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CRM1
T1844 KPT-330 KPT-330 is a CRM1-selective inhibitor of nuclear export. It inhibits protein trafficking from the nucleus and induces cell cycle arrest and apoptosis in mesothelioma cells.
T2425 KPT-185 KPT-185 is a selective CRM1 inhibitor, inducing apoptosis,cell-cycle arrest.
T6074 KPT-276 KPT-276 is an orally bioavailable selective inhibitor of nuclear export (SINE) that irreversibly bind to CRM1 and block the function of CRM1.
T6123 Verdinexor (KPT-335) Verdinexor (KPT-335), a specific XPO1/CRM1 inhibitor, are orally bioavailable.
T6106 Selinexor (KPT-330) Selinexor is an orally available, small molecule inhibitor of CRM1 (chromosome region maintenance 1 protein, exportin 1 or XPO1), with potential antineoplastic activity.
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