD 151746 is a selective, cell-permeable calpain inhibitor (Ki: 0.26/5.33 μM, μ-Calpain/m-calpain).
T6738 Z-FA-FMK Z-FA-FMK can irreversibly inhibit cysteine protease and also inhibit effector caspases.
T6015 Cathepsin Inhibitor 1 Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively.
T0789 PMSF Phenylmethanesulfonyl fluoride (PMSF) is an enzyme inhibitor that inactivates IRC-50 arvin, subtilisin, and the fatty acid synthetase complex.
T1850 Balicatib Balicatib is a potent and selective inhibitor of cathepsin K, used in trials studying the treatment of osteoporosis.
T0448 (S)-(+)-Ibuprofen Dexibuprofen, S(+)-ibuprofen, is a non-steroidal anti-inflammatory drug (NSAID), inhibiting cyclooxygenase (COX).
T1080 Cysteamine Cysteamine is a Cystine Depleting Agent. The mechanism of action of cysteamine is as a Cystine Disulfide Reduction.
T6035 Odanacatib (MK-0822) Odanacatib is an inhibitor of cathepsin K with potential anti-osteoporotic activity.
T6037 E-64 E-64 is an irreversible and specific cysteine protease inhibitor. The IC50 of E-64 for papain is 9 nM.
T6573 Loxistatin Acid (E-64C) Loxistatin Acid (E-64C), a derivative of E-64, is an irreversible and membrane-permeant cysteine protease inhibitor.
T6925 P005091 P005091 is a selective and potent inhibitor of ubiquitin-specific protease 7 (USP7) with EC50 of 4.2 μM.
T6040 Aloxistatin Aloxistatin is an inhibitor of cysteine protease with blood platelet aggregation inhibiting activity. Aloxistatin is an irreversible, membrane-permeable inhibitor of lysosomal and cytosolic cysteine proteases with the ability to inhibit calpain activity in intact platelets.
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